Recettore della dopamina
I recettori della dopamina sono un gruppo di recettori accoppiati alle proteine G (GPCR) che rispondono al neurotrasmettitore dopamina, svolgendo un ruolo chiave nella regolazione del movimento, della motivazione, della ricompensa e di diverse funzioni cognitive. Questi recettori sono divisi in famiglie simili a D1 e D2, ognuna con funzioni e profili farmacologici distinti. I modulatori dei recettori della dopamina sono ampiamente studiati per le loro applicazioni nel trattamento del morbo di Parkinson, della schizofrenia, della dipendenza e di altri disturbi neuropsichiatrici. Presso CymitQuimica, offriamo una vasta gamma di modulatori dei recettori della dopamina di alta qualità per supportare la tua ricerca in neuroscienze, salute mentale e segnalazione GPCR.
Trovati 445 prodotti di "Recettore della dopamina"
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Quinpirole
CAS:Quinpirole is a dopamine D2/D3 receptor agonist.Formula:C13H21N3Colore e forma:SolidPeso molecolare:219.33GBR-13069 dimethanesulfonate
CAS:GBR-13069 dimethanesulfonate is a dopamine reuptake inhibitor.Formula:C30H38F2N2O7S2Colore e forma:SolidPeso molecolare:640.76Oxypertine
CAS:Oxypertine, an indole-derived antipsychotic, treats psychoses like mania, schizophrenia, and severe anxiety, akin to chlorpromazine.Formula:C23H29N3O2Colore e forma:SolidPeso molecolare:379.5Clopenthixol
CAS:Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.Formula:C22H25ClN2OSColore e forma:SolidPeso molecolare:400.96U 101958
CAS:U 101958 is a putative antipsychotic agent It is also a highly selective dopamine D4 receptor antagonist.Formula:C20H27N3OColore e forma:SolidPeso molecolare:325.45Zelandopam free base
CAS:Zelandopam: dopamine D1 agonist, boosts pancreatic secretion, renal vasodilator, counters renal dysfunction.Formula:C15H15NO4Colore e forma:SolidPeso molecolare:273.28Savoxepin mesylate
CAS:Savoxepin mesylate, a tetracyclic cyano-dibenzoxepino-azepine derivative, has potent antidopaminergic activity.Formula:C26H30N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:466.59(R)-PF-06256142
CAS:(R)-PF-06256142: low-activity R enantiomer of a potent, selective D1 agonist reducing receptor desensitization.Formula:C21H16N4O2Colore e forma:SolidPeso molecolare:356.38SV293
CAS:SV293 is a selective antagonist of D2 dopamine receptor.Formula:C22H26N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:382.52Dicarbine
CAS:Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite mid-brain stimulation.Formula:C13H18N2Purezza:98%Colore e forma:SolidPeso molecolare:202.3L-750,667 Trihydrochloride
CAS:L-750,667 Trihydrochloride is a selective D4 receptor antagonist, reverses the dopamine-induced inhibition of cAMP accumulation in the central nervous system.Formula:C18H22Cl3IN4Purezza:99.63%Colore e forma:SolidPeso molecolare:527.666-Chloromelatonin
CAS:6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.Formula:C13H15ClN2O2Purezza:97.26% - 99.25%Colore e forma:SolidPeso molecolare:266.72Ref: TM-T22530
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€A-77636
CAS:A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50Formula:C20H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:329.43D4R agonist-1
CAS:D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.Formula:C19H22N4SPurezza:98.44%Colore e forma:SolidPeso molecolare:338.47PG 01037 dihydrochloride
CAS:PG 01037 dihydrochloride (PG-01037 2HCl) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.Formula:C26H28Cl4N4OPurezza:99.89%Colore e forma:SolidPeso molecolare:554.34SKF83959
CAS:SKF83959: dopamine D1 partial agonist, Ki: D1(1.18 nM), D5(7.56 nM), D2(920 nM), D3(399 nM); improves cognitive function in depression, Alzheimer's.
Formula:C18H20ClNO2Purezza:98.68%Colore e forma:SolidPeso molecolare:317.81WAY-260022
CAS:WAY-260022 is the norepinephrine transporter inhibitor.Formula:C21H31F3N2O2Purezza:97.61% - 99.41%Colore e forma:SolidPeso molecolare:400.48Halopemide
CAS:Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).Formula:C21H22ClFN4O2Purezza:96.57%Colore e forma:SolidPeso molecolare:416.88Benperidol
CAS:Benperidol (Anquil), a butanone derivative, has antipsychotic effects and blocks D2 receptors; useful in PET scans.Formula:C22H24FN3O2Purezza:99.91%Colore e forma:SolidPeso molecolare:381.44Ref: TM-T26360
1mg116,00€5mg276,00€10mg410,00€25mg680,00€50mg938,00€100mg1.293,00€500mg2.593,00€1mL*10mM (DMSO)279,00€PF-00217830
CAS:PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.Formula:C26H30N4O2Purezza:98.72%Colore e forma:SolidPeso molecolare:430.54NGD 94-1
CAS:NGD 94-1 is a D4 receptor antagonist that can be used to study psychiatric disorders such as cognitive impairment.Formula:C18H20N6Purezza:99.61%Colore e forma:SolidPeso molecolare:320.39SB-277011
CAS:SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).Formula:C28H30N4OPurezza:99.39%Colore e forma:SolidPeso molecolare:438.56Ref: TM-T12861
1mg47,00€5mg58,00€10mg93,00€25mg158,00€50mg254,00€100mgPrezzo su richiesta1mL*10mM (DMSO)60,00€Milenperone
CAS:Milenperone (R 34009) is a novel anti-invasive compound for the control of behavioral disorders in patients with epilepsy and alcoholism.Formula:C22H23ClFN3O2Purezza:98.09% - 99.84%Colore e forma:SolidPeso molecolare:415.89U 99194 maleate
CAS:U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.Formula:C21H31NO6Purezza:99.45%Colore e forma:SolidPeso molecolare:393.47PD 168568 dihydrochloride
CAS:PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).Formula:C22H29Cl2N3OPurezza:99.71%Colore e forma:SolidPeso molecolare:422.39Ref: TM-T12383
5mg46,00€10mg55,00€25mg111,00€50mg166,00€100mg235,00€200mg329,00€1mL*10mM (DMSO)57,00€Molindone
CAS:Molindone: antipsychotic for schizophrenia; blocks dopamine, often paired with serotonin; dosage affects error/response rates.Formula:C16H24N2O2Purezza:99.46% - 99.67%Colore e forma:Off-White SolidPeso molecolare:276.37MLS1547
CAS:MLS1547 is a potent D2 receptor G protein-biased agonist (Ki=1.2 μM, EC50=0.37 μM in Ca2+ assay).Formula:C19H19ClN4OPurezza:99.64%Colore e forma:SolidPeso molecolare:354.837-Hydroxy-DPAT hydrobromide
CAS:7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist that blocks dopamine reuptake, used in research on neurological diseases.Formula:C16H26BrNOPurezza:99.73%Colore e forma:SolidPeso molecolare:328.29GBR 12783 dihydrochloride
CAS:GBR 12783 dihydrochloride inhibits dopamine uptake in rats/mice; IC50s: 1.8/1.2 nM. Enhances memory, boosts hippocampal acetylcholine.
Formula:C28H34Cl2N2OPurezza:98.08%Colore e forma:SolidPeso molecolare:485.49Seridopidine
CAS:Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.Formula:C14H20FNO2SPurezza:99.77%Colore e forma:SolidPeso molecolare:285.38Ordopidine
CAS:Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.Formula:C14H20FNO2SPurezza:97.09%Colore e forma:SolidPeso molecolare:285.38Medifoxamine
CAS:Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.MedifoxamineFormula:C16H19NO2Purezza:98.88%Colore e forma:SolidPeso molecolare:257.33Ref: TM-T24444
1mg94,00€5mg222,00€10mg334,00€25mg602,00€50mg845,00€100mg1.099,00€1mL*10mM (DMSO)245,00€A-437203
CAS:A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.Formula:C20H27F3N6OSPurezza:98.80%Colore e forma:SolidPeso molecolare:456.53Ref: TM-T10213
1mg94,00€5mg188,00€10mg264,00€25mg411,00€50mg532,00€100mg740,00€200mg982,00€1mL*10mM (DMSO)215,00€BP14979
CAS:BP14979 is D3R-selective partial agonist.Formula:C23H34N4O2Purezza:98.29% - 99.73%Colore e forma:SolidPeso molecolare:398.54SK609 HCl
CAS:SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formula:C10H15Cl2NPurezza:99.02%Colore e forma:SolidPeso molecolare:220.14Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:425.52Ref: TM-T15270
2mg39,00€5mg52,00€10mg77,00€25mg110,00€50mg166,00€100mg236,00€200mg349,00€1mL*10mM (DMSO)58,00€CyPPA
CAS:CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.
Formula:C16H23N5Purezza:99.88%Colore e forma:SolidPeso molecolare:285.39Remoxipride hydrochloride
CAS:Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-Formula:C16H24BrClN2O3Purezza:99.88%Colore e forma:SolidPeso molecolare:407.73CCG 203769
CAS:CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.Formula:C8H14N2O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:202.27Ref: TM-T10705
1mg84,00€5mg177,00€10mg250,00€25mg444,00€50mg622,00€100mg893,00€500mg1.783,00€1mL*10mM (DMSO)195,00€SB-414796
CAS:SB-414796 is a selective antagonist of the dopamine D3 receptor.Formula:C29H36N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:536.69JNJ-37822681 dihydrochloride
CAS:JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。Formula:C17H19Cl2F5N4Purezza:99.78%Colore e forma:SolidPeso molecolare:445.26Dihydrexidine
CAS:Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.Formula:C17H17NO2Purezza:98%Colore e forma:SolidPeso molecolare:267.32Piribedil N-oxide
CAS:Piribedil N-oxide, a metabolite of the dopamine receptor agonist piribedil, represents a chemical compound involved in the metabolic processing of its parent compound, piribedil.Formula:C16H18N4O3Colore e forma:SolidPeso molecolare:314.34CY 208-243
CAS:CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.Formula:C19H18N2Purezza:98%Colore e forma:SolidPeso molecolare:274.36FAUC-312
CAS:FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formula:C21H26N4Purezza:98%Colore e forma:SolidPeso molecolare:334.46Z1078601926
CAS:Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].Formula:C14H19FN2OColore e forma:SolidPeso molecolare:250.31Carmoxirole hydrochloride
CAS:Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.Formula:C24H27ClN2O2Purezza:99.37% - 99.62%Colore e forma:SolidPeso molecolare:410.94Ref: TM-T10683
1mg44,00€5mg90,00€10mg130,00€25mg215,00€50mg316,00€100mg434,00€200mg585,00€1mL*10mM (DMSO)94,00€Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColore e forma:SolidPeso molecolare:412.38Timiperone
CAS:Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior.Formula:C22H24FN3OSPurezza:98%Colore e forma:SolidPeso molecolare:397.51Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36Ref: TM-T14782
1mg105,00€5mg250,00€10mg406,00€25mg700,00€50mg1.008,00€100mg1.378,00€200mg1.833,00€1mL*10mM (DMSO)283,00€
