Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 508 prodotti di "Proteasi HIV"
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SPD-756
CAS:SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C12H16N6O3Purezza:98%Colore e forma:SolidPeso molecolare:292.29Scirpusin A
CAS:Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.Formula:C28H22O7Colore e forma:SolidPeso molecolare:470.47HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormula:C26H24N6O2Colore e forma:SolidPeso molecolare:452.51Salvianan A
CAS:1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].Formula:C20H17NO2Colore e forma:SolidPeso molecolare:303.35Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidRef: TM-L1100
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaDecanoyl-RVKR-CMK TFA
CAS:<p>Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.</p>Formula:C36H67ClF3N11O7Colore e forma:SolidPeso molecolare:858.45Epicoccone B
CAS:Epicoccone B from C. globosum has DPPH scavenging (IC50=10.8μM) and α-glucosidase inhibition (IC50=27.3μM), also anti-HIV.Formula:C9H8O5Colore e forma:SolidPeso molecolare:196.16Dihydroobionin B
Dihydroobionin B exhibits potent (please insert the rest of the sentence for revision).Formula:C21H26O5Colore e forma:SolidPeso molecolare:358.43mC46 peptide
mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor that effectively impedes the replication and entry of HIV-1. Additionally, mC46 peptide can inhibit CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, as well as SIV and SHIV.Formula:C263H381N67O82SColore e forma:SolidPeso molecolare:5825.3Kadsuralignan A
CAS:Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with anFormula:C22H26O7Colore e forma:SolidPeso molecolare:402.44(-)-Rabdosiin
CAS:(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].Formula:C36H30O16Colore e forma:SolidPeso molecolare:718.61PNU-142721
CAS:PNU-142721, reverse transcriptase inhibitor, is used to treat human immunodeficiency virus (HIV) infection.Formula:C13H11ClN4OSColore e forma:SolidPeso molecolare:306.77Pol (476-484), HIV-1 RT Epitope
CAS:Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (Formula:C46H78N12O12Colore e forma:SolidPeso molecolare:991.18HIV-1 inhibitor-78
HIV-1inhibitor-78 (compound 15f) is a potent and broad-spectrum non-nucleoside reverse transcriptase inhibitor, with an EC50 value of 3 nM against wild-type HIV-1. It is useful for research on HIV infections.Formula:C32H34N6O4SColore e forma:SolidPeso molecolare:598.72N36Mut(e,g)
N36Mut(e,g) is an HIV fusion peptide inhibitor targeting gp41. It functions by disrupting the formation of the homotrimeric coiled coil of the N-terminal helix in the pre-hairpin intermediate, leading to the creation of a heterotrimer.Formula:C189H317N55O56Colore e forma:SolidPeso molecolare:4255.87PROTAC Vif degrader-1
PROTACVif degrader-1 (Compound L15) is a Vif-targeted PROTAC degrader exhibiting anti-HIV-1 virucidal activity, with an EC50 of 33.35 μM against HIV-1IIIB.Colore e forma:Odour SolidEmtricitabine S-oxide
CAS:Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.Formula:C8H10FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:263.25Indoline
CAS:Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H9NColore e forma:Clear To Yellow LiquidPeso molecolare:119.16HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour Solid[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)
CAS:[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].Formula:C76H108N14O26SColore e forma:SolidPeso molecolare:1665.81NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1407.17VIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Formula:C109H158N22O25S2Purezza:98%Colore e forma:SolidPeso molecolare:2240.7GP120, HIV-1 MN
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2].Formula:C135H221N45O33Colore e forma:SolidPeso molecolare:3002.5HIV Protease Substrate 1 TFA
HIV Protease Substrate 1 TFA, a fluorogenic substrate for HIV protease, facilitates the investigation of the enzyme's activity [1].Formula:C94H134F3N27O25SColore e forma:SolidPeso molecolare:2131.29Peptide T
CAS:Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.Formula:C35H55N9O16Purezza:98%Colore e forma:SolidPeso molecolare:857.86BNM-III-170
CAS:<p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>Formula:C25H26ClF7N6O6Colore e forma:SolidPeso molecolare:674.96RPR103611
CAS:RPR103611, a betulinic acid derivative, inhibits HIV-1; IC50s: CCR5 (YU2) 80, CXCR4 (NL4-3) 0.27, dual-tropic (89.6) 0.17.Formula:C46H78N2O6Colore e forma:SolidPeso molecolare:755.12CI-39
CAS:CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 >30 µM.Formula:C19H18N2O4Colore e forma:SolidPeso molecolare:338.36AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Colore e forma:SolidPeso molecolare:1328.2HIV-IN-2
CAS:HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].Formula:C34H27ClF7N9O3SColore e forma:SolidPeso molecolare:810.14HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Colore e forma:Odour SolidGlobotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formula:C60H113NO18Colore e forma:SolidPeso molecolare:1136.553Tenofovir-C3-O-C15-CF3 ammonium
CAS:Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.Formula:C28H52F3N6O5PColore e forma:SolidPeso molecolare:640.73JE-2178
CAS:JE-2178 is compound with high bioavailability .Formula:C35H51N5O6SColore e forma:SolidPeso molecolare:669.874-Deoxy-4α-phorbol
CAS:4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E.Formula:C20H28O5Colore e forma:SolidPeso molecolare:348.43L 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formula:C38H47N5O5Colore e forma:SolidPeso molecolare:653.81HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purezza:98%Colore e forma:SolidPeso molecolare:396.56HIV-1 inhibitor-80
<p>HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.</p>Formula:C26H19N7OColore e forma:SolidPeso molecolare:445.475Elvucitabine
CAS:Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.Formula:C9H10FN3O3Colore e forma:SolidPeso molecolare:227.19Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS:Tenofovir-C3-O-C12 has a longer half-life, potent anti-HIV effects, and better pharmacokinetics than tenofovir.Formula:C29H55N6O5PSiColore e forma:SolidPeso molecolare:626.855Enfuvirtide
CAS:Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.Formula:C204H301N51O64Purezza:98%Colore e forma:White To Off-White Amorphous SolidPeso molecolare:4491.945HIV protease-IN-1
CAS:HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1].Formula:C39H40ClF7N10O7Colore e forma:SolidPeso molecolare:929.24Aureothin
CAS:Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Formula:C22H23NO6Colore e forma:SolidPeso molecolare:397.42TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formula:C65H124N34O15Purezza:98%Colore e forma:SolidPeso molecolare:1621.91GLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purezza:98%Colore e forma:SolidPeso molecolare:2300.89KRL74
CAS:KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 μM and a Kd of 11.9 μM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 μM in virus-like particle (VLP) budding assays.Formula:C50H61ClN10O9Colore e forma:SolidPeso molecolare:981.53MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formula:C126H201N35O33SPurezza:98%Colore e forma:SolidPeso molecolare:2766.22HIV-1 protease-IN-4
HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.Formula:C48H69N7O11Colore e forma:SolidPeso molecolare:920.1(+)-Carbovir triphosphate
CAS:(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.Formula:C11H16N5O11P3Colore e forma:SolidPeso molecolare:487.19Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFormula:C20H28O3Colore e forma:SolidPeso molecolare:316.43
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