Recettore della bombesina
I recettori della bombesina sono un gruppo di GPCR attivati da peptidi simili alla bombesina, coinvolti nella regolazione della funzione gastrointestinale, dell'equilibrio energetico e della proliferazione cellulare. Questi recettori sono di particolare interesse nella ricerca sul cancro, poiché sono spesso sovraespressi in alcuni tipi di tumori. Gli antagonisti dei recettori della bombesina sono studiati per il loro potenziale come terapie contro il cancro. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori della bombesina di alta qualità per supportare la tua ricerca in oncologia, fisiologia gastrointestinale e segnalazione dei recettori.
Trovati 35 prodotti di "Recettore della bombesina"
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CD80-IN-3
CAS:CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).Formula:C17H10FN3O3Purezza:98.08%Colore e forma:SolidPeso molecolare:323.28Ici 216140
CAS:ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.Formula:C45H65N13O8Colore e forma:SolidPeso molecolare:916.08AMTG-DA1
AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.Formula:C101H149IN22O25Colore e forma:SolidPeso molecolare:2197.0109RC-3095
CAS:RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.Formula:C56H79N15O9Purezza:98%Colore e forma:SolidPeso molecolare:1106.32BA 1
CAS:Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.Formula:C57H76N14O11Purezza:98%Colore e forma:SolidPeso molecolare:1133.32PSMA/GRPR ligand 1
PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).Colore e forma:Odour Solid[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.Formula:C79H109N19O12Purezza:98%Colore e forma:SolidPeso molecolare:1516.85[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Formula:C74H112N22O18SPurezza:98%Colore e forma:SolidPeso molecolare:1629.88RC-3095 TFA
CAS:RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.Formula:C58H80F3N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1220.34[D-Phe12,Leu14]-Bombesin
CAS:Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.Formula:C77H113F3N22O20Purezza:98%Colore e forma:SolidPeso molecolare:1724.9GB-6
CAS:GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due toFormula:C32H45N11O8Purezza:98%Colore e forma:SolidPeso molecolare:711.77GRP (14-27) (human, porcine, canine)
CAS:<p>GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not</p>Formula:C75H110N24O16S2Purezza:98%Colore e forma:SolidPeso molecolare:1667.96Gastrin-Releasing Peptide, human
CAS:Gastrin-releasing peptide, released by vagal fibers, stimulates stomach G cells to secrete gastrin, affecting acid secretion and gut motility.Formula:C130H204N38O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2859.38(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:<p>(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].</p>Formula:C49H69N13O9Colore e forma:SolidPeso molecolare:984.15BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.Formula:C59H77F3N14O13Colore e forma:SolidPeso molecolare:1247.32Biotin-Gastrin Releasing Peptide, human TFA
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated form of the gastrin-releasing peptide (GRP). GRP is a neuropeptide known for its growth-stimulating and tumorigenic properties.Colore e forma:Odour SolidNOTA-P2-RM26
CAS:NOTA-P2-RM26 is a high-affinity NOTA-conjugated bombesin antagonist designed for GRPR-targeted tumor imaging.Formula:C73H110N18O19Peso molecolare:1543.76PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Formula:C32H36N6O5Purezza:99.00%Colore e forma:SolidPeso molecolare:584.67Bombesin
CAS:Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.Formula:C71H110N24O18SColore e forma:While Lyophilized PowderPeso molecolare:1619.85ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Formula:C32H35N5O5Purezza:98.62% - >99.99%Colore e forma:SolidPeso molecolare:569.65Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Formula:C53H72N14O13SPurezza:98.61%Colore e forma:SolidPeso molecolare:1145.29Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purezza:97.09% - 97.99%Colore e forma:SolidPeso molecolare:760.82Bombesin acetate(31362-50-2 free base)
CAS:<p>Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).</p>Formula:C73H114N24O20SPurezza:98.44%Colore e forma:SolidPeso molecolare:1679.92BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Formula:C59H80N14O13Purezza:95.3%Colore e forma:SolidPeso molecolare:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C77H118N22O20Purezza:98.41% - 99.14%Colore e forma:SolidPeso molecolare:1671.9[D-Phe12]-Bombesin acetate
<p>[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.</p>Formula:C76H116N22O20SPurezza:99.81%Colore e forma:SolidPeso molecolare:1689.94kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Formula:C40H36O11Purezza:98% - 99.57%Colore e forma:SolidPeso molecolare:692.71Litorin
CAS:Litorin suppresses appetite and stimulates smooth muscle, gastrin, gastric acid, and pancreatic secretion.Formula:C51H68N14O11SColore e forma:White PowderPeso molecolare:1085.24MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Formula:C20H18F6N4OPurezza:98.56%Colore e forma:SolidPeso molecolare:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purezza:98%Colore e forma:SolidPeso molecolare:440.45Bag-1
CAS:Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.Formula:C22H27N3Colore e forma:SolidPeso molecolare:333.47PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Formula:C31H34N6O4Purezza:98.11% - 99.87%Colore e forma:SolidPeso molecolare:554.64PD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Formula:C37H47N5O2Purezza:98%Colore e forma:SolidPeso molecolare:593.8GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Colore e forma:SolidPeso molecolare:558.59GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Colore e forma:SolidPeso molecolare:559.58
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