IGF-1R
Gli inibitori di IGF-1R sono composti che prendono di mira specificamente il recettore del fattore di crescita insulino-simile 1 (IGF-1R), una tirosina chinasi recettore coinvolta nella crescita, sviluppo e sopravvivenza cellulare. La segnalazione dell'IGF-1R svolge un ruolo significativo nella progressione del cancro, rendendo questi inibitori preziosi nella ricerca oncologica. Presso CymitQuimica, offriamo inibitori di IGF-1R per supportare la tua ricerca in biologia del cancro, endocrinologia e sviluppo di terapie mirate.
Trovati 99 prodotti di "IGF-1R"
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Indirubin Derivative E804
CAS:Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with potential antitumor activity.Formula:C20H19N3O4Purezza:98.54%Colore e forma:SolidPeso molecolare:365.38Ref: TM-T11654
1mg42,00€5mg88,00€10mg124,00€25mg197,00€50mg293,00€100mg434,00€200mg622,00€1mL*10mM (DMSO)93,00€Dusigitumab
CAS:Dusigitumab (MEDI573) is a fully humanised monoclonal antibody targeting IGF1/IGF2, inhibiting IGF1/IGF2-induced IGF-1R phosphorylation.
Purezza:95% - 95%Colore e forma:LiquidVeligrotug
CAS:Veligrotug is an IV anti-IGF-1R antibody for thyroid eye disease, reducing diplopia and orbital inflammation, supporting autoimmune ophthalmopathy research.Purezza:95% - 96.7% (SDS-PAGE); 99.8% (SEC-HPLC)Colore e forma:LiquidS961
CAS:S961: High-affinity IR antagonist; IC50: HIR-A 0.048 nM, HIR-B 0.027 nM, HIGF-IR 630 nM.Formula:C211H297N55O71S2Purezza:98%Colore e forma:SolidPeso molecolare:4804.13BMS-754807
CAS:BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.Formula:C23H24FN9OPurezza:99.69% - 99.94%Colore e forma:SolidPeso molecolare:461.49Ref: TM-T2349
1mg49,00€2mg70,00€5mg96,00€10mg166,00€25mg328,00€50mg537,00€100mg772,00€1mL*10mM (DMSO)116,00€D-(+)-Sorbose
CAS:D-(+)-Sorbose, an enantiomer inhibiting disaccharidase, lowers glucose and insulin post-meal in rats, possibly preventing diabetes.Formula:C6H12O6Colore e forma:SolidPeso molecolare:180.16KU14R
CAS:KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.Formula:C13H14N2OPurezza:98%Colore e forma:White SolidPeso molecolare:214.26AZ12253801
CAS:AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.Formula:C21H22N8OPurezza:98%Colore e forma:SolidPeso molecolare:402.45BM-131246
CAS:BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.Formula:C22H20N2O4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:408.47IMP2-IN-2
CAS:IMP2-IN-2: potent, selective IMP2 inhibitor; IC50s: 120.9 μM (RNA_A), 236.7 μM (RNA_B); used in cancer research.Formula:C22H19F3N2O3SColore e forma:SolidPeso molecolare:448.46H-1356
CAS:H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.Formula:C55H88N14O15S2Colore e forma:SolidPeso molecolare:1249.5I-OMe-Tyrphostin AG 538
CAS:I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.Formula:C17H12INO5Purezza:98.8%Colore e forma:SolidPeso molecolare:437.19Ref: TM-T11593
1mg56,00€5mg119,00€10mg187,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)131,00€NT219
CAS:NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.Formula:C16H14BrNO5SPurezza:98.06% - 99.72%Colore e forma:SolidPeso molecolare:412.26Protonstatin-1
CAS:Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.Formula:C8H5NO2S2Purezza:99.77%Colore e forma:SolidPeso molecolare:211.26Ref: TM-T71812
1mg90,00€5mg215,00€10mg313,00€25mg537,00€50mg713,00€100mg982,00€200mg1.333,00€1mL*10mM (DMSO)236,00€NBI-6024
CAS:NBI-6024, an altered peptide ligand (APL), serves as an epitope for interferon-gamma-producing T helper lymphocytes associated with inflammation in patientsFormula:C66H112N20O21Colore e forma:SolidPeso molecolare:1521.72BMS-695735
CAS:BMS-695735: benzimidazole, inhibits IGF-1 receptor, broad antitumor effects, affects CYP3A4, low solubility, binds plasma proteins.Formula:C26H31ClFN7OColore e forma:SolidPeso molecolare:512.02Tyrphostin AG 538
CAS:Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.Formula:C16H11NO5Purezza:98.75%Colore e forma:SoildPeso molecolare:297.26IGF-1R inhibitor-4
CAS:IGF-1Rinhibitor-4 (compound 22) is a potent inhibitor of IGF-1R, demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound plays a significant role in cancer research.Formula:C13H15ClN4OColore e forma:SolidPeso molecolare:278.737AGL-2263
CAS:AGL-2263 is a blocker of insulin receptor (IR)Formula:C17H10N2O5Colore e forma:SolidPeso molecolare:322.27
