Antibiotico

<p>Antibioticadjuvant 2 (compound 5q) is a potent antibiotic adjuvant that enhances the efficacy of polymyxins and exhibits low toxicity in mammals. The minimum resensitization concentration of Antibioticadjuvant 2 for Escherichia coli AR-0493 is 0.125 μg/mL.</p>

Malolactomycin C (compound 1) is a macrocyclic lactone antifungal antibiotic isolated from the Streptomyces strain KP-3144. It effectively inhibits Botrytis cinerea (gray mold), thereby controlling various plant diseases, including gray mold infections.

TAN-420C is an antibiotic isolated from Streptomyces hygroscopicus with antitumour activity.

Bacitracin (Ziba-RX), a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.

Altromycin C is a new pluramycin-like antibiotic.

10,11-Dehydrocurvularin: antibiotic, activates heat shock response, blocks TGF-β, anti-cancer.

Dehydrogriseofulvin is a natural product that can be used as a reference standard. The CAS number of Dehydrogriseofulvin is 3573-90-8.

Septacidin represents a group of l-eptopyranoses including nucleoside antibiotics with antitumor, antifungal, and pain-relief activities.

Cefuzonam sodium: second-gen cephalosporin, effective against Staph aureus where third-gen fails.

AB023b is an antibiotic with antifungal properties.

<p>Lincosamine is a lincosamide antibiotic produced by Streptomyces lincolnensis.</p>

BU-2313 A is a new antibiotic complex. It also active against anaerobes.

Sordarin, from S. araneosa, inhibits fungal EF-2 protein synthesis; effective against C. albicans with varying potency on other species.

Mycinamicin I is a macrolide antibiotic.

Elaiophylin exhibits anti-Plasmodium falciparum and anti-Trypanosoma brucei activity; IC50: 0.36 μM & 0.45 μM, respectively.

Dactylarin: cytotoxic antibiotic from Dactylaria lutea, interacts with thiols, inhibits glycolytic enzymes.

Laidlomycin phenylcarbamate is a semi-synthetic polyether antibiotic.

Ceftiofur hydrochloride (U-67279A) is a stable, broad-spectrum 3rd-gen cephalosporin with antibacterial properties.

Kijimicin is a polyether antibiotic and human immunodeficiency virus inhibitor in acutely and chronically infected cells.

5H-Pyrido[3,2-b]indole inhibits Plasmodium falciparum and Trypanosoma cruzi, exhibits cytotoxicity toward L6 cells

Levorin A0 is a Levorin component.

AB023a is an antibiotic with antifungal properties.

A-39183A, from Streptomyces NRRL 12049, targets penicillin-resistant S. aureus & S. faecalis (MICs 32 μg/ml), plus other anaerobes (MICs 16-128 μg/ml).

Calphostin C is a protein kinase C inhibitor.

<p>Protorubradirin is an antibiotic that can be isolated from the non-pigmented Streptomyces achromogenes var. rubradiris alongside Rubradirin. It exhibits inhibitory activity against HIV reverse transcriptase. In vitro studies show that Protorubradirin also inhibits strains of Staphylococcus aureus and Streptococcus. In infected mice, subcutaneous administration of Protorubradirin demonstrates in vivo efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may significantly reduce its activity compared to Rubradirin, possibly due to its C-nitroso sugar decomposing more rapidly in acidic gastric conditions.</p>

Bacilysin possesses antibactirial activity.

<p>Gramicidin (Gramicidine) is an antimicrobial peptide. Gramicidin is effective against Gram-positive bacteria. Cost-effective and quality-assured.</p>

Cladospirone bisepoxide, a fungal metabolite, is a selective antibiotic that also hinders L. sativum germination.

Posizolid(AZD-5847,AZD-2563) is an oxazolidinone antibiotic under investigation by AstraZeneca for the treatment of bacterial infections.

Saccharocarcin B was isolated from the fermentation broth of the actinomycete Saccharothrix aerocolongenes subsp.antibiotica SCC1886.

Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.

Isosulfazecin is a beta-lactam antibiotic.

<p>Anguinomycin A, an antibiotic from Streptomyces, is like leptomycin B, kills mouse leukemia cells, and fights lung cancer in mice.</p>

Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)

Leucinostatin B is a peptide antibiotic from Paecilomyces lilacinus A-267.

Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.

Bleomycin B4 (Phleomycin F), an antibiotic with antitumor properties, is utilized in cancer research [1] [2] [3].

Distamycin A (NSC-82150), oligopeptide antibiotic, binds A/T rich DNA, affects cleavage sites, enhances apoptosis.

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

<p>Lincomycin hydrochloride (U10149A) is a lincosamide antibiotic identified in S.lincolnensis with activity against gram-positive cocci and anaerobic bacteria.</p>

Bibrocathol is a well-established antiseptic drug used for the treatment of acute eyelid diseases like blepharitis.

Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.

<p>Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, effectively inhibits chitin synthetase.</p>

Mandipropamid specifically induces complex formation between PYR1 and abscisic acid-insensitive hexameric mutants.

<p>Eravacycline HCl (TP-434 HCl) is potent antibiotic with broad-spectrum antibacterial activity.</p>

Amphotericin A is a potent antifungal antibiotic [1] .

Peplomycin: a Bleomycin analog with potent antitumor properties & reduced lung toxicity. Induces apoptosis in SSCKN cells & rat pulmonary fibrosis.

Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.

Carbomycin B, a precursor in making Carbomycin, is a macrolite antibiotic from Stroptomyces halstedii, akin to Leucomycin and Erythromycin.

<p>Ikarugamycin, an antibiotic, is an inhibitor of clathrin-mediated endocytosis (CME).</p>