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Antibatterico

Antibatterico

Gli inibitori antibatterici sono composti che prendono di mira le cellule batteriche, inibendo la loro crescita o uccidendole direttamente. Questi inibitori sono essenziali nello sviluppo di trattamenti per le infezioni batteriche e sono ampiamente utilizzati nella ricerca per studiare la fisiologia batterica, i meccanismi di resistenza e l'efficacia di nuovi agenti antibatterici. Presso CymitQuimica offriamo una gamma di inibitori antibatterici per supportare la vostra ricerca in microbiologia, malattie infettive e sviluppo di farmaci.

Trovati 2949 prodotti di "Antibatterico"

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  • Anti-MRSA agent 6


    <p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>
    Formula:C16H11F2N3
    Colore e forma:Solid
    Peso molecolare:283.28
  • HldA/E-IN-1

    CAS:
    <p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>
    Formula:C8H17FO13P2
    Colore e forma:Solid
    Peso molecolare:402.16
  • Antibacterial agent 259

    CAS:
    <p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>
    Formula:C7H6ClN3O2S
    Colore e forma:Solid
    Peso molecolare:231.659
  • MsbA-IN-4


    <p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>
    Formula:C23H18Cl2FN5O
    Colore e forma:Solid
    Peso molecolare:470.33
  • MsbA-IN-5


    <p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>
    Formula:C23H19Cl2N5O
    Colore e forma:Solid
    Peso molecolare:452.34
  • Antibiofilm agent-14

    CAS:
    <p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>
    Formula:C26H30ClN3O
    Colore e forma:Solid
    Peso molecolare:435.989
  • Kendomycin

    CAS:
    <p>Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.</p>
    Formula:C29H42O6
    Colore e forma:Solid
    Peso molecolare:486.64
  • Fenbenicillin potassium

    CAS:
    <p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>
    Formula:C22H22KN2O5S
    Colore e forma:Solid
    Peso molecolare:465.584
  • Antimicrobial agent-38

    CAS:
    <p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>
    Formula:C14H11N3O4S
    Colore e forma:Solid
    Peso molecolare:317.32
  • Antibacterial agent 76


    <p>Antibacterial agent 76 (compound 9) is a potent antibacterial agent.</p>
    Formula:C23H27N3O2S
    Colore e forma:Solid
    Peso molecolare:409.54
  • Antitubercular agent-13


    <p>Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.</p>
    Formula:C18H18N4O5
    Colore e forma:Solid
    Peso molecolare:370.36
  • FtsZ-IN-13

    CAS:
    <p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>
    Formula:C18H14N2O4S2
    Colore e forma:Solid
    Peso molecolare:386.445
  • MRL-494


    <p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>
    Formula:C26H35FN16O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:622.66
  • MtTMPK-IN-7


    <p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>
    Formula:C27H29ClN6O3
    Colore e forma:Solid
    Peso molecolare:521.01
  • Antifungal agent 38


    <p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>
    Formula:C8H12N2S2
    Colore e forma:Solid
    Peso molecolare:200.32
  • DC-159a

    CAS:
    <p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>
    Formula:C21H23F2N3O40·5H2O
    Colore e forma:Solid
    Peso molecolare:428.4295
  • Anticaries agent-1

    CAS:
    <p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>
    Formula:C15H12O4
    Colore e forma:Solid
    Peso molecolare:256.253
  • (R)-ZG197


    <p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) &amp; Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>
    Formula:C28H35F3N4O3
    Colore e forma:Solid
    Peso molecolare:532.6
  • MtTMPK-IN-8


    <p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>
    Formula:C24H24N6O7
    Colore e forma:Solid
    Peso molecolare:508.48
  • Tuberculosis inhibitor 5


    <p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>
    Formula:C25H18N2O2S
    Colore e forma:Solid
    Peso molecolare:410.49
  • ACHN-975

    CAS:
    <p>ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.</p>
    Formula:C20H23N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:369.41
  • Eravacycline

    CAS:
    <p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>
    Formula:C27H31FN4O8
    Purezza:97.46%
    Colore e forma:Solid
    Peso molecolare:558.56
  • Cetefloxacin

    CAS:
    <p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>
    Formula:C20H16F3N3O3
    Peso molecolare:403.35
  • QPX7728 bis-acetoxy methyl ester

    CAS:
    <p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>
    Formula:C15H14BFO8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:352.08
  • Glutamate-5-kinase-IN-2


    <p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>
    Formula:C17H10ClFN2
    Colore e forma:Solid
    Peso molecolare:296.73
  • Atramycin A

    CAS:
    <p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>
    Formula:C25H24O9
    Colore e forma:Solid
    Peso molecolare:468.453
  • Ro 24-4383

    CAS:
    <p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>
    Formula:C32H31FN8O10S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:770.76
  • Antibacterial agent 99

    CAS:
    <p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>
    Formula:C27H27BrN2
    Colore e forma:Solid
    Peso molecolare:459.42
  • MK-3402

    CAS:
    <p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>
    Formula:C15H19N9O5S2
    Colore e forma:Solid
    Peso molecolare:469.50
  • BioA-IN-1

    CAS:
    <p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>
    Formula:C18H17NO3S
    Colore e forma:Solid
    Peso molecolare:327.397
  • Asukamycin

    CAS:
    <p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>
    Formula:C31H34N2O7
    Colore e forma:Solid
    Peso molecolare:546.61
  • Aurachin C

    CAS:
    <p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>
    Formula:C25H33NO2
    Colore e forma:Solid
    Peso molecolare:379.535
  • Antibacterial agent 172

    CAS:
    <p>Antibacterial Agent 172 (Compound 6a), a &lt;i&gt;Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>
    Formula:C21H21N9O5S2
    Colore e forma:Solid
    Peso molecolare:543.58
  • (S)-ZG197


    <p>(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at a</p>
    Formula:C28H35F3N4O3
    Colore e forma:Solid
    Peso molecolare:532.6
  • Thiolactomycin

    CAS:
    <p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>
    Formula:C11H14O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:210.29
  • Mt KARI-IN-1


    <p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>
    Formula:C14H11N5O4S2
    Colore e forma:Solid
    Peso molecolare:377.4
  • Anti-MRSA agent 3

    CAS:
    <p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>
    Formula:C29H18BrN3O2
    Colore e forma:Solid
    Peso molecolare:520.386
  • Xeruborbactam isoboxil

    CAS:
    <p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>
    Formula:C15H16BFO6
    Colore e forma:Solid
    Peso molecolare:322.093
  • L 689065

    CAS:
    <p>L 689065 is a 5-lipoxygenase inhibitor.</p>
    Formula:C35H33ClN2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:597.17
  • Pks13-TE inhibitor 4

    CAS:
    <p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>
    Formula:C26H25N5O6
    Peso molecolare:503.51
  • NDM-1 inhibitor-3


    <p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>
    Formula:C16H12O4
    Purezza:98.66%
    Colore e forma:Solid
    Peso molecolare:268.26
  • 844-TFM


    <p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>
    Formula:C24H25F3N4O2
    Colore e forma:Solid
    Peso molecolare:458.48
  • Anti-MRSA agent 2

    CAS:
    <p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>
    Formula:C18H10Br2N2O
    Colore e forma:Solid
    Peso molecolare:430.09
  • OPC-167832

    CAS:
    <p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>
    Formula:C21H20ClF3N2O4
    Colore e forma:Solid
    Peso molecolare:456.84
  • Antibiotic U 44590

    CAS:
    <p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>
    Formula:C9H15N3O5
    Colore e forma:Solid
    Peso molecolare:245.23
  • Urease-IN-1


    <p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>
    Formula:C17H12BrFN4O2S
    Colore e forma:Solid
    Peso molecolare:435.27
  • Antibacterial agent 75


    <p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>
    Formula:C22H28N6O
    Colore e forma:Solid
    Peso molecolare:392.5
  • Urease-IN-20

    CAS:
    <p>Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 μM for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and γH2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.</p>
    Formula:C14H8FNO2Se
    Colore e forma:Solid
    Peso molecolare:320.18
  • RNAP-σ interaction inhibitor-1

    CAS:
    <p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>
    Formula:C19H11Cl3N2O6S2
    Colore e forma:Solid
    Peso molecolare:533.79
  • WQ3810

    CAS:
    <p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>
    Formula:C22H22F3N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:461.44