Antibatterico

(+)-Thienamycin, a powerful broad-spectrum antibacterial and β-lactamase inhibitor, is isolated from Streptomyces cattleya [1].

Tuberculosis inhibitor 8 (compound 3b), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against both Mycobacterium

Bassianolide, a cyclodepsipeptide insecticide produced by the fungal species B. bassiana and V. lecanii, demonstrates significant biological activity. Upon oral administration, it induces atony in B. mori silkworms at a concentration of 4 ppm and becomes lethal when concentrations exceed 8 ppm. Remarkably, atony in silkworm larvae can also be triggered by doses as low as 2 µg/larva. Further studies reveal that bassianolide (0.01-1 µM) specifically targets muscarinic receptors to inhibit contractions in isolated guinea pig smooth muscle tissue, elicited by acetylcholine, without affecting nicotinic receptor-induced contractions.

MF 5137 is an effective antimicrobial agent.

Anti-MRSA Agent 8 (Compound 7g), a derivative of DAPG, exhibits potent antibacterial properties by interacting with bacterial cell membranes and is useful for

BMY-43748 is an antibacterial compound with great in vitro and in vivo antibacterial activity.

Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections.

TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.

AG 85 is a major secretion protein of Mycobacterium tuberculosis.

Ianthelliformisamine B TFA, an antibiotic enhancer, is used to against resistant Gram-negative bacteria.

Sulfisoxazole acetyl (Gantrisin) is an agent with antibacterial activity.

T145 halts key bacteria growth at sub μg/ml, deters resistance, and may enhance drug lifespan.

4-Aminosalicylic acid hemicalcium, an orally active antibiotic, shows potential in tuberculosis research [1].

DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].

Variculanol, a compound with antimicrobial, anticancer, and anti-HCV NS3/4A protease properties, is derived from the marine fungus Aspergillus versicolor [1].

Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron

BDM91270 (compound 29) serves as an inhibitor of the E.

L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.

Tylvalosin (Acetylisovaleryltylosin) is a broad-spectrum macrolide antibiotic with antibacterial and antiviral properties, effective against PRRSV infection.