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PAFR

PAFR

Il recettore del fattore attivante le piastrine (PAFR) è un GPCR che si lega al fattore attivante le piastrine (PAF), un potente mediatore fosfolipidico coinvolto nell'infiammazione, nella trombosi e nelle risposte allergiche. La segnalazione del PAFR svolge un ruolo cruciale nelle risposte immunitarie, nella salute cardiovascolare e nella patogenesi delle malattie infiammatorie. La modulazione dell'attività del PAFR è di interesse nello sviluppo di terapie antinfiammatorie e antitrombotiche. Presso CymitQuimica, offriamo una varietà di modulatori di PAFR di alta qualità per supportare la tua ricerca in immunologia, biologia cardiovascolare e infiammazione.

Trovati 10 prodotti per "PAFR".

  • 2-Acetylbenzoic acid
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    2-Acetylbenzoic acid

    CAS:
    2-Acetylbenzoic acid outperforms 2-propionyloxybenzoic in hindering platelet function and PG synthesis; both similar in blocking PGI2 creation.
    Formula:C9H8O3
    Purezza:99.62%
    Colore e forma:Off-White Solid
    Peso molecolare:164.158

    Ref: TM-TMA0536

  • Tulopafant
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    Tulopafant

    CAS:
    Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.
    Formula:C25H19N3O2S
    Purezza:99.38%
    Colore e forma:Yellow Solid
    Peso molecolare:425.5

    Ref: TM-T17178

  • PAF-AN-1
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    PAF-AN-1

    CAS:
    PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.
    Formula:C28H28N2O3
    Purezza:98.06%
    Colore e forma:Solid
    Peso molecolare:440.53

    Ref: TM-T14007

  • Rocepafant
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    Rocepafant

    CAS:
    Rocepafant (LAU8080), a PAF antagonist, reduces neonatal rat brain damage and inhibits TNF-α toxicity in L929 cells.
    Formula:C26H23ClN6OS2
    Purezza:97.31% - 98.95%
    Colore e forma:Solid
    Peso molecolare:535.083

    Ref: TM-T28607

  • SDZ-62-434
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    SDZ-62-434

    CAS:
    SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity and may be used in the study of leukemia.
    Formula:C23H27Cl2N3
    Purezza:99.90%
    Colore e forma:Solid
    Peso molecolare:416.39

    Ref: TM-T28740

  • 48740 RP
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    48740 RP

    CAS:
    48740 RP (RP 55779) is an antagonist of platelet-activating factor.
    Formula:C12H11N3OS
    Purezza:99.79%
    Colore e forma:Yellow Solid
    Peso molecolare:245.3

    Ref: TM-T10159

  • Foropafant
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    Foropafant

    CAS:
    Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).
    Formula:C28H40N4S
    Purezza:99.67%
    Colore e forma:Yellow Solid
    Peso molecolare:464.709

    Ref: TM-T15338

  • ST-899
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    ST-899

    CAS:
    ST-899 is an innovative platelet-activating factor (PAF) receptor antagonist. It significantly reduces the mortality rate in mice experiencing shock induced by endotoxins (LPS). The compound markedly inhibits the LPS-induced increase in serum tumor necrosis factor (TNF) levels while leaving interleukin-6 (IL-6) unaffected. The mechanism by which ST-899 operates involves disrupting the positive feedback loop between PAF and TNF, thereby mitigating inflammatory responses. ST-899 is applicable for studies related to inflammatory diseases such as septic shock.
    Formula:C22H29BrClNO6
    Colore e forma:Solid
    Peso molecolare:518.83

    Ref: TM-T211047

  • Logo CymitQuimica
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    SDZ-62-434 free base

    CAS:
    SDZ-62-434 (free base) is a platelet-activating factor (PAF) antagonist with antiproliferative properties against human solid tumors and hematological malignancies.
    Formula:C23H25N3
    Peso molecolare:343.47

    Ref: TM-T213709

  • Apafant
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    Apafant

    CAS:
    Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
    Formula:C22H22ClN5O2S
    Purezza:99.56%
    Colore e forma:White Solid
    Peso molecolare:455.96

    Ref: TM-T14300