Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1490 prodotti di "Autofagia"
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SA72
CAS:SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).Formula:C21H26N2O6Purezza:98%Colore e forma:SolidPeso molecolare:402.44FR 167653 free base
CAS:FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.Formula:C24H18FN5O2Purezza:98%Colore e forma:SolidPeso molecolare:427.43eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formula:C25H19Br2ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:602.71HF50731
CAS:HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).Formula:C26H46N4Colore e forma:SolidPeso molecolare:414.67rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purezza:99.6%Colore e forma:SolidPeso molecolare:605.58Rimacalib
CAS:Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).Formula:C22H23FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:394.44SB02024
CAS:SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.Formula:C16H22F3N3O2Colore e forma:SolidPeso molecolare:345.36Elliptinium acetate
CAS:Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.Formula:C20H20N2O3Colore e forma:SolidPeso molecolare:336.38Sulfosuccinimidyl oleate
CAS:Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formula:C22H37NO7SPurezza:98%Colore e forma:SolidPeso molecolare:459.6LRRK2-IN-10
CAS:LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2Formula:C20H15N5OPurezza:98%Colore e forma:SolidPeso molecolare:341.37SA 47
CAS:SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.Formula:C17H26N4O3Purezza:98%Colore e forma:SolidPeso molecolare:334.41Ipsalazide
CAS:<p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>Formula:C16H11N3Na2O6Purezza:99.43%Colore e forma:SolidPeso molecolare:387.25Aliskiren fumarate
CAS:Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.Formula:C34H57N3O10Colore e forma:SolidPeso molecolare:667.83FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formula:C24H23N3O3S3Purezza:99.6%Colore e forma:SolidPeso molecolare:497.65Ref: TM-T11256
1mg40,00€5mg90,00€10mg131,00€25mg215,00€50mg309,00€100mg434,00€200mg585,00€1mL*10mM (DMSO)89,00€ALLO-1
CAS:ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formula:C17H15ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:314.77BC-1485
CAS:BC-1485 is a small molecule inhibitor of FIEL1 that inhibits the degradation of PIAS4 and ameliorates fibrosis in a mouse model.Formula:C19H21N5O5SPurezza:97.03% - 97.15%Colore e forma:SolidPeso molecolare:431.47AS1708727
CAS:AS1708727 inhibits Foxo1, reducing blood sugar and triglycerides by altering gene expression.Formula:C24H24Cl2N2O2Colore e forma:SolidPeso molecolare:443.37CXCR3 Antagonist 6c
CAS:CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.Formula:C30H32Cl3N5O3Colore e forma:SolidPeso molecolare:616.97FKBP51F67V-selective antagonist Ligand2
CAS:FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 orFormula:C43H56N2O10Purezza:98%Colore e forma:SolidPeso molecolare:760.91GPP78
CAS:GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.Formula:C27H29N5OPurezza:98%Colore e forma:SolidPeso molecolare:439.55
