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PYK2

PYK2

Gli inibitori di PYK2 sono composti che inibiscono la chinasi tirosina ricca di prolina 2 (PYK2), una tirosina chinasi non recettoriale coinvolta in processi cellulari come adesione, migrazione e sopravvivenza. PYK2 è implicata nella metastasi del cancro e nei disturbi neurologici. Presso CymitQuimica, offriamo inibitori di PYK2 per supportare la tua ricerca sulla metastasi del cancro, neurobiologia e segnalazione cellulare.

Trovati 7 prodotti di "PYK2"

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  • BT-Amide
    Targetmol
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    BT-Amide

    <p>BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.</p>
    Formula:C29H38ClN7O11P2
    Colore e forma:Solid
    Peso molecolare:758.053

    Ref: TM-T204768

  • PF-562271 besylate
    Targetmol
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    PF-562271 besylate

    CAS:
    <p>PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.</p>
    Formula:C21H20F3N7O3S·C6H6O3S
    Purezza:97.65% - 99.01%
    Colore e forma:Solid
    Peso molecolare:665.66

    Ref: TM-T6177

  • PF-431396
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    PF-431396

    CAS:
    <p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>
    Formula:C22H21F3N6O3S
    Purezza:98.83% - 99.82%
    Colore e forma:Solid
    Peso molecolare:506.5

    Ref: TM-T2314

  • PF-562271 hydrochloride
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    PF-562271 hydrochloride

    CAS:
    <p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>
    Formula:C21H20F3N7O3SHCl
    Purezza:97.08%
    Colore e forma:Solid
    Peso molecolare:543.95

    Ref: TM-T21768

  • PF-562271
    Targetmol
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    PF-562271

    CAS:
    <p>PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).</p>
    Formula:C21H20F3N7O3S
    Purezza:97.17% - >99.99%
    Colore e forma:Solid
    Peso molecolare:507.49

    Ref: TM-T2465

  • NVP-TAE 226
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    NVP-TAE 226

    CAS:
    <p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>
    Formula:C23H25ClN6O3
    Purezza:98.07% - 98.78%
    Colore e forma:Solid
    Peso molecolare:468.94

    Ref: TM-T1918

  • PF-4618433
    Targetmol
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    PF-4618433

    CAS:
    <p>PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.</p>
    Formula:C24H27N7O2
    Purezza:99.95%
    Colore e forma:Solid
    Peso molecolare:445.52

    Ref: TM-T22397