Recettore dei cannabinoidi

I recettori dei cannabinoidi sono GPCR che mediano gli effetti dei cannabinoidi endogeni (endocannabinoidi) e fitocannabinoidi, come quelli presenti nella cannabis. I due principali tipi di recettori dei cannabinoidi, CB1 e CB2, sono coinvolti nella regolazione di una vasta gamma di processi fisiologici, tra cui la percezione del dolore, l'appetito, l'umore e la funzione immunitaria. I modulatori dei recettori dei cannabinoidi hanno un potenziale terapeutico nel trattamento di condizioni come il dolore cronico, l'epilessia e la sclerosi multipla. Presso CymitQuimica, offriamo una vasta gamma di modulatori di recettori dei cannabinoidi di alta qualità per supportare la tua ricerca in neurofarmacologia, gestione del dolore e immunologia.

Trovati 216 prodotti di "Recettore dei cannabinoidi"

Purezza (%)

100

prodotti per pagina.

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GW405833 hydrochloride
CAS:
- 1202865-22-2
GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].
Formula:C₂₃H₂₅Cl₃N₂O₃
Colore e forma:Solid
Peso molecolare:483.82
Ref: TM-T84721
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2-Linoleoyl Glycerol
CAS:
- 3443-82-1
2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.
Formula:C₂₁H₃₈O₄
Colore e forma:Solid
Peso molecolare:354.531
Ref: TM-T84648
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GSK494581A
CAS:
- 909416-67-7
GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.
Formula:C₂₇H₂₈F₂N₂O₄S
Purezza:98%
Colore e forma:Solid
Peso molecolare:514.58
Ref: TM-T27480
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PF 514273
CAS:
- 851728-60-4
PF 514273 is a CB1 receptor antagonist.
Formula:C₂₁H₁₇Cl₂F₂N₃O₂
Purezza:98%
Colore e forma:Solid
Peso molecolare:452.28
Ref: TM-T23139
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PSNCBAM-1
CAS:
- 877202-74-9
PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.
Formula:C₂₂H₂₁ClN₄O
Purezza:99.86%
Colore e forma:Solid
Peso molecolare:392.88
Ref: TM-T28468
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Hemopressin(rat) TFA
CAS:
- 1431329-47-3
Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.
Formula:C₅₅H₇₈F₃N₁₃O₁₄
Colore e forma:Solid
Peso molecolare:1202.28
Ref: TM-T75798
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11(Z),14(Z)-Eicosadienoic Acid Ethanolamide
CAS:
- 162758-92-1
11(Z),14(Z)-Eicosadienoic acid ethanolamide is an ethanolamide derivative of 11(Z),14(Z)-eicosadienoic acid.
Formula:C₂₂H₄₁NO₂
Colore e forma:Solid
Peso molecolare:351.57
Ref: TM-T85017
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SAD-448
CAS:
- 581106-09-4
SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.
Formula:C₂₄H₂₈N₄O₈S
Colore e forma:Solid
Peso molecolare:532.57
Ref: TM-T28657
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O-2545 hydrochloride
CAS:
- 874745-43-4
O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.
Formula:C₂₆H₃₆N₂O₂HCl
Colore e forma:Solid
Peso molecolare:445
Ref: TM-T84516
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Tricosanoyl Ethanolamide
CAS:
- 171022-15-4
Tricosanoyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, has an ethanolamine metabolite whose significance remains to be established.
Formula:C₂₅H₅₁NO₂
Colore e forma:Solid
Peso molecolare:397.688
Ref: TM-T84458
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Isopropyl dodec-11-enylfluorophosphonate
CAS:
- 623114-64-7
Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits
Formula:C₁₅H₃₀FO₂P
Purezza:98%
Colore e forma:Solid
Peso molecolare:292.37
Ref: TM-T78674
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MCHB-1
CAS:
- 1046140-32-2
MCHB-1, a potent agonist of the human cannabinoid 2 (CB2) receptor (EC50= 0.52 nM), demonstrates high selectivity for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively), distinguishing itself from similar benzimidazole compounds that significantly alleviate peripheral pain while minimizing central nervous system side effects in mice.
Formula:C₂₈H₃₇N₃O₂
Colore e forma:Solid
Peso molecolare:447.623
Ref: TM-T84442
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CB1 antagonist 1
CAS:
- 890037-68-0
CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and
Formula:C₂₆H₂₂Cl₂N₄
Purezza:98%
Colore e forma:Solid
Peso molecolare:461.39
Ref: TM-T10510
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Amauromine
CAS:
- 88360-87-6
Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.
Formula:C₃₂H₃₆N₄O₂
Colore e forma:Solid
Peso molecolare:508.65
Ref: TM-T36566
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CB 65
CAS:
- 913534-05-1
CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.
Formula:C₂₂H₂₈ClN₃O₃
Purezza:99.53%
Colore e forma:Solid
Peso molecolare:417.93
Ref: TM-T41230
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(R)-Monlunabant
CAS:
- 2765579-76-6
<p>(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].</p>
Formula:C₂₆H₂₂ClF₃N₆O₃S
Purezza:98%
Colore e forma:Solid
Peso molecolare:591
Ref: TM-T83533
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CB1 inverse agonist 1
CAS:
- 852315-00-5
MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.
Formula:C₂₅H₁₈Cl₃N₃O₃
Purezza:99.92%
Colore e forma:Solid
Peso molecolare:514.79
Ref: TM-T10694
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AM841
CAS:
- 871978-21-1
AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.
Formula:C₂₆H₃₉NO₃S
Purezza:98%
Colore e forma:Solid
Peso molecolare:445.66
Ref: TM-T78949
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γ-Linolenoyl monoethanolamide
CAS:
- 150314-37-7
γ-Linolenoyl monoethanolamide, a fatty N-acyl ethanolamine, acts as an endocannabinoid [1] [2].
Formula:C₂₀H₃₅NO₂
Colore e forma:Solid
Peso molecolare:321.505
Ref: TM-T84459
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Prostaglandin E2-1-glyceryl ester
CAS:
- 37497-47-5
Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].
Formula:C₂₃H₃₈O₇
Colore e forma:Solid
Peso molecolare:426.55
Ref: TM-T84637