Sintesi del DNA/RNA
Gli inibitori della sintesi di DNA e RNA sono composti che interferiscono con i processi di replicazione e trascrizione nelle cellule, impedendo così la produzione di materiale genetico essenziale. Questi inibitori possono bersagliare vari enzimi e proteine coinvolti nella sintesi degli acidi nucleici, rendendoli strumenti preziosi per lo studio dei meccanismi di replicazione, trascrizione e traduzione. Sono inoltre utilizzati nello sviluppo di trattamenti per infezioni e cancro. Presso CymitQuimica, offriamo un ampio spettro di inibitori della sintesi di DNA/RNA per supportare la vostra ricerca in biologia molecolare, virologia e sviluppo terapeutico.
Trovati 798 prodotti di "Sintesi del DNA/RNA"
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5'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C38H47N3O8SiColore e forma:SolidPeso molecolare:701.892EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Formula:C12H15FN5O12P3Colore e forma:SolidPeso molecolare:533.195MRK-952
MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.Formula:C20H20ClF3N6Colore e forma:SolidPeso molecolare:436.861Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purezza:98%Colore e forma:SolidPeso molecolare:848.75Xanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.
Formula:C10H15N4O15P3Colore e forma:SolidPeso molecolare:524.164Guanosine triphosphate
CAS:Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Formula:C10H16N5O14P3Colore e forma:SolidPeso molecolare:523.1816,16-dimethyl Prostaglandin A1
CAS:16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.Formula:C22H36O4Colore e forma:SolidPeso molecolare:364.5265-BrdUTP sodium salt
CAS:5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.Formula:C9H10BrN2Na4O14P3Purezza:98%Colore e forma:SolidPeso molecolare:634.972'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.Formula:C10H14N5Na2O8PColore e forma:SolidPeso molecolare:409.202Mulnitorsen
CAS:Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].Formula:C172H217N74O82P17S17Colore e forma:SolidPeso molecolare:5704.66Garenoxacin
CAS:Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formula:C23H20F2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:426.41(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Formula:C25H34O10Colore e forma:SolidPeso molecolare:494.537CW-2
CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).Formula:C43H42Cl2FN11O10PtColore e forma:SolidPeso molecolare:1156.21251R-1479
CAS:R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.Formula:C9H12N6O5Purezza:98.11% - 99.95%Colore e forma:SolidPeso molecolare:284.23Ref: TM-TQ0162
1mg104,00€5mg258,00€10mg358,00€25mg595,00€50mg842,00€100mg1.134,00€200mg1.521,00€1mL*10mM (DMSO)318,00€Bz-rC Phosphoramidite
CAS:Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.
Formula:C52H66N5O9PSiColore e forma:SolidPeso molecolare:964.185RNA polymerase II-IN-2
RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.Formula:C41H58N10O12SColore e forma:SolidPeso molecolare:915.025-Methylcytidine 5′-triphosphate
CAS:5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innateFormula:C10H18N3O14P3Colore e forma:SolidPeso molecolare:497.18Carbazole
CAS:Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.
Formula:C12H9NPurezza:99.82%Colore e forma:SolidPeso molecolare:167.211KWR137
KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.Formula:C33H31ClF3N9O4Colore e forma:SolidPeso molecolare:710.1055'-O-DMT-Bz-rC
CAS:5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C37H35N3O8Colore e forma:SolidPeso molecolare:649.69
