SGLT
I co-trasportatori sodio-glucosio (SGLT) sono proteine di membrana che facilitano il riassorbimento del glucosio nei reni accoppiando il trasporto del glucosio con gli ioni sodio. Gli inibitori degli SGLT sono una classe importante di farmaci utilizzati nel trattamento del diabete di tipo 2, in quanto aiutano a ridurre i livelli di glucosio nel sangue impedendo il riassorbimento del glucosio nei tubuli renali. Questi inibitori vengono anche studiati per i loro potenziali benefici nella protezione cardiovascolare e renale. Presso CymitQuimica, offriamo una gamma di modulatori SGLT di alta qualità per supportare la tua ricerca sul diabete, la fisiologia renale e i disturbi metabolici.
Trovati 31 prodotti di "SGLT"
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KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Formula:C26H40N4O8Purezza:98.46%Colore e forma:SolidPeso molecolare:536.62Ref: TM-T15656
1mg109,00€2mg158,00€5mg260,00€1mL*10mM (DMSO)305,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€Sergliflozin A
CAS:Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Formula:C20H24O7Purezza:99.71%Colore e forma:SolidPeso molecolare:376.4O-Desethyl Dapagliflozin
CAS:O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Formula:C19H21ClO6Purezza:98.33%Colore e forma:SolidPeso molecolare:380.82Ref: TM-T67849
1mg54,00€5mg114,00€1mL*10mM (DMSO)128,00€10mg177,00€25mg304,00€50mg445,00€100mg647,00€Canagliflozin (Standard)
CAS:Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).Formula:C24H25FO5SColore e forma:SolidPeso molecolare:444.52Sotagliflozin
CAS:Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFormula:C21H25ClO5SPurezza:99% - 99.86%Colore e forma:SolidPeso molecolare:424.94Ref: TM-T3547
1mg43,00€2mg54,00€5mg93,00€1mL*10mM (DMSO)94,00€10mg124,00€25mg235,00€50mg358,00€100mg532,00€500mg1.134,00€Empagliflozin
CAS:Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Formula:C23H27ClO7Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:450.91Ref: TM-T1766
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€50mg74,00€100mg90,00€200mg137,00€500mg178,00€1g263,00€Mizagliflozin
CAS:Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Formula:C28H44N4O8Purezza:98.66% - 99.67%Colore e forma:SolidPeso molecolare:564.67Ref: TM-T16083
1mg63,00€2mg92,00€5mg137,00€1mL*10mM (DMSO)170,00€10mg215,00€25mg432,00€50mg612,00€100mg888,00€200mg1.198,00€Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formula:C21H25ClO6Purezza:99.5% - 99.93%Colore e forma:SolidPeso molecolare:408.87Ref: TM-T2389
5mg47,00€1mL*10mM (DMSO)52,00€10mg60,00€25mg77,00€50mg94,00€100mg107,00€200mg142,00€1500mg284,00€Enavogliflozin
CAS:Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Formula:C24H27ClO6Purezza:97.37%Colore e forma:SolidPeso molecolare:446.92Ref: TM-T38843
1mg147,00€5mg358,00€1mL*10mM (DMSO)394,00€10mg560,00€25mg973,00€50mg1.333,00€100mg1.765,00€Ipragliflozin
CAS:Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.Formula:C21H21FO5SPurezza:99.38% - 99.70%Colore e forma:SolidPeso molecolare:404.45T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formula:C26H28O11Purezza:99.78%Colore e forma:SolidPeso molecolare:516.49Ref: TM-T9590
1mg50,00€2mg71,00€5mg90,00€1mL*10mM (DMSO)127,00€10mg130,00€25mg207,00€50mg370,00€100mg530,00€Phloretin
CAS:Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.Formula:C15H14O5Purezza:98.53% - >99.99%Colore e forma:SolidPeso molecolare:274.27Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Formula:C24H35ClO9Purezza:99.88% - 99.94%Colore e forma:SolidPeso molecolare:502.98Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Formula:C24H25FO5SPurezza:98.01% - >99.99%Colore e forma:SolidPeso molecolare:444.52Ref: TM-T1782
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg63,00€25mg82,00€50mg90,00€100mg116,00€500mg260,00€Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Formula:C21H24O10Purezza:99.73% - 99.77%Colore e forma:Solid CrystallinePeso molecolare:436.41Tofogliflozin (hydrate)
CAS:Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Formula:C22H28O7Purezza:97.03% - 98.78%Colore e forma:SolidPeso molecolare:404.45Ref: TM-T5016
1mg35,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg109,00€25mg202,00€50mg324,00€100mg505,00€200mg717,00€Ertugliflozin
CAS:PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Formula:C22H25ClO7Purezza:99.89% - 99.96%Colore e forma:SolidPeso molecolare:436.88Bexagliflozin
CAS:Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Formula:C24H29ClO7Purezza:98.99% - 99.89%Colore e forma:SolidPeso molecolare:464.94Ref: TM-T7217
1mg67,00€2mg95,00€5mg129,00€1mL*10mM (DMSO)137,00€10mg187,00€25mg371,00€50mg552,00€100mg785,00€Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormula:C21H24O10Purezza:97.16%Colore e forma:SolidPeso molecolare:436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€Canagliflozin hemihydrate
CAS:Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Formula:C48H52F2O11S2Purezza:99.42% - 99.96%Colore e forma:SolidPeso molecolare:907.05
