Recettore dell'endotelina
I recettori dell'endotelina sono GPCR che mediano gli effetti delle endoteline, potenti peptidi vasocostrittori che giocano un ruolo significativo nella regolazione del tono vascolare, nel controllo della pressione sanguigna e nella proliferazione cellulare. Gli antagonisti dei recettori dell'endotelina sono utilizzati nel trattamento di condizioni come l'ipertensione arteriosa polmonare e l'insufficienza cardiaca. Questi recettori sono anche importanti bersagli nella ricerca sulle malattie cardiovascolari e sul cancro. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori dell'endotelina di alta qualità per supportare la tua ricerca in biologia cardiovascolare, oncologia e fisiologia vascolare.
Trovati 86 prodotti di "Recettore dell'endotelina"
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Atrasentan sodium
CAS:Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.Formula:C29H37N2NaO6Colore e forma:SolidPeso molecolare:532.61Ro 46-2005
CAS:Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).Formula:C23H27N3O6SPurezza:98.02% - 98.8%Colore e forma:SolidPeso molecolare:473.54RO 46-8443
CAS:RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.Formula:C31H35N3O8SPurezza:98.77% - 99.77%Colore e forma:SolidPeso molecolare:609.69Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Formula:C27H29N5O6S·H2OPurezza:99.31% - 99.86%Colore e forma:White PowderPeso molecolare:569.63Ambrisentan
CAS:Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.Formula:C22H22N2O4Purezza:99.65% - 99.86%Colore e forma:SolidPeso molecolare:378.42Atrasentan
CAS:Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.Formula:C29H38N2O6Purezza:97.65% - 99.08%Colore e forma:SolidPeso molecolare:510.62Ref: TM-TQ0259
1mg46,00€5mg90,00€1mL*10mM (DMSO)109,00€10mg130,00€25mg250,00€50mg356,00€100mg580,00€200mg798,00€Aprocitentan
CAS:Aprocitentan (ACT-132577) is ETA and ETB antagonist .Formula:C16H14Br2N6O4SPurezza:99.17%Colore e forma:SolidPeso molecolare:546.19Ref: TM-T7817
1mg55,00€5mg110,00€1mL*10mM (DMSO)135,00€10mg166,00€25mg295,00€50mg416,00€100mg622,00€200mg840,00€Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Formula:C32H40N4O5SPurezza:97.94% - 98.69%Colore e forma:SolidPeso molecolare:592.75Ref: TM-T5355
2mg37,00€5mg55,00€1mL*10mM (DMSO)73,00€10mg89,00€25mg161,00€50mg245,00€100mg360,00€200mg512,00€BMS 182874 hydrochloride
CAS:BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.Formula:C17H20ClN3O3SPurezza:97.01%Colore e forma:SolidPeso molecolare:381.88Ref: TM-T21790
1mg77,00€2mg92,00€5mg140,00€1mL*10mM (DMSO)146,00€10mg205,00€25mg343,00€50mg477,00€100mg665,00€200mg897,00€ANP(1-28) Acetate (human, porcine)
CAS:Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.Formula:C129H207N45O41S3Purezza:98.24%Colore e forma:SolidPeso molecolare:3140.5Ref: TM-TP1220L
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.388,00€100mg1.872,00€200mg2.527,00€Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:588.27Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purezza:98.26%Colore e forma:SolidPeso molecolare:2546.92Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Formula:C24H20KN5O5SPurezza:99.05%Colore e forma:SolidPeso molecolare:529.61Ref: TM-T36008
1mg52,00€2mg77,00€5mg111,00€1mL*10mM (DMSO)133,00€10mg177,00€25mg313,00€50mg502,00€100mg680,00€200mg888,00€Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurezza:97.00% - 97.02%Colore e forma:SolidPeso molecolare:424.43Ref: TM-T6258
50mgPrezzo su richiesta1mg40,00€2mg54,00€5mg87,00€1mL*10mM (DMSO)87,00€10mg137,00€25mg268,00€TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:447.53ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Formula:C22H24N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:456.51CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Formula:C19H21N3OColore e forma:SolidPeso molecolare:307.39ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Formula:C30H48N2O6Purezza:98%Colore e forma:SolidPeso molecolare:532.71BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColore e forma:SolidPeso molecolare:395.43CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purezza:98%Colore e forma:SolidPeso molecolare:506.5
