Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 508 prodotti di "Proteasi HIV"
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HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurezza:98%Colore e forma:SolidPeso molecolare:1285.683′-Deoxy Thymidine
CAS:3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC50 = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.Formula:C10H14N2O4Purezza:99.89%Colore e forma:SolidPeso molecolare:226.23HIV-1 inhibitor-10
CAS:HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.Formula:C39H54O6Colore e forma:SolidPeso molecolare:618.84BILR-355
CAS:BILR-355 is a reverse transcriptase inhibitor.Formula:C25H23N5O3Purezza:98%Colore e forma:SolidPeso molecolare:441.48PYR01
CAS:PYR01 is a potent nonnucleoside reverse transcriptase inhibitor of HIV-1 and concurrently acts as a targeted activator to eliminate cells expressing HIV-1 [1].Formula:C21H13F7N4O3Colore e forma:SolidPeso molecolare:502.34Ro 31-8588
CAS:Talviraline (HBY 097) inhibits HIV-1 replication and reduces cell death in various cells and immune cells.Formula:C33H56N4O5Colore e forma:SolidPeso molecolare:588.827-Deaza-2',3'-dideoxyguanosine
CAS:7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].Formula:C11H14N4O3Colore e forma:SolidPeso molecolare:250.25DMP 323
CAS:DMP 323 is a potent inhibitor of HIV-1 protease.Formula:C35H38N2O5Purezza:98%Colore e forma:SolidPeso molecolare:566.6912-Bromododecanoic Acid
CAS:12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV replication in CEM-SS T cells with an EC50 value of 38 µM.Formula:C12H23BrO2Colore e forma:SolidPeso molecolare:279.218WRNA10
CAS:WRNA10 is a potent binding agent for HIV-1TAR RNA (IC50: 10 μM, CC50: 40 μM).Formula:C25H32N4O4Colore e forma:SolidPeso molecolare:452.55Murabutide
CAS:Murabutide, a safe synthetic immunomodulator, diminishes the expression of CD4 and CCR5 receptors and promotes the secretion of high levels of beta-chemokines,Formula:C23H40N4O11Colore e forma:SolidPeso molecolare:548.58A 77003
CAS:A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.Formula:C44H58N8O6Colore e forma:SolidPeso molecolare:794.98HIV-1 inhibitor-3
CAS:HIV-1 inhibitor-3 is an HIV infection inhibitor.Formula:C9H10F2N2O5Purezza:98%Colore e forma:SolidPeso molecolare:264.18XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Colore e forma:SolidPeso molecolare:446.45Bavtavirine
CAS:<p>Bavtavirine is a non-nucleoside reverse HIV-1 transcriptase inhibitor (NNRTIs),inhibits HIV replication by preventing the transcription of viral RNA into DNA.</p>Formula:C26H20N6Purezza:97.2%Colore e forma:SolidPeso molecolare:416.48PDDC inhibitor
CAS:PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.Formula:C27H29N5O4Purezza:96.09% - 99.39%Colore e forma:SolidPeso molecolare:487.55HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formula:C27H30N6O4SPurezza:98.05% - 99.39%Colore e forma:SoildPeso molecolare:534.63Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:229.26NNRT-IN-2
CAS:NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formula:C19H14F3N5O3Peso molecolare:417.34HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formula:C27H31FN2O6SColore e forma:SolidPeso molecolare:530.61
