Recettore dell'endotelina
I recettori dell'endotelina sono GPCR che mediano gli effetti delle endoteline, potenti peptidi vasocostrittori che giocano un ruolo significativo nella regolazione del tono vascolare, nel controllo della pressione sanguigna e nella proliferazione cellulare. Gli antagonisti dei recettori dell'endotelina sono utilizzati nel trattamento di condizioni come l'ipertensione arteriosa polmonare e l'insufficienza cardiaca. Questi recettori sono anche importanti bersagli nella ricerca sulle malattie cardiovascolari e sul cancro. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori dell'endotelina di alta qualità per supportare la tua ricerca in biologia cardiovascolare, oncologia e fisiologia vascolare.
Trovati 86 prodotti di "Recettore dell'endotelina"
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Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:588.27Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purezza:98.26%Colore e forma:SolidPeso molecolare:2546.92Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Formula:C24H20KN5O5SPurezza:99.05%Colore e forma:SolidPeso molecolare:529.61Ref: TM-T36008
1mg55,00€2mg81,00€5mg117,00€10mg187,00€25mg329,00€50mg530,00€100mg718,00€200mg938,00€1mL*10mM (DMSO)140,00€Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurezza:97.00% - 97.02%Colore e forma:SolidPeso molecolare:424.43Ref: TM-T6258
1mg43,00€2mg57,00€5mg92,00€10mg144,00€25mg283,00€50mgPrezzo su richiesta1mL*10mM (DMSO)93,00€TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:447.53ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Formula:C22H24N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:456.51CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Formula:C19H21N3OColore e forma:SolidPeso molecolare:307.39ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Formula:C30H48N2O6Purezza:98%Colore e forma:SolidPeso molecolare:532.71BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColore e forma:SolidPeso molecolare:395.43CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purezza:98%Colore e forma:SolidPeso molecolare:506.5PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Formula:C28H26NaO9Purezza:98%Colore e forma:SolidPeso molecolare:529.497WS 009B
CAS:WS 009B is an antagonist of the endothelin receptor.Formula:C24H25NO11SPurezza:98%Colore e forma:SolidPeso molecolare:535.52Daglutril
CAS:Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.Formula:C31H38N2O6Colore e forma:SolidPeso molecolare:534.64Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purezza:99.75%Colore e forma:SolidPeso molecolare:547.08Avosentan
CAS:<p>Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.</p>Formula:C23H21N5O5SPurezza:98.31% - 99.47%Colore e forma:SolidPeso molecolare:479.51PD-159020
CAS:PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).Formula:C32H25NO8Purezza:98%Colore e forma:SolidPeso molecolare:551.54WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurezza:98%Colore e forma:SolidPeso molecolare:519.52ETA antagonist 1
CAS:ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).Formula:C20H25N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:387.5Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Formula:C18H15NO4Purezza:96.31% - 99.39%Colore e forma:SolidPeso molecolare:309.32FR 139317
CAS:highly potent and selective ETA endothelin receptor antagonistFormula:C33H44N6O5Purezza:98%Colore e forma:SolidPeso molecolare:604.74BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Formula:C17H19N3O3SPurezza:99.73%Colore e forma:SolidPeso molecolare:345.42Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Formula:C28H32N4O5SPurezza:98.07% - 99.6%Colore e forma:SolidPeso molecolare:536.64SB-209670
CAS:SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.Formula:C29H28O9Purezza:98.29% - 99.40%Colore e forma:SolidPeso molecolare:520.53Ref: TM-T34541
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)797,00€Sitaxsentan
CAS:Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.Formula:C18H15ClN2O6S2Purezza:97.99% - 98.71%Colore e forma:SolidPeso molecolare:454.9L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Formula:C28H29NO8SPurezza:98%Colore e forma:SolidPeso molecolare:539.6Clazosentan
CAS:Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.Formula:C25H23N9O6SPurezza:95.39% - >99.99%Colore e forma:SolidPeso molecolare:577.57Ref: TM-T64084
1mg79,00€5mg178,00€10mg279,00€25mg628,00€50mg1.017,00€100mg1.311,00€200mg1.768,00€1mL*10mM (DMSO)230,00€K-8794
CAS:K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.Formula:C36H38N6O6SColore e forma:SolidPeso molecolare:682.789Edonentan hydrate
CAS:Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].Formula:C28H34N4O6SPeso molecolare:554.66Diosuxentan
CAS:Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Formula:C20H21BrN6O7SColore e forma:SolidPeso molecolare:569.39BMS-248360
CAS:BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.Formula:C36H45N5O5SPurezza:98%Colore e forma:SolidPeso molecolare:659.84JKC 302
CAS:JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.Formula:C30H42N6O6Colore e forma:SolidPeso molecolare:582.69Macitentan (n-butyl analogue)
CAS:Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formula:C20H21Br2N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:587.29IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Formula:C36H35N3O4Purezza:99.36%Colore e forma:White Crystalline SolidPeso molecolare:573.68Tezosentan
CAS:Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).Formula:C27H27N9O6SPurezza:98%Colore e forma:SolidPeso molecolare:605.63BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purezza:98.81%Colore e forma:SolidPeso molecolare:641.8Ref: TM-T10595
1mg137,00€2mg188,00€5mg329,00€10mg472,00€25mg753,00€50mg1.017,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)360,00€Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purezza:98%Colore e forma:LiquidRef: TM-T81538
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