Recettore della dopamina
I recettori della dopamina sono un gruppo di recettori accoppiati alle proteine G (GPCR) che rispondono al neurotrasmettitore dopamina, svolgendo un ruolo chiave nella regolazione del movimento, della motivazione, della ricompensa e di diverse funzioni cognitive. Questi recettori sono divisi in famiglie simili a D1 e D2, ognuna con funzioni e profili farmacologici distinti. I modulatori dei recettori della dopamina sono ampiamente studiati per le loro applicazioni nel trattamento del morbo di Parkinson, della schizofrenia, della dipendenza e di altri disturbi neuropsichiatrici. Presso CymitQuimica, offriamo una vasta gamma di modulatori dei recettori della dopamina di alta qualità per supportare la tua ricerca in neuroscienze, salute mentale e segnalazione GPCR.
Trovati 444 prodotti di "Recettore della dopamina"
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Medifoxamine
CAS:Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.MedifoxamineFormula:C16H19NO2Purezza:98.88%Colore e forma:SolidPeso molecolare:257.33Ref: TM-T24444
1mg99,00€5mg235,00€10mg354,00€25mg635,00€50mg893,00€100mg1.159,00€1mL*10mM (DMSO)259,00€A-437203
CAS:A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.Formula:C20H27F3N6OSPurezza:98.80%Colore e forma:SolidPeso molecolare:456.53Ref: TM-T10213
1mg94,00€5mg188,00€10mg264,00€25mg411,00€50mg532,00€100mg740,00€200mg982,00€1mL*10mM (DMSO)215,00€BP14979
CAS:BP14979 is D3R-selective partial agonist.Formula:C23H34N4O2Purezza:98.29% - 99.73%Colore e forma:SolidPeso molecolare:398.54SK609 HCl
CAS:SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formula:C10H15Cl2NPurezza:99.02%Colore e forma:SolidPeso molecolare:220.14Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:425.52Ref: TM-T15270
2mg42,00€5mg56,00€10mg81,00€25mg116,00€50mg170,00€100mg250,00€200mg369,00€1mL*10mM (DMSO)62,00€CyPPA
CAS:<p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>Formula:C16H23N5Purezza:99.88%Colore e forma:SolidPeso molecolare:285.39Remoxipride hydrochloride
CAS:Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-Formula:C16H24BrClN2O3Purezza:99.88%Colore e forma:SolidPeso molecolare:407.73CCG 203769
CAS:CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.Formula:C8H14N2O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:202.27Ref: TM-T10705
1mg88,00€5mg187,00€10mg264,00€25mg469,00€50mg657,00€100mg944,00€500mg1.882,00€1mL*10mM (DMSO)207,00€SB-414796
CAS:SB-414796 is a selective antagonist of the dopamine D3 receptor.Formula:C29H36N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:536.69JNJ-37822681 dihydrochloride
CAS:JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。Formula:C17H19Cl2F5N4Purezza:99.78%Colore e forma:SolidPeso molecolare:445.26Dihydrexidine
CAS:Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.Formula:C17H17NO2Purezza:98%Colore e forma:SolidPeso molecolare:267.32Piribedil N-oxide
CAS:Piribedil N-oxide, a metabolite of the dopamine receptor agonist piribedil, represents a chemical compound involved in the metabolic processing of its parent compound, piribedil.Formula:C16H18N4O3Colore e forma:SolidPeso molecolare:314.34CY 208-243
CAS:CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.Formula:C19H18N2Purezza:98%Colore e forma:SolidPeso molecolare:274.36FAUC-312
CAS:FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formula:C21H26N4Purezza:98%Colore e forma:SolidPeso molecolare:334.46Z1078601926
CAS:Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].Formula:C14H19FN2OColore e forma:SolidPeso molecolare:250.31Carmoxirole hydrochloride
CAS:Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.Formula:C24H27ClN2O2Purezza:99.37% - 99.62%Colore e forma:SolidPeso molecolare:410.94Ref: TM-T10683
1mg44,00€5mg90,00€10mg130,00€25mg215,00€50mg316,00€100mg434,00€200mg585,00€1mL*10mM (DMSO)94,00€Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColore e forma:SolidPeso molecolare:412.38Timiperone
CAS:Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior.Formula:C22H24FN3OSPurezza:98%Colore e forma:SolidPeso molecolare:397.51Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36Ref: TM-T14782
1mg105,00€5mg250,00€10mg406,00€25mg700,00€50mg1.008,00€100mg1.378,00€200mg1.833,00€1mL*10mM (DMSO)283,00€LY3154885
CAS:LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).Formula:C23H23Cl2N3O2Colore e forma:SolidPeso molecolare:444.35
