Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1492 prodotti di "Autofagia"
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Lucanthone hydrochloride
CAS:Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.Formula:C20H25ClN2OSColore e forma:SolidPeso molecolare:376.94Cucurbitacin E
CAS:Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.Formula:C32H44O8Purezza:98.88% - 99.87%Colore e forma:SolidPeso molecolare:556.69Ref: TM-T5S1467
1mg56,00€5mg109,00€10mg168,00€25mg284,00€50mg423,00€100mg610,00€1mL*10mM (DMSO)133,00€Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purezza:97.08% - 99.06%Colore e forma:SolidPeso molecolare:462.54Ref: TM-T1961
1mg34,00€5mg71,00€10mg111,00€25mg170,00€50mg225,00€100mg358,00€200mg530,00€1mL*10mM (DMSO)79,00€Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
Formula:C51H82O21Purezza:99.51% - 99.63%Colore e forma:SolidPeso molecolare:1031.18DBEQ
CAS:DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formula:C22H20N4Purezza:98.93% - ≥95%Colore e forma:SolidPeso molecolare:340.42Ref: TM-T1969
2mg34,00€5mg52,00€10mg85,00€25mg152,00€50mg264,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)52,00€UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purezza:98.31%Colore e forma:SolidPeso molecolare:247.29Ref: TM-T7679
1mg38,00€5mg77,00€10mg110,00€25mg215,00€50mg306,00€100mg429,00€200mg600,00€1mL*10mM (DMSO)95,00€Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purezza:99.16% - 99.84%Colore e forma:SolidPeso molecolare:284.24Ref: TM-T1805
5mg35,00€10mg54,00€25mg88,00€50mg117,00€100mg178,00€200mg213,00€500mg359,00€1mL*10mM (DMSO)46,00€SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurezza:98.84%Colore e forma:SolidPeso molecolare:469.56BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:207.25Ref: TM-T1902
5mg48,00€10mg54,00€25mg90,00€50mg161,00€100mg251,00€200mg378,00€500mg627,00€1mL*10mM (DMSO)50,00€L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurezza:≥95%Colore e forma:SolidPeso molecolare:347.8Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4·HClPurezza:99.28% - 99.98%Colore e forma:White Crystalline Granular OdorlessPeso molecolare:299.66BL-918
CAS:BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formula:C23H15F8N3OSPurezza:99.4% - 99.89%Colore e forma:SolidPeso molecolare:533.44Ref: TM-T8322
1mg50,00€2mg66,00€5mg99,00€10mg147,00€25mg269,00€50mg432,00€100mg708,00€500mg1.423,00€1mL*10mM (DMSO)120,00€TPEN
CAS:TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.Formula:C26H28N6Purezza:98% - 99.72%Colore e forma:White Crystalline PowderPeso molecolare:424.54RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purezza:99.30%Colore e forma:SolidPeso molecolare:312.37Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purezza:99.04% - >99.99%Colore e forma:SolidPeso molecolare:228.2Cryptotanshinone
CAS:Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formula:C19H20O3Purezza:97.94% - ≥95%Colore e forma:Orange Needle CrystalPeso molecolare:296.36Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurezza:98.91% - 99.96%Colore e forma:SolidPeso molecolare:533.95GSK2606414
CAS:GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.Formula:C24H20F3N5OPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:451.44(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurezza:97.57% - 99.97%Colore e forma:SolidPeso molecolare:456.99Ref: TM-T2110
1mg34,00€2mg42,00€5mg57,00€10mg74,00€25mg90,00€50mg137,00€100mg178,00€200mg268,00€500mg485,00€1mL*10mM (DMSO)63,00€Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purezza:98.8% - 99.33%Colore e forma:SolidPeso molecolare:418.35
