Antibatterico
Gli inibitori antibatterici sono composti che prendono di mira le cellule batteriche, inibendo la loro crescita o uccidendole direttamente. Questi inibitori sono essenziali nello sviluppo di trattamenti per le infezioni batteriche e sono ampiamente utilizzati nella ricerca per studiare la fisiologia batterica, i meccanismi di resistenza e l'efficacia di nuovi agenti antibatterici. Presso CymitQuimica offriamo una gamma di inibitori antibatterici per supportare la vostra ricerca in microbiologia, malattie infettive e sviluppo di farmaci.
Trovati 3153 prodotti di "Antibatterico"
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Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Colore e forma:SolidPeso molecolare:443.41Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Formula:C19H24N2O4Colore e forma:SolidPeso molecolare:344.4NusB-IN-1
NusB-IN-1 (22r) is an oral bacterial rRNA inhibitor, effective against MRSA and VRSA.Formula:C21H16N2O3Colore e forma:SolidPeso molecolare:344.36Antibacterial agent 90
Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.Formula:C30H42N2O6Colore e forma:SolidPeso molecolare:526.66LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Formula:C21H16ClN3O2Colore e forma:SolidPeso molecolare:377.829-tert-Butyldoxycycline
CAS:<p>9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.</p>Formula:C26H32N2O8Colore e forma:SolidPeso molecolare:500.541Pneumolysin-IN-1
CAS:Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].Formula:C23H16Cl2N2O4Colore e forma:SolidPeso molecolare:455.29MtTMPK-IN-5
<p>MtTMPK-IN-5 inhibits Mtb TMPK with IC50 of 34 μM and fights tuberculosis with MIC of 12.5 μM, aiding TB research.</p>Formula:C21H23N5O2Colore e forma:SolidPeso molecolare:377.44Lavendomycin
CAS:Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.Formula:C29H50N10O8Colore e forma:SolidPeso molecolare:666.77Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formula:C30H35NO11Colore e forma:SolidPeso molecolare:585.60Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formula:C23H27N3O2SColore e forma:SolidPeso molecolare:409.54Squalamine lactate
CAS:Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Formula:C37H71N3O8SPurezza:98%Colore e forma:SolidPeso molecolare:718.04AK-968-11563024
CAS:<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formula:C18H13I2N9O5Colore e forma:SolidPeso molecolare:689.162MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formula:C15H19N9O5S2Colore e forma:SolidPeso molecolare:469.50FtsZ-IN-13
CAS:<p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>Formula:C18H14N2O4S2Colore e forma:SolidPeso molecolare:386.445Fenbenicillin potassium
CAS:<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Formula:C22H22KN2O5SColore e forma:SolidPeso molecolare:465.584Antibacterial agent 113
Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.Formula:C29H18ClN5OColore e forma:SolidPeso molecolare:487.94Antibacterial agent 259
CAS:Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.Formula:C7H6ClN3O2SColore e forma:SolidPeso molecolare:231.659Cilastatin ammonium salt
CAS:Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Formula:C16H29N3O5SColore e forma:SolidPeso molecolare:375.48Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Formula:C10H8BFO4Purezza:98%Colore e forma:SolidPeso molecolare:221.98Palmitanilide
CAS:Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formula:C22H37NOColore e forma:SolidPeso molecolare:331.535LasR antagonist 1
CAS:LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Formula:C20H15F3N2O3Colore e forma:SolidPeso molecolare:388.34K13787
CAS:<p>K13787 is an acetohydroxy acid synthase (AHAS) inhibitor with antibacterial properties. It exhibits antimicrobial activity against various non-tuberculous mycobacteria (NTM) as well as clarithromycin (CLR) resistant strains.</p>Formula:C14H11F2N5O4SColore e forma:SolidPeso molecolare:383.33JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formula:C19H20Cl2O2Colore e forma:SolidPeso molecolare:351.27ROS inducer 9
CAS:<p>ROS inducer 9 (compound 4e) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 0.25 μg/mL against Escherichia coli. It eradicates bacteria by inhibiting GSH activity and increasing ROS levels. Additionally, ROS inducer 9 exhibits low toxicity toward red blood cells and RAW 264.7 cells.</p>Formula:C26H26BrF4N3O3Colore e forma:SolidPeso molecolare:584.401Fostriecin (free base)
CAS:Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Formula:C19H27O9PColore e forma:SolidPeso molecolare:430.39BAR-072
CAS:<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Formula:C18H13N3O6Colore e forma:SolidPeso molecolare:367.312MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formula:C22H24N4O3Colore e forma:SolidPeso molecolare:392.45BAS-118
CAS:<p>BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.</p>Formula:C20H18N2O2Colore e forma:SolidPeso molecolare:318.369Metallo-β-lactamase-IN-13
CAS:<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Formula:C15H10F3N7O2S2Colore e forma:SolidPeso molecolare:441.41MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Formula:C34H38INColore e forma:SolidPeso molecolare:587.58Cefempidone
CAS:Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.Formula:C22H21N7O6S2Peso molecolare:543.58Antibacterial agent 68
Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.Formula:C26H25BrN4O7Colore e forma:SolidPeso molecolare:585.4trans-Clopenthixol
CAS:<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formula:C22H25ClN2OSColore e forma:SolidPeso molecolare:400.965Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formula:C17H23F3N8O10SColore e forma:SolidPeso molecolare:588.47BRD-4592
CAS:BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.Formula:C17H15FN2OColore e forma:SolidPeso molecolare:282.312Pks13-TE inhibitor 4
CAS:<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formula:C26H25N5O6Peso molecolare:503.51RCB18350
CAS:<p>RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.</p>Formula:C19H18F3N3O4SColore e forma:SolidPeso molecolare:441.424PKZ18
CAS:PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.Formula:C22H26N2O3SColore e forma:SolidPeso molecolare:398.518Antibacterial agent 266
CAS:Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.Formula:C13H11N3OColore e forma:SolidPeso molecolare:225.246HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Formula:C7H4N2O4S2Colore e forma:SolidPeso molecolare:244.248DNA Gyrase-IN-13
CAS:<p>DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.</p>Formula:C15H21N3O3SColore e forma:SolidPeso molecolare:323.41Kikumycin A
CAS:<p>Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.</p>Formula:C13H17N7O2Colore e forma:SolidPeso molecolare:303.32Antibacterial agent 261
CAS:Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).Formula:C18H24N4O3S2Colore e forma:SolidPeso molecolare:408.538MT0703
CAS:MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.Formula:C26H25N7O9S3Colore e forma:SolidPeso molecolare:675.71epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Formula:C9H15NO3SColore e forma:SolidPeso molecolare:217.285Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formula:C16H15N3O4Colore e forma:SolidPeso molecolare:313.31Antibacterial agent 174
CAS:<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Formula:C25H30FN2NaO5Colore e forma:SolidPeso molecolare:480.5Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formula:C16H23N3S2Colore e forma:SolidPeso molecolare:321.5KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Formula:C12H10BN3O2SColore e forma:SolidPeso molecolare:271.17-APRA
CAS:7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.Formula:C10H12N2O3SPeso molecolare:240.28Benzisothiazolone
CAS:Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Formula:C7H5NOSColore e forma:SolidPeso molecolare:151.19Aurantiogliocladin
CAS:<p>Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.</p>Formula:C10H12O4Colore e forma:SolidPeso molecolare:196.2MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formula:C23H24ClN3O3Colore e forma:SolidPeso molecolare:425.91QPX7728 bis-acetoxy methyl ester
CAS:QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formula:C15H14BFO8Purezza:98%Colore e forma:SolidPeso molecolare:352.08Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formula:C19H25N9O3Colore e forma:SolidPeso molecolare:427.46LolCDE-IN-2
CAS:<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formula:C22H17N5OPurezza:98%Colore e forma:SolidPeso molecolare:367.40Metallo-β-lactamase-IN-16
CAS:Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Formula:C16H16N8O4S3Colore e forma:SolidPeso molecolare:480.54Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formula:C17H10ClFN2Colore e forma:SolidPeso molecolare:296.73Lapyrium chloride
CAS:Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formula:C21H35ClN2O3Peso molecolare:398.97Alpibectir
CAS:<p>Alpibectir has antibacterial activity [1].</p>Formula:C12H14F6N2O2Colore e forma:SolidPeso molecolare:332.24OPC-167832
CAS:OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formula:C21H20ClF3N2O4Colore e forma:SolidPeso molecolare:456.84Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formula:C24H33BrN2O2Colore e forma:SolidPeso molecolare:461.44Antibacterial agent 236
CAS:<p>Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.</p>Formula:C26H27N5O2SColore e forma:SolidPeso molecolare:473.59Mazethramycin
CAS:<p>Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.</p>Formula:C17H19N3O4Peso molecolare:329.35Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Colore e forma:SolidPeso molecolare:468.453Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formula:C15H10F3N3OSColore e forma:SolidPeso molecolare:337.32Kalafungin
CAS:Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Formula:C16H12O6Colore e forma:SolidPeso molecolare:300.26β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Formula:C21H17Cl3O7Colore e forma:SolidPeso molecolare:487.71MtTMPK-IN-8
<p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>Formula:C24H24N6O7Colore e forma:SolidPeso molecolare:508.48Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Formula:C25H18N2O2SColore e forma:SolidPeso molecolare:410.49Pisiferic acid
CAS:<p>Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoid</p>Formula:C20H28O3Colore e forma:SolidPeso molecolare:316.43Gepotidacin hydrochloride
CAS:Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Formula:C24H29ClN6O3Colore e forma:SolidPeso molecolare:484.98Eravacycline
CAS:Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Formula:C27H31FN4O8Purezza:97.46%Colore e forma:SolidPeso molecolare:558.56ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formula:C20H23N3O4Purezza:98%Colore e forma:SolidPeso molecolare:369.41MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Formula:C27H29ClN6O3Colore e forma:SolidPeso molecolare:521.01844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Formula:C24H25F3N4O2Colore e forma:SolidPeso molecolare:458.48AVE-1330A sodium
CAS:AVE-1330A sodium is a beta-Lactamase inhibitor.Formula:C7H10N3NaO6SColore e forma:SolidPeso molecolare:287.23MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Peso molecolare:373.18Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColore e forma:SolidPeso molecolare:238.217Keto lovastatin
CAS:Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formula:C24H34O6Colore e forma:SolidPeso molecolare:418.523RNAP-σ interaction inhibitor-2
CAS:RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formula:C27H19Cl3N2O6S2Colore e forma:SolidPeso molecolare:637.939Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formula:C22H21ClN2O8Colore e forma:SolidPeso molecolare:476.86Ro 24-4383
CAS:Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Formula:C32H31FN8O10S2Purezza:98%Colore e forma:SolidPeso molecolare:770.76Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formula:C21H18ClN3O7SColore e forma:SolidPeso molecolare:491.902Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formula:C16H11F2N3Colore e forma:SolidPeso molecolare:283.28MBL-IN-5
CAS:MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formula:C20H16ClNO3Colore e forma:SolidPeso molecolare:353.80Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Formula:C14H21N3S2Colore e forma:SolidPeso molecolare:295.47SPR719
CAS:SPR719 is an inhibitor of gyrase B, has bactericidal activity.Formula:C21H25FN6O3Purezza:98%Colore e forma:SolidPeso molecolare:428.46(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formula:C12H14N2O5Colore e forma:SolidPeso molecolare:266.25Antibacterial agent 279
CAS:Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.Formula:C9H11NO2SColore e forma:SolidPeso molecolare:197.25H052
CAS:<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Formula:C21H15ClFN3O4SColore e forma:SolidPeso molecolare:459.882'-Amino-2'-deoxyadenosine
CAS:<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Formula:C10H14N6O3Peso molecolare:266.264-Bromo A23187
CAS:4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Formula:C29H36BrN3O6Purezza:98%Colore e forma:SolidPeso molecolare:602.52Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Formula:C29H18BrN3O2Colore e forma:SolidPeso molecolare:520.386Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formula:C23H24N6OColore e forma:SolidPeso molecolare:400.48Aquayamycin
CAS:Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Formula:C25H26O10Colore e forma:SolidPeso molecolare:486.47Antibacterial agent 99
CAS:Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Formula:C27H27BrN2Colore e forma:SolidPeso molecolare:459.42Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formula:C31H34N2O7Colore e forma:SolidPeso molecolare:546.61Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Formula:C18H18N4O5Colore e forma:SolidPeso molecolare:370.36Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formula:C25H33NO2Colore e forma:SolidPeso molecolare:379.535NBTI 5463
CAS:NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Formula:C25H30N6O4Colore e forma:SolidPeso molecolare:478.54TBAJ-5307
CAS:TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Formula:C30H35BrN4O6Colore e forma:SolidPeso molecolare:627.53(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at aFormula:C28H35F3N4O3Colore e forma:SolidPeso molecolare:532.6OSUAB-0284
CAS:OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.Formula:C22H23FN6O6Colore e forma:SolidPeso molecolare:486.45NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Formula:C24H25F3N4O2Colore e forma:SolidPeso molecolare:458.48Diclosulam
CAS:Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Formula:C13H10Cl2FN5O3SColore e forma:SolidPeso molecolare:406.22Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Formula:C14H11N5O4S2Colore e forma:SolidPeso molecolare:377.4BDM91288
CAS:BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].Formula:C17H22ClN5Colore e forma:SolidPeso molecolare:331.84Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Colore e forma:SolidPeso molecolare:322.093Metallo-β-lactamase-IN-14
CAS:<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Formula:C20H22N8O2S2Colore e forma:SolidPeso molecolare:470.57Kendomycin
CAS:Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formula:C29H42O6Colore e forma:SolidPeso molecolare:486.64L 689065
CAS:L 689065 is a 5-lipoxygenase inhibitor.Formula:C35H33ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:597.17RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formula:C22H26BrN5O4SColore e forma:SolidPeso molecolare:536.44MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Formula:C25H26N6O7Colore e forma:SolidPeso molecolare:522.51LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Formula:C10H14BCl2NO3Purezza:97.34% - 99.61%Colore e forma:SolidPeso molecolare:277.94Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formula:C25H36N6O8SPurezza:99.85%Colore e forma:SolidPeso molecolare:580.65Tigemonam
CAS:<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Formula:C12H15N5O9S2Purezza:99.03% - >99.99%Colore e forma:SolidPeso molecolare:437.41Eravacycline dihydrochloride
CAS:<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Formula:C27H33Cl2FN4O8Purezza:94.59% - 95%Colore e forma:SolidPeso molecolare:631.48Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formula:C8H10N3NaO6SPurezza:97.01% - 99.03%Colore e forma:SolidPeso molecolare:299.23Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Formula:C20H31NO4Purezza:98%Colore e forma:SolidPeso molecolare:349.46Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formula:C19H22N2O8Colore e forma:SolidPeso molecolare:406.39α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Formula:C10H18OPurezza:97.55%Colore e forma:Colorless LiquidPeso molecolare:154.25Ref: TM-FR14115
Prodotto fuori produzionetrans-Clopenthixol dihydrochloride
CAS:<p>Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].</p>Formula:C22H27Cl3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:473.89Pulcherriminic acid
CAS:<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Formula:C12H20N2O4Colore e forma:SolidPeso molecolare:256.30l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Formula:C23H31Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:436.42Zabofloxacin hydrochloride
CAS:<p>Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.</p>Formula:C19H21ClFN5O4Purezza:98%Colore e forma:SolidPeso molecolare:437.861-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Formula:C11H10OColore e forma:SolidPeso molecolare:158.2Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Formula:C35H61NO12Purezza:98%Colore e forma:White Amorphous Powder SolidPeso molecolare:687.86Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Formula:C21H28ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:501.982-Mercaptopyridine N-oxide sodium
CAS:<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Formula:C5H4NNaOSColore e forma:SolidPeso molecolare:149.14Phosalacine
CAS:<p>Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.</p>Formula:C14H28N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:365.367PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Formula:C24H20ClNO3Colore e forma:SolidPeso molecolare:405.87CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Formula:C19H21Br2Cl2N3O2SColore e forma:SolidPeso molecolare:586.16Dusquetide
CAS:Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Formula:C25H47N9O5Purezza:98%Colore e forma:SolidPeso molecolare:553.709Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Formula:C12H13NO5SColore e forma:SolidPeso molecolare:283.3FtsZ-IN-10
CAS:<p>Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.</p>Formula:C15H13ClN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:352.79Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Formula:C14H19N3OPurezza:98%Colore e forma:SolidPeso molecolare:245.32Lenampicillin hydrochloride
CAS:<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Formula:C21H24ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:497.95Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formula:C18H26OColore e forma:SolidPeso molecolare:258.4Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Formula:C16H16FN3O3SColore e forma:SolidPeso molecolare:349.38Sulfamonomethoxine sodium
CAS:<p>Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].</p>Formula:C11H11N4NaO3SPurezza:98%Colore e forma:SolidPeso molecolare:302.29Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Formula:C26H44O8Purezza:98%Colore e forma:SolidPeso molecolare:484.62MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Formula:C23H22N2O7Purezza:98%Colore e forma:SolidPeso molecolare:438.43N-Butylthiophosphoric triamide
CAS:<p>N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.</p>Formula:C4H14N3PSColore e forma:SolidPeso molecolare:167.21Cefadroxil (hydrate)
CAS:<p>Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.</p>Formula:C16H19N3O6SColore e forma:White Crystalline SolidPeso molecolare:381.404Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Formula:C9H15NO3Colore e forma:SolidPeso molecolare:185.223Cefetamet pivoxyl
CAS:<p>Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].</p>Formula:C20H25N5O7S2Purezza:98%Colore e forma:SolidPeso molecolare:511.57Ciprofloxacin lactate
CAS:<p>Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.</p>Formula:C20H24FN3O6Colore e forma:SolidPeso molecolare:421.43TP0586532
CAS:<p>TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.</p>Formula:C26H28N4O4Purezza:98%Colore e forma:SolidPeso molecolare:460.52Methanesulfonyl Chloride-d3,13C
CAS:Formula:C2H3ClO2SColore e forma:Colourless OilPeso molecolare:118.56d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Formula:C23H31Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:436.42Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formula:C21H21N7OSPurezza:98%Colore e forma:SolidPeso molecolare:419.5
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