Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Chloroquine dihydrochloride
CAS:Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.Formula:C18H27Cl2N3Colore e forma:SolidPeso molecolare:356.33Lamotrigine-d3
CAS:Lamotrigine-d3 is a deuterated compound of Lamotrigine. Lamotrigine has a CAS number of 84057-84-1. Lamotrigine is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity.Formula:C9D3H4Cl2N5Peso molecolare:259.11Apatinib-d8
CAS:Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM). In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.Formula:C24H15D8N5OPeso molecolare:405.52Gavilimomab
CAS:Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).Purezza:95%Colore e forma:LiquidPeso molecolare:0PBA-1105
CAS:PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.Formula:C39H48N2O6Colore e forma:SolidPeso molecolare:640.81Erlotinib mesylate
CAS:Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.Formula:C23H27N3O7SPurezza:98%Colore e forma:SolidPeso molecolare:489.54Seriniquinone
CAS:Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.Formula:C20H8O4SPurezza:98%Colore e forma:SolidPeso molecolare:344.34TAMRA alkyne, 6-isomer
CAS:<p>TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.</p>Formula:C28H25N3O4Colore e forma:SolidPeso molecolare:467.52Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Formula:C16H25NO4·HClPurezza:98.72% - 99.48%Colore e forma:White SolidPeso molecolare:331.15Resveratrol analog 2
CAS:Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.Formula:C16H13FO3Purezza:98%Colore e forma:SolidPeso molecolare:272.27YT-8-8
CAS:<p>YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.</p>Formula:C18H23FN2O2Colore e forma:SolidPeso molecolare:318.39SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurezza:98.62% - 99.53%Colore e forma:Orange PowderPeso molecolare:568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formula:C38H44Cl2F2N2O7Purezza:99.949%Colore e forma:SolidPeso molecolare:749.67SR12418
CAS:SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.Formula:C31H30FNO3Purezza:99.96%Colore e forma:SolidPeso molecolare:483.57VUF10132
CAS:<p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>Formula:C19H13BrCl4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:523.03IZCZ-3
CAS:IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.Formula:C46H49N7OPurezza:98%Colore e forma:SolidPeso molecolare:715.93(R)-Hydroxychloroquine
CAS:(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.Formula:C18H26ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:335.87AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurezza:99.55% - 99.89%Colore e forma:SolidPeso molecolare:402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgPrezzo su richiestaLS2265
CAS:LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.Formula:C19H20ClNO6SPurezza:98%Colore e forma:SolidPeso molecolare:425.88AGN 205327
CAS:AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.Formula:C24H26N2O3Purezza:99.45% - 99.71%Colore e forma:SolidPeso molecolare:390.47YOK-2204
CAS:YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.Formula:C28H35NO4Colore e forma:SolidPeso molecolare:449.58OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Formula:C25H24F3N3O6S2Colore e forma:SolidPeso molecolare:583.6YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formula:C20H19ClN4O3Colore e forma:SolidPeso molecolare:398.85ATG7-IN-3
CAS:ATG7-IN-3 (Compound 18) is an effective ATG7 inhibitor (IC₅₀ = 48 nM), suppressing autophagy, suitable for research into gliomas and colorectal cancers.Formula:C11H16N6O5S2Purezza:99.74% - 99.88%Colore e forma:SolidPeso molecolare:376.41Ref: TM-T61552
1mg279,00€5mgPrezzo su richiesta10mgPrezzo su richiesta25mg1.388,00€50mg1.872,00€100mg2.527,00€Evogliptin
CAS:Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.Formula:C19H26F3N3O3Colore e forma:SolidPeso molecolare:401.42IT1t
CAS:IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.Formula:C21H34N4S2Purezza:98%Colore e forma:SolidPeso molecolare:406.65(Rac)-BL-918
CAS:(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.Formula:C23H15F8N3OSPurezza:97.03%Colore e forma:SolidPeso molecolare:533.44Ref: TM-T12662
1mg47,00€5mg87,00€10mg133,00€25mg263,00€50mg455,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€MPM-1
MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.Formula:C34H44F6N4O7Colore e forma:SolidPeso molecolare:734.73PX20606 trans racemate
CAS:PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).Formula:C29H22Cl3NO4Purezza:98%Colore e forma:SolidPeso molecolare:554.85MRT-68601 HCl
CAS:MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.Formula:C25H34N6O2Purezza:98%Colore e forma:SolidPeso molecolare:450.58Autophagy inducer 4
CAS:Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.Formula:C32H37NO6Colore e forma:SolidPeso molecolare:531.64eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formula:C25H19Br2ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:602.71KRH-1636
CAS:KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.Formula:C32H37N7O2Colore e forma:SolidPeso molecolare:551.68(S)-Hydroxychloroquine
CAS:(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.Formula:C18H26ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:335.87TUN-92046
CAS:TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.Formula:C7H10O5Purezza:95.48% - 98.58%Colore e forma:SolidPeso molecolare:174.15TN-14003
CAS:TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.Formula:C90H141N33O18S2Colore e forma:SolidPeso molecolare:2037.42VUF5834
CAS:VUF5834 is a full inverse agonist of CXCR3 N3.35A.Formula:C31H41N5O2Purezza:98%Colore e forma:SolidPeso molecolare:515.69SX-517
CAS:SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.Formula:C19H16BFN2O3SColore e forma:SolidPeso molecolare:382.22SA72
CAS:SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).Formula:C21H26N2O6Purezza:98%Colore e forma:SolidPeso molecolare:402.44rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purezza:99.6%Colore e forma:SolidPeso molecolare:605.58FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formula:C24H23N3O3S3Purezza:99.6%Colore e forma:SolidPeso molecolare:497.65Ref: TM-T11256
1mg40,00€5mg90,00€10mg131,00€25mg215,00€50mg309,00€100mg434,00€200mg585,00€1mL*10mM (DMSO)89,00€Elliptinium acetate
CAS:Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.Formula:C20H20N2O3Colore e forma:SolidPeso molecolare:336.38Sulfosuccinimidyl oleate
CAS:Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formula:C22H37NO7SPurezza:98%Colore e forma:SolidPeso molecolare:459.6Aliskiren fumarate
CAS:Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.Formula:C34H57N3O10Colore e forma:SolidPeso molecolare:667.83ALLO-1
CAS:ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formula:C17H15ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:314.77Ipsalazide
CAS:<p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>Formula:C16H11N3Na2O6Purezza:99.43%Colore e forma:SolidPeso molecolare:387.25AS1708727
CAS:AS1708727 inhibits Foxo1, reducing blood sugar and triglycerides by altering gene expression.Formula:C24H24Cl2N2O2Colore e forma:SolidPeso molecolare:443.37CXCR3 Antagonist 6c
CAS:CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.Formula:C30H32Cl3N5O3Colore e forma:SolidPeso molecolare:616.97CC214-2
CAS:CC214-2: strong dual mTORC1/2 inhibitor, blocks autophagy, may shorten TB duration.Formula:C20H25N5O3Colore e forma:SolidPeso molecolare:383.44ATG7-IN-2
CAS:ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.Formula:C11H16N6O7SColore e forma:SolidPeso molecolare:376.35AC-55649
CAS:AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.Formula:C21H26O2Purezza:99.98%Colore e forma:SolidPeso molecolare:310.43HF51116
CAS:HF51116 blocks XCR4, hinders SDF-1α cell effects & HIV-1; potential for HIV, stem cells, cancer spread.Formula:C29H46N8OColore e forma:SolidPeso molecolare:522.73STK683963
CAS:STK683963 activates ATG4B, mediates redox regulation, and aids cancer research.Formula:C12H8FN3O2SColore e forma:SolidPeso molecolare:277.27Obatoclax
CAS:Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.Formula:C20H19N3OPurezza:99.44%Colore e forma:SolidPeso molecolare:317.38KSI-3716
CAS:KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.Formula:C17H11BrCl2N2O2Purezza:98.94%Colore e forma:SolidPeso molecolare:426.09MOPIPP
CAS:MOPIPP: crosses blood-brain barrier, fights glioblastoma, induces vacuolization, boosts autophagy, triggers methuosis, hinders glucose metabolism.Formula:C20H20N2O2Colore e forma:SolidPeso molecolare:320.39CXCR4 antagonist 8
CAS:CXCR4 antagonist 8 (Compound 3) blocks CXCR4, IC50 of 57 nM; stops CXCL12-induced Ca2+ increase, IC50 of 0.24 nM; hinders cell migration.Formula:C21H26N6Colore e forma:SolidPeso molecolare:362.47Antiproliferative agent-5
CAS:Compound 4o inhibits gastric cancer growth, blocks G2/M cell cycle, induces ROS, and triggers autophagy. Used in anti-cancer studies.Formula:C28H21BrN8OSColore e forma:SolidPeso molecolare:597.49AUTEN-67
CAS:AUTEN-67 inhibits MTMR14, boosts autophagy, has antiaging/neuroprotective properties, and combats Huntington's disease onset/severity.Formula:C23H14N4O6SColore e forma:SolidPeso molecolare:474.45Levomepromazine Maleate
CAS:Levomepromazine Maleate: TCA and SNRI with antihistamine, antiadrenergic, and anticholinergic properties.Formula:C23H28N2O5SColore e forma:SolidPeso molecolare:444.546VUF11211
CAS:VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.Formula:C26H35Cl2N5OPurezza:98%Colore e forma:SolidPeso molecolare:504.498-Nitro-cGMP
CAS:8-Nitro-cGMP is a unique cytoprotective mediator which inhibits oxidative stress. 8-Nitro-cGMP is also a probe of the protein S-guanylation.Formula:C10H11N6O9PColore e forma:SolidPeso molecolare:390.20CXCR4 antagonist 9
CAS:CXCR4 antagonist 9, with IC50s of 15 nM & 1.3 nM against CXCR4 & Ca²⁺ rise by CXCL12 respectively.Formula:C21H27FN6Colore e forma:SolidPeso molecolare:382.48Autophagy-IN-C1
CAS:Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea.Formula:C29H28F6N4O2Colore e forma:SolidPeso molecolare:578.55SB-332235
CAS:SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.Formula:C13H10Cl3N3O4SColore e forma:SolidPeso molecolare:410.66Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurezza:99.84%Colore e forma:Clear In WaterPeso molecolare:367.4ICT5040
CAS:ICT5040 is a CXCR4 antagonist.Formula:C10H8F3N3OSColore e forma:SolidPeso molecolare:275.25Norswertianin
CAS:Norswertianin, a xanthone, induces GBM cell differentiation and autophagy via oxidative stress and Akt/mTOR.Formula:C13H8O6Colore e forma:SolidPeso molecolare:260.2PF 750
CAS:PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.Formula:C22H23N3OPurezza:99.87%Colore e forma:SolidPeso molecolare:345.44Ref: TM-T16515
2mg39,00€5mg62,00€10mg87,00€25mg187,00€50mg298,00€100mg444,00€200mg635,00€500mg938,00€1mL*10mM (DMSO)67,00€Dilmapimod tosylate
CAS:Dilmapimod tosylate, a p38 MAPK inhibitor, targets IL-1β, was in phase III trials by GlaxoSmithKline for rheumatoid arthritis and more.Formula:C30H27F3N4O6SColore e forma:SolidPeso molecolare:628.62Quinacrine analog 34
CAS:Quinacrine: anti-protozoal, autophagy inhibitor (toxic at 2.5 μM). Analog 34 less toxic (LD50 = 27 μM), raises LC3-II protein, deacidifies lysosomes.Formula:C20H27ClN4Colore e forma:SolidPeso molecolare:358.91SMYD3-IN-2
SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.Formula:C26H21BrN2O4Colore e forma:SolidPeso molecolare:505.36CXCR4 modulator-2
CAS:CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.Formula:C21H32N8O2Colore e forma:SolidPeso molecolare:428.53NSC 33994
CAS:NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.Formula:C28H42N2O2Purezza:98%Colore e forma:SolidPeso molecolare:438.65SR 3677 dihydrochloride
CAS:Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).Formula:C22H26Cl2N4O4Colore e forma:SolidPeso molecolare:481.37Glaucocalyxin B
CAS:Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).Formula:C22H30O5Purezza:99.13% - 99.35%Colore e forma:SolidPeso molecolare:374.47Ref: TM-TQ0309
1mg97,00€5mg235,00€10mg354,00€25mg582,00€50mgPrezzo su richiesta1mL*10mM (DMSO)243,00€Lamotrigine isethionate
CAS:Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.Formula:C11H13Cl2N5O4SColore e forma:SolidPeso molecolare:382.22PF-06371900
CAS:PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).Formula:C17H16N6O2SColore e forma:SolidPeso molecolare:368.41Ralimetinib
CAS:Ralimetinib blocks MK2 phosphorylation at Thr334 without affecting p38α MAPK or JNK. It is an ATP-competitive inhibitor of p38 MAPK α/β (IC50 5.3/3.2 nM).Formula:C24H29FN6Purezza:99.16% - 99.21%Colore e forma:SolidPeso molecolare:420.53Ivacaftor benzenesulfonate
CAS:Ivacaftor benzenesulfonate used for cystic fibrosis treatment. is an orally bioavailable CFTR potentiator.Formula:C30H34N2O6SPurezza:98%Colore e forma:SolidPeso molecolare:550.67PF-06455943
CAS:PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.Formula:C17H14FN5OColore e forma:SolidPeso molecolare:323.32Poloppin
CAS:Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.Formula:C20H15BrF3NO2Purezza:98%Colore e forma:SolidPeso molecolare:438.24AMD 3465
CAS:AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formula:C24H38N6Purezza:98%Colore e forma:SolidPeso molecolare:410.60Fluoxetine oxalate
CAS:Fluoxetine oxalate, an SSRI, treats depression, OCD, bulimia, panic, and PMS.Formula:C19H20F3NO5Colore e forma:SolidPeso molecolare:399.36Nicodicosapent
CAS:Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.Formula:C28H39N3O2Purezza:98%Colore e forma:SolidPeso molecolare:449.63GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Formula:C24H35N3O4Purezza:99.37%Colore e forma:SolidPeso molecolare:429.55Xantocillin
CAS:Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.Formula:C18H12N2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.3Methophenazine diethanesulfonate
CAS:Methophenazine diethanesulfonate is a Calmodulin antagonist.Formula:C35H48ClN3O11S3Colore e forma:SolidPeso molecolare:818.41Olacaftor
CAS:Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).Formula:C29H34FN3O4SColore e forma:SolidPeso molecolare:539.66CXCR4 antagonist 5
CAS:CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.Formula:C21H30N6Colore e forma:SolidPeso molecolare:366.5CUR5g
CAS:CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formula:C22H20N2O2Purezza:98.92%Colore e forma:SolidPeso molecolare:344.41Ref: TM-T73550
1mg92,00€5mg216,00€10mg344,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)240,00€Ambroxol-d5
CAS:Ambroxol-d5 is a standard for quantifying ambroxol in GC/LC-MS, an expectorant metabolite of bromhexine improving mucociliary functions.Formula:C13H13Br2D5N2OPeso molecolare:383.13p38 MAPK-IN-2
CAS:p38 MAPK-IN-2 is an inhibitor of p38 kinase.Formula:C20H19ClFN5O2Purezza:98%Colore e forma:SolidPeso molecolare:415.85(3S,5R)-Rosuvastatin
CAS:(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).Formula:C22H28FN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:481.54Ivacaftor hydrate
CAS:Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.Formula:C24H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:410.514Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purezza:97.94% - 98.04%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:354.48Ref: TM-T15133
5mg51,00€10mg79,00€25mg144,00€50mg216,00€100mg344,00€200mg512,00€1mL*10mM (DMSO)57,00€CP-53631
CAS:CP-53631 is a selective serotonin reuptake inhibitor (SSRI)Formula:C17H19BrClNColore e forma:SolidPeso molecolare:352.7GSK812397
CAS:GSK812397 inhibits X4-tropic HIV-1 with high potency, targeting CXCR4 receptor noncompetitively and showing broad efficacy and good pharmacokinetics.Formula:C24H32N6OColore e forma:SolidPeso molecolare:420.55SMER18
CAS:SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formula:C16H14ClNO2Purezza:97.27%Colore e forma:SolidPeso molecolare:287.74Ref: TM-T16900
1mg133,00€5mg329,00€10mg472,00€25mg914,00€50mg1.415,00€100mg1.882,00€1mL*10mM (DMSO)360,00€MF-095
CAS:MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.Formula:C27H31N3O4SColore e forma:SolidPeso molecolare:493.62
