Sintesi del DNA/RNA
Gli inibitori della sintesi di DNA e RNA sono composti che interferiscono con i processi di replicazione e trascrizione nelle cellule, impedendo così la produzione di materiale genetico essenziale. Questi inibitori possono bersagliare vari enzimi e proteine coinvolti nella sintesi degli acidi nucleici, rendendoli strumenti preziosi per lo studio dei meccanismi di replicazione, trascrizione e traduzione. Sono inoltre utilizzati nello sviluppo di trattamenti per infezioni e cancro. Presso CymitQuimica, offriamo un ampio spettro di inibitori della sintesi di DNA/RNA per supportare la vostra ricerca in biologia molecolare, virologia e sviluppo terapeutico.
Trovati 802 prodotti di "Sintesi del DNA/RNA"
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5-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Formula:C9H11BrN2O5Purezza:99.54% - 99.87%Colore e forma:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecolare:307.1Datelliptium chloride hydrochloride
CAS:Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Formula:C23H29Cl2N3OPurezza:99.46%Colore e forma:SolidPeso molecolare:434.4PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:453.9Ref: TM-T84770
1mg84,00€5mg170,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€1mL*10mM (DMSO)195,00€5'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formula:C38H37N3O7Purezza:98.88%Colore e forma:SolidPeso molecolare:647.725-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purezza:99.89%Colore e forma:White PowderPeso molecolare:323.12'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purezza:99.35%Colore e forma:SolidPeso molecolare:325.32VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurezza:99.24% - 99.93%Colore e forma:SoildPeso molecolare:437.46Ref: TM-T85309
1mg69,00€5mg147,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€1mL*10mM (DMSO)164,00€Locked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Formula:C32H32N2O8Purezza:98%Colore e forma:SolidPeso molecolare:572.61GSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formula:C31H30F4N4O5SPurezza:99.141%Colore e forma:SoildPeso molecolare:646.65DHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Formula:C18H16N2O3S2Colore e forma:SolidPeso molecolare:372.46Metribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Formula:C8H14N4OSPurezza:99.07%Colore e forma:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecolare:214.29Tilatamig samrotecan
Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.Colore e forma:Odour SolidE-982
CAS:E-982 is derived from the reference compound.Formula:C25H31NO6SPurezza:98%Colore e forma:SolidPeso molecolare:473.582'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Formula:C9H11N5O5Purezza:98%Colore e forma:SolidPeso molecolare:269.21RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Colore e forma:SolidPeso molecolare:287.36Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purezza:99.53%Colore e forma:Off-White SolidPeso molecolare:414.68Ref: TM-T6856
1mg34,00€5mg82,00€10mg116,00€25mg227,00€50mg344,00€100mg517,00€500mg1.134,00€1mL*10mM (DMSO)92,00€3,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purezza:98.49%Colore e forma:Light Beige Crystalline PowderPeso molecolare:220.06E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Formula:C15H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:288.342-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
Formula:C5H4FN5Purezza:98.84% - 99.62%Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:153.12
