c-Met/HGFR
Gli inibitori di c-Met/HGFR mirano al Recettore del Fattore di Crescita degli Epatociti (c-Met), una tirosina chinasi coinvolta in processi cellulari come crescita, motilità e morfogenesi. La segnalazione di c-Met è implicata nella progressione del cancro, nella metastasi e nella resistenza alle terapie. L'inibizione di c-Met può interrompere la crescita e la diffusione del tumore, rendendo questi inibitori preziosi nella ricerca sul cancro. Presso CymitQuimica, offriamo inibitori di c-Met/HGFR per supportare la tua ricerca in oncologia, metastasi e terapie oncologiche mirate.
Trovati 148 prodotti per "c-Met/HGFR".
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Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purezza:98.11% - 99.87%Colore e forma:White SolidPeso molecolare:718.08X-376
CAS:X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase ALK with potential antineoplastic activity.Formula:C25H25Cl2FN6O3Purezza:97.87%Colore e forma:SolidPeso molecolare:547.41Ref: TM-T3550
1mg34,00€2mg48,00€5mg93,00€1mL*10mM (DMSO)100,00€10mg113,00€25mg244,00€50mg405,00€100mg550,00€Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurezza:99% - 99.87%Colore e forma:White SolidPeso molecolare:450.337Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:447.51BMS-2
CAS:BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formula:C25H16F2N4O3Purezza:98.33%Colore e forma:SolidPeso molecolare:458.42Ref: TM-T8326
1mg67,00€2mg88,00€5mg148,00€1mL*10mM (DMSO)150,00€10mg230,00€25mg430,00€50mg622,00€100mg898,00€Golvatinib
CAS:Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factorFormula:C33H37F2N7O4Purezza:98.24% - 99.93%Colore e forma:SolidPeso molecolare:633.69Ref: TM-T6517
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)92,00€10mg96,00€25mg141,00€50mg187,00€100mg333,00€Foretinib phosphate
CAS:Foretinib phosphate, an oral MET/VEGFR2 inhibitor GSK1363089, may curb tumor growth and spread.Formula:C34H40F2N4O14P2Colore e forma:SolidPeso molecolare:828.65Hepln-13
CAS:Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.Formula:C17H13BrN2Purezza:97.67%Colore e forma:SolidPeso molecolare:325.203Ref: TM-T25492
1mg35,00€2mg52,00€5mg80,00€1mL*10mM (DMSO)92,00€10mg119,00€25mg231,00€50mg344,00€100mg480,00€200mg663,00€Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurezza:99.93%Colore e forma:SolidPeso molecolare:728.79MK-8033
CAS:MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).Formula:C25H21N5O3SPurezza:97.16% - 99.93%Colore e forma:SolidPeso molecolare:471.53c-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formula:C26H21F2N5O3Purezza:98.72% - 98.73%Colore e forma:White SolidPeso molecolare:489.47Ref: TM-T4332
1mg37,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg224,00€50mg353,00€100mg578,00€200mg797,00€AMG-208
CAS:AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.Formula:C22H17N5O2Purezza:98.56%Colore e forma:SolidPeso molecolare:383.4AMG-337
CAS:AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).Formula:C23H22FN7O3Purezza:99.26% - 99.9%Colore e forma:White SolidPeso molecolare:463.46Ref: TM-T3209
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)81,00€10mg117,00€25mg187,00€50mg333,00€100mg495,00€200mg710,00€SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurezza:98.07%Colore e forma:SolidPeso molecolare:821.12Ref: TM-T5349
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)102,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€PHA-665752
CAS:PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Formula:C32H34Cl2N4O4SPurezza:97.05% - 98.82%Colore e forma:SolidPeso molecolare:641.61BMS 777607
CAS:BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.Formula:C25H19ClF2N4O4Purezza:98.89% - >99.99%Colore e forma:SolidPeso molecolare:512.89Ref: TM-T2699
1mg34,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg340,00€100mg505,00€500mg1.108,00€Glumetinib
CAS:Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).Formula:C21H17N9O2SPurezza:99.79%Colore e forma:White SolidPeso molecolare:459.48Tivantinib
CAS:Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.Formula:C23H19N3O2Purezza:98% - 99.41%Colore e forma:Yellow SolidPeso molecolare:369.42Pamufetinib mesylate
CAS:Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formula:C28H27FN4O7S2Purezza:98.91%Colore e forma:White SolidPeso molecolare:614.67Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurezza:98.73% - 98.87%Colore e forma:SolidPeso molecolare:486.8Ref: TM-T8399
5mg34,00€1mL*10mM (DMSO)35,00€10mg50,00€25mg78,00€50mg94,00€100mg131,00€200mg162,00€500mg215,00€
