VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 249 prodotti di "VEGFR"
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SKLB1002
CAS:<p>SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.</p>Formula:C13H12N4O2S2Purezza:98.51% - >99.99%Colore e forma:SolidPeso molecolare:320.39Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurezza:99.03% - 99.79%Colore e forma:SolidPeso molecolare:522.96PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:443.44Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formula:C21H17ClF4N4O4Purezza:99.69%Colore e forma:SolidPeso molecolare:500.83VEGFR2-IN-2
CAS:VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formula:C15H11BrN2OPurezza:99.504%Colore e forma:SolidPeso molecolare:315.16Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36XL092
CAS:<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Formula:C29H25FN4O5Purezza:98.60%Colore e forma:SolidPeso molecolare:528.53(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purezza:98.93% - 99.72%Colore e forma:SolidPeso molecolare:312.45Tanshinone IIA
CAS:<p>Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.</p>Formula:C19H18O3Purezza:99.04% - >99.99%Colore e forma:Cherry CrystalPeso molecolare:294.34Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purezza:99.82%Colore e forma:SolidPeso molecolare:482.51Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurezza:98.27%Colore e forma:SolidPeso molecolare:547.99Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purezza:99.7% - >99.99%Colore e forma:White SolidPeso molecolare:475.35PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purezza:98.15% - 98.21%Colore e forma:Yellow SolidPeso molecolare:523.67TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purezza:99.37%Colore e forma:SolidPeso molecolare:445.47Bevacizumab
CAS:<p>Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.</p>Purezza:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Colore e forma:LiquidPeso molecolare:146.53 kDaIsolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.29PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purezza:98.45% - 99.93%Colore e forma:SolidPeso molecolare:319.36SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Formula:C17H16N2OPurezza:>99.99%Colore e forma:SolidPeso molecolare:264.32Semaxinib
CAS:<p>Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.</p>Formula:C15H14N2OPurezza:99.84%Colore e forma:Yellow To Yellow OrangePeso molecolare:238.28
