Recettore S1P
I recettori della sfingosina-1-fosfato (S1P) sono una famiglia di GPCR che si legano alla molecola segnalatrice lipidica sfingosina-1-fosfato. Questi recettori svolgono ruoli critici nel traffico delle cellule immunitarie, nello sviluppo vascolare e nel mantenimento dell'integrità delle barriere endoteliali. I modulatori dei recettori S1P sono in fase di sviluppo per il trattamento della sclerosi multipla, del cancro e delle malattie cardiovascolari grazie alla loro capacità di influenzare le risposte immunitarie e la migrazione cellulare. Presso CymitQuimica, offriamo una varietà di modulatori dei recettori S1P di alta qualità per supportare la tua ricerca in immunologia, oncologia e biologia vascolare.
Trovati 17 prodotti di "Recettore S1P"
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MP-A08
CAS:MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.Formula:C27H25N3O4S2Purezza:97.44%Colore e forma:SolidPeso molecolare:519.64Azido-FTY720
CAS:Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720, with an azido group for click chemistry reactions. FTY720 is an orally available S1P1R modulator .Formula:C19H32N4O2Colore e forma:SolidPeso molecolare:348.49SphK1&2-IN-1
CAS:<p>SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.</p>Formula:C14H14N2O3SPurezza:99.59%Colore e forma:SolidPeso molecolare:290.34Biotin Sphingosine
CAS:Cimbuterol-d9 is deuterium-labeled Cimbuterol, a 12 β(2)-adrenergic agonist.Formula:C28H52N4O4SColore e forma:SolidPeso molecolare:540.8MHP
CAS:MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.Formula:C16H23NO4Purezza:98.58%Colore e forma:SolidPeso molecolare:293.36Ref: TM-T4658
1mg35,00€2mg48,00€5mg70,00€10mg106,00€25mg217,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)78,00€Siponimod
CAS:Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.Formula:C29H35F3N2O3Purezza:99.13% - 99.8%Colore e forma:SolidPeso molecolare:516.59Opaganib
CAS:Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).Formula:C23H25ClN2OPurezza:98.86% - 99.85%Colore e forma:SolidPeso molecolare:380.91Ref: TM-T6750
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg240,00€50mg415,00€100mg615,00€1mL*10mM (DMSO)87,00€4-Deoxypyridoxine hydrochloride
CAS:4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.Formula:C8H12ClNO2Purezza:99.90%Colore e forma:White To Off White Crystalline PowderPeso molecolare:189.64SK1-IN-1
CAS:SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.Formula:C22H30N4O3Purezza:98.72%Colore e forma:SolidPeso molecolare:398.5SK1-I hydrochloride
CAS:SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.Formula:C17H28ClNO2Purezza:99.80%Colore e forma:SolidPeso molecolare:313.86N,N-Dimethylsphingosine
CAS:N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.Formula:C20H41NO2Purezza:98%Colore e forma:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderPeso molecolare:327.55SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:489.96Iso-SLR 080811
CAS:Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM).Formula:C21H32ClN5OPurezza:98.34%Colore e forma:SolidPeso molecolare:405.97S1P1 Agonist III
CAS:S1P1 Agonist III is an orally active S1P1 receptor agonist (EC₅₀ = 18 nM) with applications in inflammation, immunology, and receptor signaling studies.Formula:C21H16F3N3O3Purezza:99.08%Colore e forma:SolidPeso molecolare:415.37Amgen-23
CAS:Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.Formula:C23H25Cl2N3O2SPurezza:97.31%Colore e forma:SolidPeso molecolare:478.44K6PC-5
CAS:K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.Formula:C19H37NO4Purezza:99.9%Colore e forma:SolidPeso molecolare:343.5AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurezza:98.04% - 98.92%Colore e forma:SolidPeso molecolare:459.54
