Antibatterico

<p>Dapdiamide A is an antibiotic identified in the Pantoea agglomerans CU0119 strain, displaying antibacterial activity and offering potential for research in anti-infective treatments.</p>

<p>Kyotorphin is a Morphine-like dipeptide.</p>

<p>Demethyl linezolid, an impurity in linezolid (WO199500721A1, ex. 9), has antimicrobial effects on human and veterinary pathogens.</p>

<p>K 41 is a polycyclic polyether antibiotic from Streptomyces hygroscopicus.</p>

<p>Aurein 2.4, an antibiotic antimicrobial peptide, exhibits activity against Gram-positive bacteria [1] [2].</p>

<p>Tur1A, an antimicrobial peptide sourced from the bottlenose dolphin (Tursiops truncates), impedes bacterial protein synthesis.</p>

<p>Compound PDK0270, with CAS No. 551-16-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0270 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>HBA(111-142), a C-terminal 32-mer fragment of alpha-hemoglobin, exhibits antibacterial activity against the ESKAPE panel of pathogens, forms amyloid fibrils,</p>

<p>Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics from several Streptomyces that directly inhibit bacterial PGTs.</p>

<p>Amythiamicin D is a thiopeptide antibiotic that effectively inhibits the growth of various Gram-positive bacteria, but it is ineffective against Gram-negative bacteria such as Escherichia coli.</p>

<p>Maximin H3, an antimicrobial peptide from Chinese red belly toad Bombina maxima skin secretions, exhibits antimicrobial properties against Escherichia coli</p>

<p>elomycin is a cyclic depsipeptide antibiotic with activity against Gram-positive bacteria.</p>

<p>Rifamycin: Natural antibiotic; blocks prokaryotic RNA synthesis by halting RNA-polymerase.</p>

<p>Ambazone hydrate has anti-cancer activity.</p>

<p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>

<p>cis-11-Methyl-2-dodecenoic acid: a QS signal, aids microbial communication, regulates virulence, biofilm in pathogens.</p>

<p>Zelkovamycin, a cyclic peptide antibiotic, blocks X. oryzae, P. oryzae, S. aureus, A. laidlawii growth at 0.01-300 μg/ml concentration.</p>

<p>Viomycin: tuberactinomycin antibiotic, halts prokaryotic protein synthesis and group I intron splicing, arrests bacterial ribosomes.</p>

<p>Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria.</p>

<p>Sitafloxacin (DU6859a) is a potent fluoroquinolone, effective against a wide spectrum of bacteria and used for respiratory and urinary infections.</p>

<p>Atrovenetin is an antibiotic found in Penicillium species (antibiotic). It exhibits inhibitory activity against Bacillus subtilis and Staphylococcus aureus. Atrovenetin is also a potent antioxidant.</p>

<p>Saccharocarcin A, an antibiotic from S. aerocolonigenes, combats various bacteria and inhibits C. trachomatis at 0.5 μg/ml, non-toxic to McCoy cells.</p>

<p>DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.</p>

<p>Antimicrobial agent-26 is a powerful antimicrobial that has demonstrated the ability to counteract antibiotic resistance in vitro [1].</p>

<p>Emeguisin A, a depsidone from E. unguis, fights S. aureus, MRSA, C. neoformans (MIC 0.5 μg/ml), and P. falciparum (IC50 2.2 μM).</p>

<p>'10'-Desmethoxystreptonigrin antibiotic derived from streptonigrin combats various bacteria and cancer cells, and inhibits p21ras farnesylation (IC50 = 21 nM).</p>

<p>Sisomicin is a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. It is highly active against staphylococci.</p>

<p>Cafamycin is a bioactive chemical.</p>

<p>Avilamycin A: antibiotic, combats C. perfringens and B. hyodysenteriae, lowers mortality in poultry.</p>

<p>Penicillin V: orally active antibiotic against Streptococci, C. difficile, and S. aureus; treats otitis, sinusitis, pharyngitis, tonsillitis.</p>

<p>Brevianamide M (compound 4), a metabolite of the endophytic fungus Aspergillus versicolor isolated from the marine brown alga Sargassum, exhibits antimicrobial</p>

<p>Cefalexin lysine is a derivative of Cefalexin which is an antibiotic.</p>

<p>Bombinin H4 is an antimicrobial peptide originating from the skin of the moth species Bombina variegata.</p>

<p>Antibacterial agent 59 (example 24) is a antibacterial agent.</p>

<p>Antibacterial agent 55 (example 21) is a antibacterial agent.</p>

<p>Prodigiosin hydrochloride is a bioactive red pigment from bacteria with antibacterial, antifungal, anticancer properties, and inhibits Wnt/β-catenin.</p>

<p>Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.</p>

<p>Kipukasin D is a naturally derived nucleoside with antibacterial properties, isolated from Aspergillus versicolor.</p>

<p>Nybomycin, a fungal metabolite from Streptomyces sp. A717, has antibacterial properties; effective against various bacteria including M. tuberculosis.</p>

<p>Tryptophanase, a bacterial enzyme, catalyzes the degradation of tryptophan into indole, pyruvate, and ammonia [1].</p>

<p>Isodihydroauroglaucin is a useful organic compound for research related to life sciences. The catalog number is T124274 and the CAS number is 74886-31-0.</p>

<p>Efflux pump-IN-4 inhibits AcrB, enhancing antibiotic potency without harming bacterial membranes or nematodes.</p>

<p>β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity.</p>

<p>Dicresulene diammonium is an impurity found in Policresulen, which is an organic acid possessing hemostatic, antimicrobial, and antiviral properties[1][2].</p>

<p>Psoracorylifol B is a natural product that can be used as a reference standard.</p>

<p>Neamine: antibiotic, anti-angiogenic, battles bacteria, cancer, protects nerves.</p>

<p>Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and</p>

<p>Pristinamycin, from Streptomyces pristinaespiralis, is a streptogramin antibiotic targeting Gram-positive and resistant bacteria like MRSA.</p>

<p>Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].</p>

<p>Kapurimycin A3 is an antitumor antibiotics.</p>

<p>Cefoperazone dihydrate, a semi-synthetic cephalosporin, exhibits a wide range of antibacterial properties.</p>

<p>Psoracorylifol C is a useful organic compound for research related to life sciences and the catalog number is T124015.</p>

<p>Halocyamine B, isolated from Halocynthia roretzi, is an antibiotic peptide.</p>

<p>Lugdunin is an antibiotic peptide that disrupts membrane potential in bacteria, demonstrating activity against Gram-positive species including S.</p>

<p>Bacteria use quorum sensing with autoinducers like AHLs to regulate gene expression and behaviors such as biofilm formation.</p>

<p>Cefalonium hydrate: a β-lactam antibiotic for bovine mastitis from Gram-positive bacteria, especially staphylococci, with marked effectiveness.</p>

<p>SPR741, a cationic peptide from polymyxin B, is being developed to treat serious Gram-negative infections.</p>

<p>2-Phenoxyphenol has antibacterial against Staphylococcus aureus, Staphylococcus aureus, Escherichia coli, Burkholderia pseudomallei, etc.</p>

<p>1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.</p>

<p>JH-LPH-28, a sulfonyl piperazine, inhibits LpxH with strong antibiotic activity, MIC of 0.83 μg/mL.</p>

<p>Dienone B is a cytotoxic secondary metabolite from tyrosine as isolated from the sponges Verongia aerophoba &amp;amp; Aplysina aerophoba.</p>

<p>Quorum sensing-IN-10 (10p) is an antimicrobial adjuvant that significantly inhibits the virulence, biofilm formation, and motility of Pseudomonas aeruginosa, while exhibiting low toxicity. It is applicable for research related to drug-resistant Pseudomonas aeruginosa infections.</p>

<p>Cephabacin M4 is a new cephem antibiotic isolated from bacterial.</p>

<p>NR-NO2 is a prospective therapeutic agent with targeted delivery and image-guided capability for use in antitumor studies, also demonstrating antibacterial</p>

<p>BAL30072: Antibiotic effective against MDR Acinetobacter (4 μg/mL) and P. aeruginosa (8 μg/mL); a monocyclic beta-lactam.</p>

<p>Angustifoline HCl, from Lupinus angustifolius, has antimicrobial effects on S. aureus, B. subtilis, E. coli, P. aeruginosa, B. thuringiensis.</p>

<p>Cephaloridine hydrate, a broad-spectrum antibacterial antibiotic, exhibits dose-related nephrotoxicity [1] [2].</p>

<p>Antibacterial agent 60 is a potent compound that effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, an antibacterial agent.</p>

<p>Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria.</p>

<p>Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.</p>

<p>Mtb-IN-3 (compound 10c), a selective and potent Mycobacterium tuberculosis (Mtb) inhibitor, exhibits strong antimycobacterial activity in vitro without inducing</p>

<p>Setomimycin is an antibiotic against Gram positive bacteria, including mycobacteria.</p>

<p>Trinactin is a nonactin homolog that has Immunosuppressive effects.</p>

<p>N-Hydroxypipecolic acid potassium is a metabolite of plant and a systemic acquired resistance (SAR) regulator.</p>

<p>Kapurimycin A1 is an antitumor antibiotic produced by Streptomyces.</p>

<p>Cloxacillin Sodium: chlorinated Oxacillin derivative, semi-synthetic, treats beta-lactamase staph infections.</p>

<p>Ecteinascidin-Analog-1, a tetrahydroisoquinoline, is key for synthesizing ecteinascidin analogs with antitumor and antimicrobial properties.</p>

<p>Maximin H1, an antimicrobial peptide sourced from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits efficacy against several</p>

<p>Anthracen-1-amine exhibits inhibitory activity against Escherichia coli.</p>

<p>Plantaricin A, an antimicrobial peptide extracted from Lactobacillus plantarum, exhibits efficacy against bacteria [1].</p>

<p>Collinin, a coumarin in Z. schinifolium, combats M. tuberculosis and inhibits NO production, platelet aggregation, and tumor growth in mice.</p>

<p>S-6123: Oxazolidinone antimicrobial that blocks ribosomal protein synthesis, sparing DNA/RNA.</p>

<p>Hc-CATH (Sea snake cathelicidin) is a broad-spectrum antibacterial peptide effective against Shigella dysenteriae and Klebsiella pneumoniae, with MIC values ranging from 0.16 to 20.67 mM. Additionally, Hc-CATH demonstrates anti-inflammatory efficacy.</p>

<p>2-Benzylaniline is a potential Cytochrome P450 2B6 inhibitor with an IC50 value of 4.36 μM.</p>

<p>AA45 boosts Ceftazidime's efficacy by lowering its MIC value, showcasing strong antibacterial properties.</p>

<p>Altromycin F is a new pluramycin-like antibiotic.</p>

<p>Almurtide: Muramyl dipeptide derivative with anti-inflammatory, anti-tumor properties, protects mice from Pseudomonas and Candida infections.</p>

<p>Urechistachykinin I (Uru-TK I) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.</p>

<p>Saptomycin D, an antibiotic (antibiotic) isolated from the Streptomyces sp. HP530 strain, exhibits potent antitumor activity. It demonstrates strong inhibitory effects on Gram-positive bacteria and weaker inhibition against certain Gram-negative bacteria and yeasts. Additionally, Saptomycin D shows significant antitumor properties that make it a candidate for research in cancer therapy.</p>

<p>Actinoidin A is a glycopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>

<p>Pexiganan, a synthetic magainin 2 analog, is a broad-spectrum antimicrobial peptide for researching infections like diabetic foot ulcers.</p>

<p>Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.</p>

<p>Cefquinome is a cephem antibiotic that inhibits Enterobacteriaceae (family [1]).</p>

<p>Efrotomycin: an oral antibiotic from Streptomyces Lactamdurans; minimal effect on Salmonella in pigs.</p>

<p>Sphinganine is a synthetic sphingolipid fungicide against C. glabrata and C. albicans; MFC 0.5 μg/ml. Used as an analysis standard.</p>

<p>Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-</p>

<p>Umirolimus, a sirolimus derivative, boosts anti-inflammatory/antiproliferative effects &amp; offers better pharmacokinetics.</p>

<p>Isocryptomerin, from Selaginella tamariscina, is an antifungal that depolarizes membranes and has anticancer, antibacterial effects.</p>

<p>A 83016A is a kinamycin-type antibiotic.</p>

<p>Cefotiam (SCE-963), a parenteral cephalosporin antibiotic, exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria [1] [2].</p>