Sintesi del DNA/RNA
Gli inibitori della sintesi di DNA e RNA sono composti che interferiscono con i processi di replicazione e trascrizione nelle cellule, impedendo così la produzione di materiale genetico essenziale. Questi inibitori possono bersagliare vari enzimi e proteine coinvolti nella sintesi degli acidi nucleici, rendendoli strumenti preziosi per lo studio dei meccanismi di replicazione, trascrizione e traduzione. Sono inoltre utilizzati nello sviluppo di trattamenti per infezioni e cancro. Presso CymitQuimica, offriamo un ampio spettro di inibitori della sintesi di DNA/RNA per supportare la vostra ricerca in biologia molecolare, virologia e sviluppo terapeutico.
Trovati 798 prodotti di "Sintesi del DNA/RNA"
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Cytarabine triphosphate
CAS:Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.Formula:C9H16N3O14P3Colore e forma:SolidPeso molecolare:483.16Carboxy pyridostatin trifluoroacetate salt
Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.Formula:C37H35F3N10O9Purezza:98%Colore e forma:SolidPeso molecolare:820.735'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C38H47N3O8SiColore e forma:SolidPeso molecolare:701.892Carboxy-pyridostatin
CAS:Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.
Formula:C35H34N10O7Colore e forma:SolidPeso molecolare:706.71Nusinersen
CAS:Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.Purezza:98.62%Colore e forma:SolidChrexanthomycin C
Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.
Formula:C31H24O15Colore e forma:SolidPeso molecolare:636.51CW-2
CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).Formula:C43H42Cl2FN11O10PtColore e forma:SolidPeso molecolare:1156.21251Clofarabine-5'-triphosphate
CAS:Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.Formula:C10H14ClFN5O12P3Colore e forma:SolidPeso molecolare:543.62PAT-LM1
PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.Colore e forma:Odour LiquidGuanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Formula:C10H18N5NaO15P3Purezza:98%Colore e forma:SolidPeso molecolare:564.185EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Formula:C12H15FN5O12P3Colore e forma:SolidPeso molecolare:533.195Thailanstatin C
CAS:Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.Formula:C30H46ClNO9Colore e forma:SolidPeso molecolare:600.15Garenoxacin
CAS:Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formula:C23H20F2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:426.41HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formula:C24H27FN4O5Colore e forma:SolidPeso molecolare:470.4913-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formula:C12H19F2N6O12P3Colore e forma:SolidPeso molecolare:570.23Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purezza:98%Colore e forma:SolidPeso molecolare:848.75Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Formula:C21H25FN4O2Colore e forma:SolidPeso molecolare:384.455'-O-DMT-ibu-dC
CAS:5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.Formula:C34H37N3O7Colore e forma:SolidPeso molecolare:599.67Deoxythymidine-5'-triphosphate
CAS:Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.Formula:C10H17N2O14P3Colore e forma:SolidPeso molecolare:482.167Pyrindamycin A
CAS:Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.Formula:C26H26ClN3O8Purezza:98%Colore e forma:SolidPeso molecolare:543.95
