Antibatterico

<p>Benzylpenicillin, a penicillin derivative, treats infections using sodium or potassium salts. Effective against gram-positive bacteria and gram-negative cocci.</p>

SPR720 disodium is an orally active and potent phosphate VXc-486 prodrug,has potent bactericidal activities in vivo.

Linopristin is a streptogramin B class antibiotic. It is one of the components of the antibiotic combination NXL103.

Psicofuranine: a nucleoside antibiotic inhibiting GMP synthase and P. falciparum growth with an IC50 of 0.3 mM.

PD-L1/LpxC-IN-1 (Compound 12b) is an inhibitor of PD-L1 and LpxC, with IC50 values of 5.2 μM and 0.081 μM, respectively. This compound disrupts bacterial lipopolysaccharide biosynthesis, leading to bacterial cell lysis and death. It effectively inhibits Gram-negative bacteria, exhibiting a minimum inhibitory concentration (MIC) of 0.25-0.5 μg/mL against K. pneumoniae ATCC 13883, E. coli ATCC 8739, S. typhimurium ATCC 14028, and P. aeruginosa ATCC 9027. Additionally, PD-L1/LpxC-IN-1 modulates the immune response by downregulating the expression of inflammatory cytokines IL-2 and IFN-γ, and upregulating CD4+ and CD8+ cells, thus activating the immune system and mitigating excessive inflammatory responses. In a mouse model of K. pneumoniae ATCC 13883 infection, PD-L1/LpxC-IN-1 demonstrated antibacterial activity.

Antimicrobial agent-40 exhibits antibacterial activity against fungi, Gram-negative, and Gram-positive bacteria. It also shows anticancer properties, displaying significant cytotoxicity towards MCF-7 cells with an IC50 of 33.52 μM.

<p>Vitamin K5, a photosensitizer &amp; antimicrobial, inhibits PKM2, PKM1 &amp; PKL, induces apoptosis in colon cells, and preserves food &amp; medicine.</p>

Streptolydigin inhibits RNA synthesis by binding to RNA polymerase and does not inhibit eukaryotic RNA polymerases.

Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.

<p>Dehydrolycopene, a major SGA in tomatoes' green fruits, leaves, and flowers, targets bacteria, fungi, insects, and animals.</p>

Sparsomycin is an antitumor antibiotic. It also inhibits protein synthesis in the 70S and 80S ribosomal systems.

Cefsulodin, a β-lactam antibiotic, targets E. coli's penicillin-binding proteins, aiding with cell wall synthesis disruption.

Viomycin sulfate hydrate is an effective antimycobacterial antibiotic (antibiotic). It rapidly inhibits the elongation of polypeptide chains when added to purified endogenous polypeptide-synthesizing Escherichia coli polypeptide systems.

Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.

Phanerosporic acid, from P. chrysosporum, fights bacteria like B. cereus and fungi including C. cladosporioides; used in macrolide synthesis.

Pseudomonic acid D is a topical antibiotic agent used against superficial skin infections such as impetigo or folliculitis.

Amythiamicin C is an antimicrobial antibiotic effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and also exhibits activity against Plasmodium falciparum (the causative agent of malaria).

Citrullinated LL-37 3cit is a host defense peptide with potent immunomodulatory and antimicrobial properties, demonstrating direct antiviral activity against

Gramicidin B is a nonribosomal peptide with antibiotic properties [1].

Urechistachykinin I (Uru-TK I) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.