Src
Gli inibitori di Src sono composti che prendono di mira le chinasi della famiglia Src, coinvolte in vari processi cellulari, tra cui crescita, differenziazione e angiogenesi. Le chinasi Src svolgono un ruolo critico nelle vie di segnalazione che promuovono la formazione di nuovi vasi sanguigni nei tumori. Inibendo Src, è possibile interrompere queste vie, riducendo così l'angiogenesi e la crescita tumorale. Gli inibitori di Src sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo terapeutico. Presso CymitQuimica, offriamo una selezione completa di inibitori di Src di alta qualità per supportare la tua ricerca in oncologia, segnalazione cellulare e angiogenesi.
Trovati 79 prodotti di "Src"
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Dasatinib
CAS:Formula:C22H26ClN7O2SPurezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:488.01NVP-BHG 712
CAS:Formula:C26H20F3N7OPurezza:>95.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:503.49Tirbanibulin Mesylate
CAS:<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formula:C27H33N3O6SPurezza:99%Colore e forma:SolidPeso molecolare:527.63Dasatinib monohydrate
CAS:<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Formula:C22H28ClN7O3SPurezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:506.03Bosutinib
CAS:<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formula:C26H29Cl2N5O3Purezza:98.98% - 99.9%Colore e forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecolare:530.45CSF1R-IN-2
CAS:<p>CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).</p>Formula:C20H20FN7O2Purezza:99.29%Colore e forma:SolidPeso molecolare:409.42Hck-IN-1
CAS:<p>Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.</p>Formula:C16H11ClN6O3SPurezza:99.07%Colore e forma:SolidPeso molecolare:402.81Ref: IN-DA00AP0L
1gPrezzo su richiesta1mg51,00€5mg68,00€10mg80,00€25mg102,00€50mg126,00€100mg193,00€250mg273,00€Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formula:C22H26ClN7O2SPurezza:99.59% - 99.86%Colore e forma:Pale-Yellow SolidPeso molecolare:488.01Adrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65Caffeic acid-pYEEIE
CAS:<p>Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,).</p>Formula:C39H50N5O19PPurezza:98%Colore e forma:SolidPeso molecolare:923.82Hck-IN-2
<p>Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.</p>Formula:C36H35FN6O10Colore e forma:SolidPeso molecolare:730.696Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Colore e forma:Odour SolidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Colore e forma:Odour SolidSecretin, canine
CAS:<p>Secretin: endocrine hormone, increases bicarbonate-rich pancreatic fluid, regulates canine gastric functions via Src kinase pathway.</p>Formula:C131H222N44O41Purezza:98%Colore e forma:SolidPeso molecolare:3069.43Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
CAS:<p>Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.</p>Formula:C32H46N5O17PPurezza:98%Colore e forma:SolidPeso molecolare:803.71LCB 03-0110 dihydrochloride
CAS:<p>LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2</p>Formula:C24H25Cl2N3O2SPurezza:99.9%Colore e forma:SoildPeso molecolare:490.45Anti-Src Antibody (1E789)
<p>Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.</p>Colore e forma:Odour LiquidPP 2
CAS:Formula:C15H16ClN5Purezza:>97.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:301.781-Naphthyl PP1
CAS:Formula:C19H19N5Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:317.40Saracatinib
CAS:Formula:C27H32ClN5O5Purezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:542.03WHI-P154
CAS:Formula:C16H14BrN3O3Purezza:>98.0%(HPLC)Colore e forma:White to Yellow to Orange powder to crystalPeso molecolare:376.21Bosutinib
CAS:Formula:C26H29Cl2N5O3Purezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:530.45PP 1
CAS:Formula:C16H19N5Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:281.36A-770041
CAS:<p>A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.</p>Formula:C34H39N9O3Purezza:99.23% - 99.86%Colore e forma:SolidPeso molecolare:621.73AP23846
CAS:<p>AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.</p>Formula:C24H34N5OPPurezza:97.83%Colore e forma:SolidPeso molecolare:439.53squarunkinA
CAS:<p>squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-</p>Formula:C25H32F3N5O4Purezza:99.29%Colore e forma:SolidPeso molecolare:523.55PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formula:C17H17N7Purezza:98.45% - 99.67%Colore e forma:SolidPeso molecolare:319.36AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formula:C29H28F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:535.56Scutellarein
CAS:<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Formula:C15H10O6Purezza:98.02% - 99.63%Colore e forma:SolidPeso molecolare:286.24ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formula:C21H25N7Purezza:97.63% - ≥95%Colore e forma:SolidPeso molecolare:375.47RK-24466
CAS:<p>RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.</p>Formula:C23H22N4OPurezza:98.07%Colore e forma:SolidPeso molecolare:370.45PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Formula:C28H30N6OSPurezza:97.56% - >99.99%Colore e forma:SolidPeso molecolare:498.64SU6656
CAS:<p>SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.</p>Formula:C19H21N3O3SPurezza:98.21% - 98.73%Colore e forma:SolidPeso molecolare:371.45PP2
CAS:<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Formula:C15H16ClN5Purezza:98% - 98.21%Colore e forma:White SolidPeso molecolare:301.77PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Formula:C26H35Cl2N7OPurezza:99.92%Colore e forma:SolidPeso molecolare:532.51β-Hydroxyisovalerylshikonin
CAS:<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Formula:C21H24O7Purezza:98.16%Colore e forma:SolidPeso molecolare:388.41Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formula:C37H35F9N8O11Purezza:97.09% - 99.84%Colore e forma:SolidPeso molecolare:938.71Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formula:C31H32N8O5Purezza:98%Colore e forma:SolidPeso molecolare:596.64AD80
CAS:<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Formula:C22H19F4N7OPurezza:99.49% - 99.75%Colore e forma:SolidPeso molecolare:473.43Tolimidone
CAS:<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Formula:C11H10N2O2Purezza:99.85% - 99.85%Colore e forma:SolidPeso molecolare:202.21eCF506
CAS:<p>eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)</p>Formula:C26H38N8O3Purezza:97.85% - 98.16%Colore e forma:SolidPeso molecolare:510.63Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purezza:99.53% - 99.79%Colore e forma:SolidPeso molecolare:553.59UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formula:C30H31F3N8O3SPurezza:98.72% - 99.52%Colore e forma:SolidPeso molecolare:640.68Saracatinib
CAS:<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Formula:C27H32ClN5O5Purezza:98% - 99.63%Colore e forma:SolidPeso molecolare:542.031-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Formula:C19H19N5Purezza:99.85%Colore e forma:White Cyrstalline SolidPeso molecolare:317.39Src Inhibitor 1
CAS:<p>Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.</p>Formula:C22H19N3O3Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:373.4Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formula:C29H27F3N6OPurezza:98% - 99.60%Colore e forma:SolidPeso molecolare:532.56
