Recettore degli oppioidi
I recettori degli oppioidi sono un gruppo di recettori accoppiati alle proteine G che mediano gli effetti degli oppioidi endogeni ed esogeni. Questi recettori svolgono un ruolo centrale nella modulazione del dolore, nella regolazione dell'umore e nei comportamenti di dipendenza. Gli agonisti e antagonisti dei recettori degli oppioidi sono ampiamente utilizzati nella gestione del dolore e nel trattamento delle dipendenze, nonché nella ricerca sui disturbi neurologici e psichiatrici. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori degli oppioidi di alta qualità per supportare la tua ricerca in neurobiologia, gestione del dolore e terapia delle dipendenze.
Trovati 325 prodotti di "Recettore degli oppioidi"
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IPAG
CAS:IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.Formula:C17H22IN3Purezza:99.65%Colore e forma:SolidPeso molecolare:395.28AT-121
CAS:AT-121 is a dual μ-opioid and neuropeptide receptor partial agonist (Kis 16.49 and 3.67 nM, respectively).Formula:C24H38N4O3SPurezza:98.49% - 99.97%Colore e forma:SolidPeso molecolare:462.65Ref: TM-T37610
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€ADL-5747
CAS:ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletalFormula:C24H28N2O3Purezza:98.94% - 99.74%Colore e forma:SolidPeso molecolare:392.49ICI 204,448
CAS:ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.Formula:C23H27Cl3N2O4Purezza:>99.99%Colore e forma:SolidPeso molecolare:501.83NNC 63-0532
CAS:NNC 63-0532 is a potentnociceptin receptor agonist, Ki=7.3 nM, EC50=305 nM.Formula:C27H29N3O3Purezza:99.53%Colore e forma:SolidPeso molecolare:443.54GR 89696 fumarate
CAS:GR 89696 fumarate is a highly selective κ2 opioid receptor agonist (IC50 = 0.04nM) with anti-pruritchy, anti-injury and neuroprotective effects.Formula:C23H29Cl2N3O7Purezza:99.84%Colore e forma:SolidPeso molecolare:530.4N-Benzylnaltrindole hydrochloride
CAS:δ2 opioid receptor antagonistFormula:C33H33ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:541.08Mu opioid receptor antagonist 7
CAS:Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting µ-opioid receptor (µOR) antagonist with an inhibitory concentration (Formula:C22H27ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:386.91Deltakephalin
CAS:Deltakephalin is a synthetic, potent specific opiate delta receptors agonist.Formula:C34H48N6O10Purezza:98%Colore e forma:SolidPeso molecolare:700.78μ opioid receptor agonist 3
CAS:Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM.Formula:C22H28N2O2Purezza:98%Colore e forma:SolidPeso molecolare:352.47Trap-101 hydrochloride
CAS:nociceptin/orphanin FQ (NOP) receptor antagonistFormula:C24H36ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:434.02μ opioid receptor agonist 1
CAS:μ opioid receptor agonist 1 (Compound H-1a) is an optically pure oxyheterocyclic substituted pyrroloxypyrazole derivative and an MOR receptor agonist that canFormula:C26H38N4OColore e forma:SolidPeso molecolare:422.61FK 33-824
CAS:FK 33-824, a stable synthetic analog of methionine enkephalin, reversible with naloxone.Formula:C29H41N5O7SPurezza:98%Colore e forma:SolidPeso molecolare:603.73DPI-3290
CAS:DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potentFormula:C30H34FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:487.61ADL-08-0011
CAS:ADL-08-0011 is an metabolite of alvimopan.Formula:C23H29NO3Colore e forma:SolidPeso molecolare:367.49MR2034
CAS:MR2034 is an agonist of kappa-Opioid receptor. MR2034 stimulates hypothalamic-pituitary-adrenal axis.Formula:C19H27NO2Colore e forma:SolidPeso molecolare:301.42SNC 162
CAS:SNC 162 is a potent and selective delta-opioid receptor (δ-opioid) agonist with analgesic, antidepressant and antiarrhythmic effects.Formula:C27H37N3OPurezza:98%Colore e forma:SolidPeso molecolare:419.6Naloxonazine
CAS:Naloxonazine, a potent, selective opiate mu-1 (μ1) antagonist, also influences leishmania through the modulation of host coding function.Formula:C38H42N4O6Colore e forma:SolidPeso molecolare:650.76Frakefamide
CAS:Frakefamide: potent analgesic, μ-selective agonist, non-CNS penetrating.Formula:C30H34FN5O5Purezza:98%Colore e forma:SolidPeso molecolare:563.62ADL 08-0011 HCl
CAS:ADL 08-0011, a μ-opioid antagonist with Ki 0.25 nM, is derived from alvimopan by gut microbes and counteracts loperamide effects in rats.Formula:C23H30ClNO3Colore e forma:SolidPeso molecolare:403.947ICI 204448
CAS:ICI 204448 is a potent and peripherally selective κ-opioid agonist.Formula:C23H26Cl2N2O4Colore e forma:SolidPeso molecolare:465.37Ro 48-6791
CAS:Ro 48-6791, a GABA receptor agonist, is used potentially for anesthesia.Formula:C21H25FN6O2Colore e forma:SolidPeso molecolare:412.46Naloxonazine dihydrochloride
CAS:μ1 receptor antagonistFormula:C38H43ClN4O6Purezza:98%Colore e forma:SolidPeso molecolare:687.22CYT-1010
CAS:CYT-1010, a mu-opioid receptor agonist; EC50: β-arrestin, 13.1 nM; cAMP, 0.0053 nM. Extracted from patent WO2013173730A2.Formula:C35H40N6O5Purezza:98%Colore e forma:SolidPeso molecolare:624.73Salvinorin A Carbamate
CAS:Salvinorin A carbamate, a potent κ-opioid receptor (KOR) full agonist, exhibits nearly the same potency as salvinorin A, with EC50 values of 6.2 and 4.5 nM, respectively, for activating the human KOR to augment the binding of [35S]GTPγS. Enhancing biological stability, the addition of a carbamate group to salvinorin A reduces deacetylation.Formula:C22H27NO8Colore e forma:SolidPeso molecolare:433.457R-84760 hydrochloride
CAS:R-84760, a potent κ-opioid receptor agonist, relieves tonic pain via supraspinal/spinal pathways, activating noradrenergic descent.Formula:C19H25Cl3N2OSColore e forma:SolidPeso molecolare:435.84Icalcaprant
CAS:Icalcaprant is a kappa-opioid receptor antagonist [1].Formula:C23H26N4O3Purezza:98%Colore e forma:SolidPeso molecolare:406.48Prodilidine hydrochloride
CAS:Prodilidine hydrochloride is an opioid analgesic.Formula:C15H22ClNO2Colore e forma:SolidPeso molecolare:283.79BNTX maleate
CAS:δ1 opioid receptor antagonistFormula:C31H31NO8Purezza:98%Colore e forma:SolidPeso molecolare:545.58Sunobinop
CAS:Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Formula:C26H33N3O3Colore e forma:SolidPeso molecolare:435.56CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Formula:C28H27FN4O4Colore e forma:SolidPeso molecolare:502.54GNTI dihydrochloride
CAS:κ opioid receptor antagonistFormula:C27H30ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:508.01Mu opioid receptor antagonist 2
Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.57BW 443C
CAS:BW 443C is a selective agonist of mu-opioid receptor.Formula:C33H46N10O10Colore e forma:SolidPeso molecolare:742.791MTI013
MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.Formula:C24H26N6O4SColore e forma:SolidPeso molecolare:494.57σ1 Receptor/μ Opioid receptor modulator 2
CAS:Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.Formula:C23H31N3OPeso molecolare:365.51Daeatal
CAS:Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.Formula:C56H93N19O10Purezza:98%Colore e forma:SolidPeso molecolare:1192.46SB-612111
CAS:SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.Formula:C24H29Cl2NOColore e forma:SolidPeso molecolare:418.40SB-612111 hydrochloride
SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.Formula:C24H30Cl3NOColore e forma:SolidPeso molecolare:454.86RX 809055AX
CAS:RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.Formula:C29H29ClN2O4Colore e forma:SolidPeso molecolare:505SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formula:C26H30N2O5Colore e forma:SolidPeso molecolare:450.53BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Formula:C28H37N3O5Purezza:98%Colore e forma:SolidPeso molecolare:495.61Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.576β-Naltrexol
CAS:6β-Naltrexol is a peripherally selective opioid antagonist that reduces constipation from opioids while minimizing central nervous system effects.Formula:C20H25NO4Purezza:99.933%Colore e forma:SolidPeso molecolare:343.42Mu opioid receptor antagonist 8
CAS:Muopioid Receptor Antagonist 8 (368) serves as an antagonist to the μ-opioid receptor, significantly inhibiting the activation of Gi induced by met-enkephalin at the µOR.
Formula:C36H35N3O4SColore e forma:SolidPeso molecolare:605.75Naltrindole 5′-isothiocyanate
CAS:Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.Formula:C27H25N3O3SColore e forma:SolidPeso molecolare:471.571Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Formula:C40H45Cl2N3O6Purezza:98.17% - 99.88%Colore e forma:SolidPeso molecolare:734.71Ref: TM-T12241
1mg38,00€5mg85,00€10mg120,00€25mg235,00€50mg409,00€100mg652,00€200mg908,00€1mL*10mM (DMSO)124,00€J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Formula:C24H37N3O2Purezza:98%Colore e forma:SolidPeso molecolare:399.57Opioid receptor antagonist 1
CAS:Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.
Formula:C24H29ClF3NO4Colore e forma:SolidPeso molecolare:487.94JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Formula:C28H41Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:538.55
