Recettore S1P
I recettori della sfingosina-1-fosfato (S1P) sono una famiglia di GPCR che si legano alla molecola segnalatrice lipidica sfingosina-1-fosfato. Questi recettori svolgono ruoli critici nel traffico delle cellule immunitarie, nello sviluppo vascolare e nel mantenimento dell'integrità delle barriere endoteliali. I modulatori dei recettori S1P sono in fase di sviluppo per il trattamento della sclerosi multipla, del cancro e delle malattie cardiovascolari grazie alla loro capacità di influenzare le risposte immunitarie e la migrazione cellulare. Presso CymitQuimica, offriamo una varietà di modulatori dei recettori S1P di alta qualità per supportare la tua ricerca in immunologia, oncologia e biologia vascolare.
Trovati 17 prodotti di "Recettore S1P"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
MP-A08
CAS:<p>MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.</p>Formula:C27H25N3O4S2Purezza:97.44%Colore e forma:SolidPeso molecolare:519.64Azido-FTY720
CAS:<p>Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720, with an azido group for click chemistry reactions. FTY720 is an orally available S1P1R modulator .</p>Formula:C19H32N4O2Colore e forma:SolidPeso molecolare:348.49SphK1&2-IN-1
CAS:<p>SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.</p>Formula:C14H14N2O3SPurezza:99.59%Colore e forma:SolidPeso molecolare:290.34Biotin Sphingosine
CAS:<p>Cimbuterol-d9 is deuterium-labeled Cimbuterol, a 12 β(2)-adrenergic agonist.</p>Formula:C28H52N4O4SColore e forma:SolidPeso molecolare:540.8MHP
CAS:<p>MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.</p>Formula:C16H23NO4Purezza:98.58%Colore e forma:SolidPeso molecolare:293.36Siponimod
CAS:<p>Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.</p>Formula:C29H35F3N2O3Purezza:97.08% - 99.40%Colore e forma:SolidPeso molecolare:516.59Opaganib
CAS:<p>Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).</p>Formula:C23H25ClN2OPurezza:98.86% - 99.85%Colore e forma:SolidPeso molecolare:380.914-Deoxypyridoxine hydrochloride
CAS:<p>4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.</p>Formula:C8H12ClNO2Purezza:99.90%Colore e forma:White To Off White Crystalline PowderPeso molecolare:189.64SK1-I hydrochloride
CAS:<p>SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.</p>Formula:C17H28ClNO2Purezza:99.80%Colore e forma:SolidPeso molecolare:313.86N,N-Dimethylsphingosine
CAS:<p>N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.</p>Formula:C20H41NO2Purezza:98%Colore e forma:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderPeso molecolare:327.55Amgen-23
CAS:<p>Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.</p>Formula:C23H25Cl2N3O2SPurezza:97.31%Colore e forma:SolidPeso molecolare:478.44SK1-IN-1
CAS:<p>SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.</p>Formula:C22H30N4O3Purezza:98.72%Colore e forma:SolidPeso molecolare:398.5Iso-SLR 080811
CAS:<p>Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM).</p>Formula:C21H32ClN5OPurezza:98.34%Colore e forma:SolidPeso molecolare:405.97SLM6031434 HCl
CAS:<p>SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.</p>Formula:C22H31ClF3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:489.96K6PC-5
CAS:<p>K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.</p>Formula:C19H37NO4Purezza:99.9%Colore e forma:SolidPeso molecolare:343.5SAR-114137
CAS:<p>SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.</p>Formula:C25H34N4O7SPurezza:99.09% - 99.91%Colore e forma:SolidPeso molecolare:534.63AMG-369
CAS:<p>AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.</p>Formula:C26H22FN3O2SPurezza:98.04% - 98.92%Colore e forma:SolidPeso molecolare:459.54
