Recettore della bombesina
I recettori della bombesina sono un gruppo di GPCR attivati da peptidi simili alla bombesina, coinvolti nella regolazione della funzione gastrointestinale, dell'equilibrio energetico e della proliferazione cellulare. Questi recettori sono di particolare interesse nella ricerca sul cancro, poiché sono spesso sovraespressi in alcuni tipi di tumori. Gli antagonisti dei recettori della bombesina sono studiati per il loro potenziale come terapie contro il cancro. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori della bombesina di alta qualità per supportare la tua ricerca in oncologia, fisiologia gastrointestinale e segnalazione dei recettori.
Trovati 37 prodotti per "Recettore della bombesina".
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PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Formula:C32H36N6O5Purezza:99.00%Colore e forma:SolidPeso molecolare:584.67[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C76H116N22O20SPurezza:99.81%Colore e forma:SolidPeso molecolare:1689.94Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Formula:C53H72N14O13SPurezza:98.61%Colore e forma:SolidPeso molecolare:1145.29ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Formula:C32H35N5O5Purezza:98.62% - >99.99%Colore e forma:White SolidPeso molecolare:569.65Ref: TM-T4540
1mg34,00€5mg60,00€1mL*10mM (DMSO)75,00€10mg96,00€25mg170,00€50mg264,00€100mg425,00€200mg587,00€Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purezza:97.09% - 97.99%Colore e forma:Orange SolidPeso molecolare:760.82BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Formula:C59H80N14O13Purezza:99.98%Colore e forma:White SolidPeso molecolare:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C77H118N22O20Purezza:96.99%Colore e forma:White SolidPeso molecolare:1671.9kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Formula:C40H36O11Purezza:98% - 99.57%Colore e forma:Yellow SolidPeso molecolare:692.71Ref: TM-T3S1612
1mg63,00€5mg138,00€1mL*10mM (DMSO)178,00€10mg198,00€25mg321,00€50mg465,00€100mg627,00€200mg845,00€MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Formula:C20H18F6N4OPurezza:98.56%Colore e forma:SolidPeso molecolare:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purezza:98%Colore e forma:SolidPeso molecolare:440.45Bag-1
CAS:Bag-1 is a BRS-3 agonist (EC₅₀=2.5 nM).Formula:C22H27N3Purezza:99.73%Colore e forma:Yellow SolidPeso molecolare:333.47PD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Formula:C37H47N5O2Purezza:98%Colore e forma:SolidPeso molecolare:593.8PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Formula:C31H34N6O4Purezza:98.11% - 99.87%Colore e forma:White SolidPeso molecolare:554.64Ref: TM-T8691
1mg84,00€5mg167,00€1mL*10mM (DMSO)197,00€10mg245,00€25mg492,00€50mg737,00€100mg1.054,00€GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Colore e forma:SolidPeso molecolare:558.59PD 168368 derivative-1
CAS:PD 168368 derivative-1 (Compound 16) is a derivative of PD 168368, exhibiting Ki values of 0.46 nM and 3.7 nM for bombesin receptor subtypes (BB₁ and BB₂) respectively. This compound can be utilized in the study of various diseases such as cancer, depression, and eating disorders.Formula:C33H37N5O5Peso molecolare:583.69GRPR antagonist-3
CAS:GRPR antagonist-3 (compound (S)-1m) is a potent GRPR antagonist with an IC50 of 121 nM. It is stable in rat plasma and exhibits strong resistance to oxidative metabolism by microsomes in vitro. Additionally, GRPR antagonist-3 can be radiolabeled with fluorine-18 for use in PET imaging.Formula:C33H37FN6O5Peso molecolare:616.69GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Colore e forma:SolidPeso molecolare:559.58
![[D-Phe12]-Bombesin acetate](https://static.cymitquimica.com/products/TM/thumb-webp/TP2239L.webp)
![[D-Phe12,Leu14]-Bombesin acetate](https://static.cymitquimica.com/products/TM/thumb-webp/TP1916L1.webp)
