Recettore dell'istamina
I recettori dell'istamina sono GPCR che mediano gli effetti dell'istamina, un'ammina biogena coinvolta nelle risposte immunitarie, nella secrezione acida gastrica e nella neurotrasmissione. Esistono quattro sottotipi di recettori dell'istamina (H1, H2, H3 e H4), ognuno dei quali svolge ruoli distinti nelle reazioni allergiche, nella funzione gastrica e nell'attività del sistema nervoso centrale. Gli antagonisti dei recettori dell'istamina sono ampiamente utilizzati nel trattamento delle allergie, delle ulcere peptiche e della cinetosi. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori dell'istamina di alta qualità per supportare la tua ricerca in immunologia, gastroenterologia e neurofarmacologia.
Trovati 385 prodotti di "Recettore dell'istamina"
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Bamirastine
CAS:Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect onFormula:C31H37N5O3Purezza:96.68%Colore e forma:SolidPeso molecolare:527.66CP-66948
CAS:CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.Formula:C13H20N6SPurezza:99.14%Colore e forma:SolidPeso molecolare:292.4PF-03654764
CAS:PF-03654764, an oral H3 receptor blocker, Ki: human 1.2 nM, rat 7.9 nM, used with Fexofenadine for allergic rhinitis.Formula:C20H28F2N2OPurezza:>99.99%Colore e forma:SolidPeso molecolare:350.45Lavoltidine
CAS:Lavoltidine (Loxtidine) is potent and selective H2 receptor antagonist, oral and irreversible,inhibits gastric acid secretion, gastroesophageal reflux disease.Formula:C19H29N5O2Purezza:98.30% - 98.36%Colore e forma:SolidPeso molecolare:359.47H3R-IN-1 Hydrochloride
CAS:H3R-IN-1 Hydrochloride is an inverse agonist of histamine receptor 3( H3R ) .Formula:C19H24ClN3O3Purezza:98%Colore e forma:SolidPeso molecolare:377.86Propiomazine HCl
CAS:Propiomazine HCl is an analgesia adjunct.Formula:C20H25ClN2OSColore e forma:SolidPeso molecolare:376.94Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Formula:C17H22Cl2N4OPurezza:98.28% - 99.30%Colore e forma:SolidPeso molecolare:369.29JNJ 10191584 maleate
CAS:JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM).Formula:C17H19ClN4O5Purezza:99.37%Colore e forma:SolidPeso molecolare:394.81Azatadine
CAS:Azatadine is histamine and cholinergic inhibitor (IC50: 6.5 nM and 10 nM, respectively).Formula:C20H22N2Purezza:98%Colore e forma:SolidPeso molecolare:290.4Impromidine
CAS:Impromidine is a highly potent and specific agonist of the histamine H2 receptor.Formula:C14H23N7SPurezza:98%Colore e forma:SolidPeso molecolare:321.44VUF14862
CAS:VUF14862 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Formula:C26H32N4O2Colore e forma:SolidPeso molecolare:432.56Sch 44643
CAS:Sch 44643 is an antagonist of platelet activating factor with oral activity.Formula:C25H22ClN3O2Colore e forma:SolidPeso molecolare:431.91UR-PI376
CAS:UR-PI376 is a selective histamine H4 receptor agonist with low H1/H2 activity and moderate H3 affinity.Formula:C17H22N6SColore e forma:SolidPeso molecolare:342.46Brl 22321
CAS:Brl 22321 is a mast cell stabilizer.Formula:C12H9N3O2Colore e forma:SolidPeso molecolare:227.22BL 6341A
CAS:BL 6341A is related to Tumor data and H2-antagonists or anti-histaminsFormula:C9H14N8OS3Colore e forma:SolidPeso molecolare:346.46(R)-Azelastine
CAS:(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Formula:C22H24ClN3OColore e forma:SolidPeso molecolare:381.9Aceprometazine
CAS:Aceprometazine (1664CB) is an antipsychotic which is orally active. Aceprometazine can be used in psychiatric disorders research, for example, depression [1].Formula:C19H22N2OSColore e forma:SolidPeso molecolare:326.46Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Formula:C25H29N5O9Colore e forma:SolidPeso molecolare:543.53ROS 234 dioxalate
CAS:ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)Formula:C17H19N5O8Purezza:98%Colore e forma:SolidPeso molecolare:421.37Fenspiride-d5
CAS:Fenspiride-d5: internal standard for GC/LC-MS quantification, H1 antagonist, NSAID, anti-inflammatory, selective PDE4,5,3 inhibitor.Formula:C15H15D5N2O2Colore e forma:SolidPeso molecolare:265.36GSK-239512
CAS:GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.Formula:C23H27N3O2Purezza:99.62% - 99.74%Colore e forma:SolidPeso molecolare:377.48S-1-Propenyl-L-cysteine
CAS:S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensiveFormula:C6H11NO2SPurezza:98%Colore e forma:SolidPeso molecolare:161.22Dacemazine
CAS:Dacemazine is used to treat depression.Formula:C16H16N2OSColore e forma:SolidPeso molecolare:284.38VUF14738
CAS:VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Formula:C25H32N4O2Colore e forma:SolidPeso molecolare:420.55Nedocromil
CAS:Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).Formula:C19H17NO7Purezza:95% - 97.34%Colore e forma:SolidPeso molecolare:371.34Dothiepin HCl
CAS:Dothiepin HCl: TCA, SNRI, with antihistamine, antiadrenergic, anticholinergic, and sodium block properties.Formula:C19H22ClNSColore e forma:SolidPeso molecolare:331.9FR-A 19
CAS:FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.Formula:C25H34Cl3F2N5Colore e forma:SolidPeso molecolare:548.93KY 234
CAS:KY 234 is a thromboxane synthetase antagonist.Formula:C33H35N5O2Colore e forma:SolidPeso molecolare:533.676(S)-Azelastine
CAS:(S)-Azelastine is an antihistamine reducing receptors H1R, M1R, M3R, and inhibiting HNEpC cell growth.Formula:C22H24ClN3OColore e forma:SolidPeso molecolare:381.9VUF 8328
CAS:VUF 8328 is an agonist of histamine H(3) receptor.Formula:C7H12N4SPurezza:98%Colore e forma:SolidPeso molecolare:184.26ReN-1869
CAS:ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseasesFormula:C24H27NO2Purezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:361.48Immethridine dihydrobromide
CAS:Immethridine dihydrobromide is a histamine H3 receptor agonist.Formula:C9H11Br2N3Purezza:97.61% - 98.14%Colore e forma:SolidPeso molecolare:321.01Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Formula:C13H16N2OPurezza:99.68%Colore e forma:SolidPeso molecolare:216.28DF-1111301
CAS:DF-1111301 is a novel anti-allergic compound with anti-histamine H1 and anti-PAF activity.Formula:C15H25Cl2N3OPurezza:99.17%Colore e forma:SolidPeso molecolare:334.29Noberastine
CAS:Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.Formula:C17H21N5OPurezza:99.72% - >99.99%Colore e forma:SolidPeso molecolare:311.38KP136
CAS:KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).Formula:C16H18N4O3Purezza:98.3% - 98.61%Colore e forma:SolidPeso molecolare:314.34JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Formula:C22H20ClN5OPurezza:99.82%Colore e forma:SolidPeso molecolare:405.88Pitolisant
CAS:Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.Formula:C17H26ClNOPurezza:99.84%Colore e forma:SolidPeso molecolare:295.85Ref: TM-T60636
5mg48,00€10mg70,00€25mg120,00€50mg188,00€100mg311,00€500mg747,00€1mL*10mM (DMSO)52,00€KSK94
CAS:KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.Formula:C25H26N4OPurezza:99.60%Colore e forma:SolidPeso molecolare:398.5Impromidine hydrochloride
CAS:Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.Formula:C14H26Cl3N7SPurezza:99.82%Colore e forma:SolidPeso molecolare:430.83NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Formula:C23H26F3N3O3Purezza:99.43%Colore e forma:SolidPeso molecolare:449.47Clemastine
CAS:Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.Formula:C21H26ClNOPurezza:99.21%Colore e forma:SolidPeso molecolare:343.89Bavisant
CAS:Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.Formula:C19H27N3O2Purezza:99.21% - 99.65%Colore e forma:SolidPeso molecolare:329.44Ref: TM-TQ0046
1mg43,00€5mg96,00€10mg134,00€25mg221,00€50mg325,00€100mg465,00€500mgPrezzo su richiesta1mL*10mM (DMSO)94,00€Linetastine
CAS:Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.Formula:C35H40N2O6Purezza:99.99%Colore e forma:SolidPeso molecolare:584.7D18024
CAS:<p>D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.</p>Formula:C29H31ClFN3OPurezza:99.86%Colore e forma:SolidPeso molecolare:492.03Enerisant hydrochloride
CAS:Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteinsFormula:C22H31ClN4O3Purezza:99.95%Colore e forma:SolidPeso molecolare:434.96Abt-288
CAS:ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.Formula:C23H24N4OPurezza:98.17% - 98.49%Colore e forma:SolidPeso molecolare:372.46KSK68
CAS:KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.Formula:C23H28N2O2Purezza:99.11%Colore e forma:SolidPeso molecolare:364.48Efletirizine
CAS:Efletirizine (UCB-28754), a histamine blocker and 5-LO inhibitor, aids in topical allergy treatment.Formula:C21H24F2N2O3Purezza:99.39%Colore e forma:SolidPeso molecolare:390.42Antihistamine-1
CAS:Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。Formula:C23H24FN5Purezza:99.69%Colore e forma:SolidPeso molecolare:389.47Ref: TM-T10335
5mg58,00€10mg92,00€25mg177,00€50mg334,00€100mgPrezzo su richiesta1mL*10mM (DMSO)64,00€
