Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 502 prodotti di "Proteasi HIV"
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Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColore e forma:SolidPeso molecolare:349.858BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColore e forma:SolidPeso molecolare:570.619A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purezza:98%Colore e forma:SolidPeso molecolare:794.98GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColore e forma:SolidPeso molecolare:659.24L 702007
CAS:L 702007 is an inhibitor of HIV-1 reverse transcriptase.Formula:C18H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:315.41Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Colore e forma:SolidPeso molecolare:157.21NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Formula:C20H25ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:436.96Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:229.26HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.Formula:C21H32ClN7O3Colore e forma:SolidPeso molecolare:465.98ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Colore e forma:Solid4'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purezza:98%Colore e forma:SolidPeso molecolare:275.26(S)-Batylalcohol
CAS:<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>Formula:C21H44O3Colore e forma:SolidPeso molecolare:344.572Desthiazolylmethyl ritonavir
CAS:Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.Formula:C33H43N5O4SColore e forma:SolidPeso molecolare:605.791HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formula:C16H15F2N3OSColore e forma:SolidPeso molecolare:335.37HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Formula:C24H24F2N2O2SColore e forma:SolidPeso molecolare:442.52Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColore e forma:SolidPeso molecolare:727.07HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.Formula:C25H18N6O2Colore e forma:SolidPeso molecolare:434.45HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Formula:C27H31N3O6SColore e forma:SolidPeso molecolare:525.62HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formula:C27H31FN2O6SColore e forma:SolidPeso molecolare:530.61HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.Formula:C29H32N6O4SColore e forma:SolidPeso molecolare:560.67
