Antibatterico
Gli inibitori antibatterici sono composti che prendono di mira le cellule batteriche, inibendo la loro crescita o uccidendole direttamente. Questi inibitori sono essenziali nello sviluppo di trattamenti per le infezioni batteriche e sono ampiamente utilizzati nella ricerca per studiare la fisiologia batterica, i meccanismi di resistenza e l'efficacia di nuovi agenti antibatterici. Presso CymitQuimica offriamo una gamma di inibitori antibatterici per supportare la vostra ricerca in microbiologia, malattie infettive e sviluppo di farmaci.
Trovati 3334 prodotti di "Antibatterico"
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Fenbenicillin potassium
CAS:Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.Formula:C22H22KN2O5SColore e forma:SolidPeso molecolare:465.584Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formula:C16H11F2N3Colore e forma:SolidPeso molecolare:283.28OPC-167832
CAS:OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formula:C21H20ClF3N2O4Colore e forma:SolidPeso molecolare:456.84Kendomycin
CAS:Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formula:C29H42O6Colore e forma:SolidPeso molecolare:486.64AK-968-11563024
CAS:AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.Formula:C18H13I2N9O5Colore e forma:SolidPeso molecolare:689.162DNA Gyrase-IN-1
DNA Gyrase-IN-1: potent, selective promoter inhibitor. IC50: 2.6 μM, inhibits Mtb, MIC: 0.49 μM. Useful for tuberculosis research.Formula:C24H24FN7O6Colore e forma:SolidPeso molecolare:525.49GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formula:C13H20F3N5O8SColore e forma:SolidPeso molecolare:463.39Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formula:C18H18N4O5Colore e forma:SolidPeso molecolare:370.36Antifungal agent 27
Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.Formula:C18H23N5OSColore e forma:SolidPeso molecolare:357.47Lavendomycin
CAS:Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.Formula:C29H50N10O8Colore e forma:SolidPeso molecolare:666.77Antibacterial agent 88
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.Formula:C31H44N2O6SColore e forma:SolidPeso molecolare:572.76MtTMPK-IN-5
MtTMPK-IN-5 inhibits Mtb TMPK with IC50 of 34 μM and fights tuberculosis with MIC of 12.5 μM, aiding TB research.Formula:C21H23N5O2Colore e forma:SolidPeso molecolare:377.44MtTMPK-IN-8
MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.Formula:C24H24N6O7Colore e forma:SolidPeso molecolare:508.489-tert-Butyldoxycycline
CAS:9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.Formula:C26H32N2O8Colore e forma:SolidPeso molecolare:500.541LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Formula:C21H16ClN3O2Colore e forma:SolidPeso molecolare:377.82ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formula:C20H23N3O4Purezza:98%Colore e forma:SolidPeso molecolare:369.41Rf470 TFA
CAS:Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Formula:C28H31F3N4O7SColore e forma:SolidPeso molecolare:624.63Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Formula:C21H27N3SColore e forma:SolidPeso molecolare:353.52Nitrovin
CAS:Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.Formula:C14H12N6O6Colore e forma:SolidPeso molecolare:360.28Streptothricin F
CAS:Streptothricin F is a biochemical.Formula:C19H34N8O8Colore e forma:SolidPeso molecolare:502.52MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formula:C15H13N3O4SColore e forma:SolidPeso molecolare:331.35Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Formula:C16H35N3O2Colore e forma:SolidPeso molecolare:301.47Eravacycline
CAS:Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formula:C27H31FN4O8Purezza:97.46%Colore e forma:SolidPeso molecolare:558.56VEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.4(E)-2,6-Di-tertbutyl-4(4-(diethylamino)styryl)pyrylium TFA
CAS:(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium TFA (Compound 4a) functions as a Gram-negative outer membrane permeabilizer by targeting Met47 in LptA to disrupt LptA/LptC interactions, exhibiting synergistic antibacterial activity. This compound, when in the form of (trifluoromethanesulfonate), enhances the efficacy of pol B against both wild-type and multi-drug resistant A. baumannii and E. coli strains. Additionally, (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) serves as an adjuvant for antibiotics combating multi-drug resistant Gram-negative bacteria.Formula:C26H36F3NO4SColore e forma:SolidPeso molecolare:515.629BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formula:C25H30ClFN2OColore e forma:SolidPeso molecolare:428.97Apalcillin
CAS:Apalcillin (PC-904) combined with Ro 48-1220 (a penicillin sulfone β-lactamase inhibitor) exhibits broad-spectrum activity against Gram-negative aerobic and anaerobic bacteria, excluding Klebsiella acid-producing strains. This combination shows strong efficacy against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae with an effective MIC of 11 μg/mL. Additionally, it inhibits Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter at low MICs (0.25 to 4 μg/mL). However, it has limited efficacy against oxacillin-resistant staphylococci and some Gram-positive bacteria. Apalcillin/Ro 48-1220's effectiveness against certain extended-spectrum β-lactamase-producing Escherichia coli is comparable to piperacillin/tazobactam, though it is less effective against SHV-type β-lactamases.Formula:C25H23N5O6SPeso molecolare:521.55Ph-Ph+
Ph-Ph+ is a dimerized phenanthroline derivative with antitumor, antibacterial, and antifungal effects.Formula:C24H17N4Colore e forma:SolidPeso molecolare:361.42Mazethramycin
CAS:Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.
Formula:C17H19N3O4Peso molecolare:329.35PROTAC eDHFR Degrader-2
CAS:PROTACeDHFR Degrader-2 (compound 7b) is an effective degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), capable of reliably degrading eDHFR-tagged proteins.Formula:C34H40N8O9Peso molecolare:704.73Lapyrium chloride
CAS:Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formula:C21H35ClN2O3Peso molecolare:398.97Antibiofilm agent-4
CAS:Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.Formula:C15H15NO3Peso molecolare:257.287-APRA
CAS:7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formula:C10H12N2O3SPeso molecolare:240.28MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formula:C22H24N4O3Colore e forma:SolidPeso molecolare:392.45NDM-1 inhibitor-3
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.Formula:C16H12O4Purezza:99.67%Colore e forma:SolidPeso molecolare:268.26Ref: TM-T60454
1mg46,00€5mg87,00€10mg145,00€25mg279,00€50mg464,00€100mg677,00€500mg1.406,00€1mL*10mM (DMSO)95,00€Doxazosin impurity 12
CAS:Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.
Formula:C10H6O5SColore e forma:SolidPeso molecolare:238.217Lambertellin
CAS:Lambertellin, an effective antibiotic, acts as both a bactericide and fungicide. It exerts anti-inflammatory effects in LPS-stimulated RAW 264.7 macrophages by modulating the activation of MAPK and NF-κB signaling pathways.Formula:C14H8O5Colore e forma:SolidPeso molecolare:256.21Anti-MRSA agent 2
CAS:Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.Formula:C18H10Br2N2OColore e forma:SolidPeso molecolare:430.09Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Formula:C10H8BFO4Purezza:98%Colore e forma:SolidPeso molecolare:221.98(E)-Cefodizime
CAS:(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.Formula:C20H20N6O7S4Colore e forma:SolidPeso molecolare:584.669Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Formula:C20H12ClN3O5Colore e forma:SolidPeso molecolare:409.78PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formula:C17H18ClN3OSColore e forma:SolidPeso molecolare:347.86BAS-118
CAS:BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.Formula:C20H18N2O2Colore e forma:SolidPeso molecolare:318.369Cefamandole lithium
CAS:Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Formula:C18H17LiN6O5S2Colore e forma:SolidPeso molecolare:468.44MA220607
CAS:MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].Formula:C34H38INColore e forma:SolidPeso molecolare:587.58GSK-3036656 free base
CAS:GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.Formula:C10H13BClNO4Colore e forma:SolidPeso molecolare:257.48epi-D-Captopril
CAS:epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.Formula:C9H15NO3SColore e forma:SolidPeso molecolare:217.285Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formula:C20H18N2OColore e forma:SolidPeso molecolare:302.37Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formula:C16H23N3S2Colore e forma:SolidPeso molecolare:321.5NBTI 5463
CAS:NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Formula:C25H30N6O4Colore e forma:SolidPeso molecolare:478.547-Hydroxytropolone
CAS:7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formula:C16H27N5O3SColore e forma:SolidPeso molecolare:369.48Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formula:C7H14N3NaO8SColore e forma:SolidPeso molecolare:323.268-Deazafolic acid
CAS:8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formula:C20H20N6O6Purezza:98%Colore e forma:SolidPeso molecolare:440.41RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Formula:C12H10F2OColore e forma:SolidPeso molecolare:208.2Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formula:C17H10ClFN2Colore e forma:SolidPeso molecolare:296.73QPX7728 bis-acetoxy methyl ester
CAS:QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formula:C15H14BFO8Purezza:98%Colore e forma:SolidPeso molecolare:352.08PF 03709270
CAS:PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Formula:C19H27NO7S3Purezza:98%Colore e forma:SolidPeso molecolare:477.61NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formula:C22H24FN5O5SColore e forma:SolidPeso molecolare:489.52(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Formula:C28H35F3N4O3Colore e forma:SolidPeso molecolare:532.6MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formula:C23H18Cl2FNO3Colore e forma:SolidPeso molecolare:446.3HKI12134085
CAS:HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].
Formula:C18H18F3N3O5SColore e forma:SolidPeso molecolare:445.41Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Formula:C8H12N2S2Colore e forma:SolidPeso molecolare:200.32VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Formula:C20H18ClNO4Colore e forma:SolidPeso molecolare:371.81Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formula:C16H15N3O4Colore e forma:SolidPeso molecolare:313.31ZG297
CAS:ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.
Formula:C31H35F3N4O3Colore e forma:SolidPeso molecolare:568.63MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formula:C23H24ClN3O3Colore e forma:SolidPeso molecolare:425.91NFC nitro probe 1
CAS:NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.Formula:C19H19NO6Colore e forma:SolidPeso molecolare:357.357Probenecid sodium
CAS:Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.Formula:C13H18NNaO4SColore e forma:SolidPeso molecolare:307.341Anticaries agent-1
CAS:Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.Formula:C15H12O4Colore e forma:SolidPeso molecolare:256.253N-Cbz-L-Cysteine
CAS:N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].Formula:C11H13NO4SColore e forma:SolidPeso molecolare:255.29DC-159a
CAS:DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Formula:C21H23F2N3O40·5H2OColore e forma:SolidPeso molecolare:428.42952-Bromo-2'-methoxyacetophenone
CAS:2-Bromo-2'-methoxyacetophenone acts as an irreversible inhibitor of MurA, effectively inhibiting MurA in E. coli with an IC50 of 0.38 μM. This compound helps inhibit bacterial cell wall synthesis, making it useful in antimicrobial research.Formula:C9H9BrO2Peso molecolare:229.07D-CS319
CAS:D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formula:C7H11NO2S3Colore e forma:SolidPeso molecolare:237.36Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formula:C24H28FN5O8Colore e forma:SolidPeso molecolare:533.51FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Formula:C21H16ClF2NO2Colore e forma:SolidPeso molecolare:387.81BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formula:C26H33FN2O4SColore e forma:SolidPeso molecolare:488.61MBL-IN-5
CAS:MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formula:C20H16ClNO3Colore e forma:SolidPeso molecolare:353.80H052
CAS:H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.
Formula:C21H15ClFN3O4SColore e forma:SolidPeso molecolare:459.88Urease-IN-1
Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).Formula:C17H12BrFN4O2SColore e forma:SolidPeso molecolare:435.27Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formula:C22H28N6OColore e forma:SolidPeso molecolare:392.5RNAP-σ interaction inhibitor-1
CAS:RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.Formula:C19H11Cl3N2O6S2Colore e forma:SolidPeso molecolare:533.79AAA-10 formic
AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.Formula:C26H43FO7SColore e forma:SolidPeso molecolare:518.68Bilanafos
CAS:Bilanafos is an agent of Anti-Bacterial.Formula:C11H22N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:323.28DL-2-Aminopimelic Acid
CAS:DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.Formula:C7H13NO4Colore e forma:SolidPeso molecolare:175.18MK-3402
CAS:MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .Formula:C15H19N9O5S2Colore e forma:SolidPeso molecolare:469.50WQ3810
CAS:WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.Formula:C22H22F3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:461.44Palmitanilide
CAS:Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formula:C22H37NOColore e forma:SolidPeso molecolare:331.535Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Formula:C18H27N3O2S3Colore e forma:SolidPeso molecolare:413.62FG-2101
CAS:FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Formula:C30H32N5O6PColore e forma:SolidPeso molecolare:589.579Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Formula:C22H27N3OSColore e forma:SolidPeso molecolare:381.53BAR-072
CAS:BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Formula:C18H13N3O6Colore e forma:SolidPeso molecolare:367.312PCTR1
CAS:PCTR1, derived from DHA, hastens inflammation resolution and boosts macrophage function, reducing PGE2, PGD2, and TXB2 in mice.Formula:C32H47N3O9SColore e forma:SolidPeso molecolare:649.8Fabimycin
CAS:Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formula:C23H25ClN4O3Colore e forma:SolidPeso molecolare:440.92Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formula:C27H33Cl2FN4O8Purezza:95% - 99.68%Colore e forma:SolidPeso molecolare:631.48Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formula:C25H36N6O8SPurezza:99.85%Colore e forma:SolidPeso molecolare:580.65LeuRS-IN-1 hydrochloride
CAS:LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Formula:C10H14BCl2NO3Purezza:97.34% - 99.61%Colore e forma:SolidPeso molecolare:277.94Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formula:C12H15N5O9S2Purezza:97.71% - >99.99%Colore e forma:SolidPeso molecolare:437.41Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formula:C8H10N3NaO6SPurezza:97.01% - 99.03%Colore e forma:SolidPeso molecolare:299.23Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formula:C19H22N2O8Colore e forma:SolidPeso molecolare:406.39Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formula:C20H31NO4Purezza:98%Colore e forma:SolidPeso molecolare:349.46α-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formula:C10H18OPurezza:97.55%Colore e forma:Colorless LiquidPeso molecolare:154.25Ref: TM-FR14115
Prodotto fuori produzione2-Mercaptopyridine N-oxide sodium
CAS:2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Formula:C5H4NNaOSColore e forma:SolidPeso molecolare:149.14Zabofloxacin hydrochloride
CAS:Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Formula:C19H21ClFN5O4Purezza:98%Colore e forma:SolidPeso molecolare:437.86Sulfamonomethoxine sodium
CAS:Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Formula:C11H11N4NaO3SPurezza:98%Colore e forma:SolidPeso molecolare:302.29Lenampicillin hydrochloride
CAS:Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFormula:C21H24ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:497.95Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formula:C14H19N3OPurezza:98%Colore e forma:SolidPeso molecolare:245.32CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formula:C19H21Br2Cl2N3O2SColore e forma:SolidPeso molecolare:586.16Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formula:C26H44O8Purezza:98%Colore e forma:SolidPeso molecolare:484.62trans-Clopenthixol dihydrochloride
CAS:Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Formula:C22H27Cl3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:473.89l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formula:C23H31Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:436.42Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formula:C16H16FN3O3SColore e forma:SolidPeso molecolare:349.38N-Butylthiophosphoric triamide
CAS:N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Formula:C4H14N3PSColore e forma:SolidPeso molecolare:167.21Dusquetide
CAS:Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formula:C25H47N9O5Purezza:98%Colore e forma:SolidPeso molecolare:553.709N-(3-(Dimethylamino)propyl)tetradecanamide
CAS:N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Formula:C19H40N2OColore e forma:SolidPeso molecolare:312.542Cefadroxil (hydrate)
CAS:Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Formula:C16H19N3O6SColore e forma:White Crystalline SolidPeso molecolare:381.404MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formula:C23H22N2O7Purezza:98%Colore e forma:SolidPeso molecolare:438.43Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formula:C9H15NO3Colore e forma:SolidPeso molecolare:185.223PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formula:C24H20ClNO3Colore e forma:SolidPeso molecolare:405.87Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formula:C12H13NO5SColore e forma:SolidPeso molecolare:283.3Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formula:C18H26OColore e forma:SolidPeso molecolare:258.4Ciprofloxacin lactate
CAS:Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Formula:C20H24FN3O6Colore e forma:SolidPeso molecolare:421.43Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formula:C35H61NO12Purezza:98%Colore e forma:White Amorphous Powder SolidPeso molecolare:687.86Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formula:C21H28ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:501.98Cefetamet pivoxyl
CAS:Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Formula:C20H25N5O7S2Purezza:98%Colore e forma:SolidPeso molecolare:511.57FtsZ-IN-10
CAS:Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Formula:C15H13ClN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:352.79Pulcherriminic acid
CAS:Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Formula:C12H20N2O4Colore e forma:SolidPeso molecolare:256.301-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formula:C11H10OColore e forma:SolidPeso molecolare:158.21-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Formula:C14H11F2NO4Colore e forma:SolidPeso molecolare:295.2382Phosalacine
CAS:Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Formula:C14H28N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:365.367TP0586532
CAS:TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Formula:C26H28N4O4Purezza:98%Colore e forma:SolidPeso molecolare:460.52Methanesulfonyl Chloride-d3,13C
CAS:Formula:C2H3ClO2SColore e forma:Colourless OilPeso molecolare:118.56d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formula:C23H31Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:436.42Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formula:C21H21N7OSPurezza:98%Colore e forma:SolidPeso molecolare:419.5
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