DHFR
La diidrofolato reduttasi (DHFR) è un enzima che svolge un ruolo cruciale nel ciclo dei folati, essenziale per la sintesi, la riparazione e la metilazione del DNA. Gli inibitori della DHFR sono ampiamente utilizzati come agenti chemioterapici nel trattamento del cancro e delle malattie autoimmuni per la loro capacità di inibire la proliferazione cellulare. Presso CymitQuimica, offriamo una varietà di inibitori della DHFR per supportare la tua ricerca in terapia del cancro, immunologia e biologia molecolare.
Trovati 32 prodotti di "DHFR"
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Sulfameter
CAS:Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.
Formula:C11H12N4O3SPurezza:99.46% - 99.90%Colore e forma:Crystalline SolidPeso molecolare:280.3P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Formula:C18H25ClN4O4Purezza:98.83%Colore e forma:SoildPeso molecolare:396.87Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formula:C20H21N5O6Purezza:98.1% - 99.92%Colore e forma:Similar To White PowderPeso molecolare:427.41Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Formula:C12H13ClN4Purezza:99.67%Colore e forma:CrystalsPeso molecolare:248.71DHFR-IN-21
DHFR-IN-21 (compound 5p) is an inhibitor of dihydrofolate reductase.Colore e forma:Odour SolidEGFR/HER2/DHFR-IN-2
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively.
Purezza:98%Colore e forma:Odour SolidCB 3705
CAS:CB 3705 is a bio-active chemical.Formula:C21H21N5O6Colore e forma:SolidPeso molecolare:439.42DHFR-IN-16
DHFR-IN-16 (compound 8d) is an inhibitor of dihydrofolate reductase (DHFR) with an IC50 of 0.199 μM, and is valuable for anti-infection research.Formula:C32H34N4O4SPeso molecolare:570.23008DHFR-IN-18
DHFR-IN-18 (compound 19D) is a DHFR inhibitor utilized in leukemia-related research.Formula:C24H22ClN7Peso molecolare:443.16252EGFR/DHFR-IN-1
EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR, with IC50 values of 0.151 µM and 0.541 µM, respectively. It induces cell cycle arrest in the G0-G1 and S phases.Formula:C24H26N4O5S2Peso molecolare:514.134464-O-Methyldopamine hydrochloride
CAS:Compound PDK0318, with CAS No. 645-33-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0318 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H13NO2Colore e forma:Slightly Beige Fluffy PowderPeso molecolare:167.2DHFR-IN-20
DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.Colore e forma:Odour SolidDHFR-IN-11
DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.Colore e forma:Odour SolidAnti-Dihydrofolate reductase Antibody (2V859)
Anti-Dihydrofolate reductase Antibody (2V859) is an antibody targeting Dihydrofolate reductase. Anti-Dihydrofolate reductase Antibody (2V859) can be used in ELISA, WB, IHC, IP.Colore e forma:Odour LiquidFanotaprim
CAS:Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Formula:C19H22N8OPurezza:98.1%Colore e forma:SolidPeso molecolare:378.43Ref: TM-T36692
1mg52,00€2mg74,00€5mg116,00€10mg178,00€25mg335,00€50mg467,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)128,00€Piritrexim isethionate
CAS:Piritrexim isethionate, a fat-soluble DHFR inhibitor, shows efficacy in metastatic urothelial cancer with a 5-day oral regimen.Formula:C19H25N5O6SColore e forma:SolidPeso molecolare:451.49WR99210 hydrochloride(47326-86-3 free base)
CAS:WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Formula:C14H19Cl4N5O2Purezza:97.77% - 99.8%Colore e forma:SolidPeso molecolare:431.14Ref: TM-T17257L
1mg62,00€5mg132,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€1mL*10mM (DMSO)157,00€WR99210
CAS:WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.Formula:C14H18Cl3N5O2Purezza:98.8%Colore e forma:SolidPeso molecolare:394.68DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Formula:C8H7BrN4Purezza:99.521% - 99.65%Colore e forma:SolidPeso molecolare:239.07Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Colore e forma:Lyophilized PowderPeso molecolare:25.6 kDa (predicted)Ref: TM-TMPH-03535
1mg2.277,00€5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€
