Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 506 prodotti di "Proteasi HIV"
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NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formula:C32H31N9O3SColore e forma:SolidPeso molecolare:621.71Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidRef: TM-L1100
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaSDZ 283-910
CAS:SDZ 283-910 is used as a statine-derived inhibitor.Formula:C46H59N5O9Purezza:98%Colore e forma:SolidPeso molecolare:826.004Schineolignin B
Schineolignin B is a useful organic compound for research related to life sciences and the catalog number is T126011.Formula:C22H30O5Colore e forma:SolidPeso molecolare:374.477Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formula:C21H17F3N3NaO5Purezza:99.97%Colore e forma:SolidPeso molecolare:471.364-Deoxy-4α-phorbol
CAS:4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E.Formula:C20H28O5Colore e forma:SolidPeso molecolare:348.43CI-39
CAS:CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.Formula:C19H18N2O4Colore e forma:SolidPeso molecolare:338.36(2S,5S)-Censavudine
(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.Formula:C12H12N2O4Colore e forma:SolidPeso molecolare:248.23HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour SolidJE-2178
CAS:JE-2178 is compound with high bioavailability .Formula:C35H51N5O6SColore e forma:SolidPeso molecolare:669.87Tenofovir-C3-O-C15-CF3 ammonium
CAS:Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.Formula:C28H52F3N6O5PColore e forma:SolidPeso molecolare:640.73HIV-IN-2
CAS:HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].Formula:C34H27ClF7N9O3SColore e forma:SolidPeso molecolare:810.14Decanoyl-RVKR-CMK
CAS:Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.Formula:C34H66ClN11O5Purezza:98%Colore e forma:SolidPeso molecolare:744.42Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFormula:C20H28O3Colore e forma:SolidPeso molecolare:316.43CTP518
CAS:CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.Formula:C38H52N6O7Purezza:98%Colore e forma:SolidPeso molecolare:719.95Emtricitabine S-oxide
CAS:Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.Formula:C8H10FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:263.25Pol (476-484), HIV-1 RT Epitope
CAS:Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (Formula:C46H78N12O12Colore e forma:SolidPeso molecolare:991.18Dihydroobionin B
Dihydroobionin B exhibits potent (please insert the rest of the sentence for revision).Formula:C21H26O5Colore e forma:SolidPeso molecolare:358.43(+)-Carbovir triphosphate
CAS:(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.Formula:C11H16N5O11P3Colore e forma:SolidPeso molecolare:487.19Decanoyl-RVKR-CMK TFA
CAS:<p>Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.</p>Formula:C36H67ClF3N11O7Colore e forma:SolidPeso molecolare:858.45Lopinavir Metabolite M-1
CAS:Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.Formula:C37H46N4O6Colore e forma:SolidPeso molecolare:642.78Hypoglaunine D
CAS:Hypoglaunine D, an anti-HIV analogue of Triptonine B, inhibits HIV in H9 cells with an EC50 of 22 μg/ml.Formula:C41H47NO19Colore e forma:SolidPeso molecolare:857.81GLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purezza:98%Colore e forma:SolidPeso molecolare:2300.89HIV-1 protease-IN-4
HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.Formula:C48H69N7O11Colore e forma:SolidPeso molecolare:920.1Carbovir triphosphate
CAS:Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Formula:C11H16N5O11P3Colore e forma:SolidPeso molecolare:487.19TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formula:C65H124N34O15Purezza:98%Colore e forma:SolidPeso molecolare:1621.91Kadsuralignan A
CAS:Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with anFormula:C22H26O7Colore e forma:SolidPeso molecolare:402.44QYL-685
CAS:QYL-685 is a methylenecyclopropane nucleoside analog.Formula:C20H24N7O5PColore e forma:SolidPeso molecolare:473.42HIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Formula:C28H28FN5O3SColore e forma:SolidPeso molecolare:533.62RPR103611
CAS:RPR103611, a betulinic acid derivative, inhibits HIV-1; IC50s: CCR5 (YU2) 80, CXCR4 (NL4-3) 0.27, dual-tropic (89.6) 0.17.Formula:C46H78N2O6Colore e forma:SolidPeso molecolare:755.12Scirpusin A
CAS:Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.Formula:C28H22O7Colore e forma:SolidPeso molecolare:470.47PROTAC Vif degrader-1
PROTACVif degrader-1 (Compound L15) is a Vif-targeted PROTAC degrader exhibiting anti-HIV-1 virucidal activity, with an EC50 of 33.35 μM against HIV-1IIIB.Colore e forma:Odour SolidDelavirdine
CAS:<p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>Formula:C22H28N6O3SColore e forma:SolidPeso molecolare:456.56MB-66
MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.Colore e forma:Odour LiquidHIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Colore e forma:Odour SolidGlobotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formula:C60H113NO18Colore e forma:SolidPeso molecolare:1136.553ICeD-2
ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.Formula:C20H29N3OColore e forma:SolidPeso molecolare:327.4612-Oxocalanolide A
12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.Formula:C22H24O5Colore e forma:SolidPeso molecolare:368.429Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formula:C67H124N34O14SPurezza:98%Colore e forma:SolidPeso molecolare:1661.99Salvianan A
CAS:<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Formula:C20H17NO2Colore e forma:SolidPeso molecolare:303.35HIV gag peptide (197-205)
CAS:HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFormula:C45H81N11O14S2Purezza:98%Colore e forma:SolidPeso molecolare:1064.32HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Formula:C42H36ClF10N7O5S2Colore e forma:SolidPeso molecolare:1008.35Kuguacin N
Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.Formula:C30H46O4Colore e forma:SolidPeso molecolare:470.694HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purezza:98%Colore e forma:SolidPeso molecolare:396.56Indoline
CAS:Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H9NColore e forma:Clear To Yellow LiquidPeso molecolare:119.16HIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Formula:C32H44N2O8SColore e forma:SolidPeso molecolare:616.77Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Formula:C37H56F3N9O18Purezza:98%Colore e forma:SolidPeso molecolare:971.89HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formula:C44H72N10O15Purezza:98%Colore e forma:SolidPeso molecolare:981.1Epicoccone B
CAS:Epicoccone B from C. globosum has DPPH scavenging (IC50=10.8μM) and α-glucosidase inhibition (IC50=27.3μM), also anti-HIV.Formula:C9H8O5Colore e forma:SolidPeso molecolare:196.16
