Antibatterico
Gli inibitori antibatterici sono composti che prendono di mira le cellule batteriche, inibendo la loro crescita o uccidendole direttamente. Questi inibitori sono essenziali nello sviluppo di trattamenti per le infezioni batteriche e sono ampiamente utilizzati nella ricerca per studiare la fisiologia batterica, i meccanismi di resistenza e l'efficacia di nuovi agenti antibatterici. Presso CymitQuimica offriamo una gamma di inibitori antibatterici per supportare la vostra ricerca in microbiologia, malattie infettive e sviluppo di farmaci.
Trovati 3334 prodotti di "Antibatterico"
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7-Hydroxytropolone
CAS:7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formula:C16H27N5O3SColore e forma:SolidPeso molecolare:369.48Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formula:C7H14N3NaO8SColore e forma:SolidPeso molecolare:323.268-Deazafolic acid
CAS:8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formula:C20H20N6O6Purezza:98%Colore e forma:SolidPeso molecolare:440.41RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Formula:C12H10F2OColore e forma:SolidPeso molecolare:208.2Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formula:C17H10ClFN2Colore e forma:SolidPeso molecolare:296.73QPX7728 bis-acetoxy methyl ester
CAS:QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Formula:C15H14BFO8Purezza:98%Colore e forma:SolidPeso molecolare:352.08PF 03709270
CAS:PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Formula:C19H27NO7S3Purezza:98%Colore e forma:SolidPeso molecolare:477.61NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formula:C22H24FN5O5SColore e forma:SolidPeso molecolare:489.52(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Formula:C28H35F3N4O3Colore e forma:SolidPeso molecolare:532.6MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Formula:C23H18Cl2FNO3Colore e forma:SolidPeso molecolare:446.3HKI12134085
CAS:HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].
Formula:C18H18F3N3O5SColore e forma:SolidPeso molecolare:445.41Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Formula:C8H12N2S2Colore e forma:SolidPeso molecolare:200.32VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Formula:C20H18ClNO4Colore e forma:SolidPeso molecolare:371.81Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Formula:C16H15N3O4Colore e forma:SolidPeso molecolare:313.31ZG297
CAS:ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.
Formula:C31H35F3N4O3Colore e forma:SolidPeso molecolare:568.63MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Formula:C23H24ClN3O3Colore e forma:SolidPeso molecolare:425.91NFC nitro probe 1
CAS:NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.Formula:C19H19NO6Colore e forma:SolidPeso molecolare:357.357Probenecid sodium
CAS:Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.Formula:C13H18NNaO4SColore e forma:SolidPeso molecolare:307.341Anticaries agent-1
CAS:Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.Formula:C15H12O4Colore e forma:SolidPeso molecolare:256.253N-Cbz-L-Cysteine
CAS:N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].Formula:C11H13NO4SColore e forma:SolidPeso molecolare:255.29DC-159a
CAS:DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Formula:C21H23F2N3O40·5H2OColore e forma:SolidPeso molecolare:428.42952-Bromo-2'-methoxyacetophenone
CAS:2-Bromo-2'-methoxyacetophenone acts as an irreversible inhibitor of MurA, effectively inhibiting MurA in E. coli with an IC50 of 0.38 μM. This compound helps inhibit bacterial cell wall synthesis, making it useful in antimicrobial research.Formula:C9H9BrO2Peso molecolare:229.07D-CS319
CAS:D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Formula:C7H11NO2S3Colore e forma:SolidPeso molecolare:237.36Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formula:C24H28FN5O8Colore e forma:SolidPeso molecolare:533.51FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Formula:C21H16ClF2NO2Colore e forma:SolidPeso molecolare:387.81BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formula:C26H33FN2O4SColore e forma:SolidPeso molecolare:488.61MBL-IN-5
CAS:MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Formula:C20H16ClNO3Colore e forma:SolidPeso molecolare:353.80H052
CAS:H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.
Formula:C21H15ClFN3O4SColore e forma:SolidPeso molecolare:459.88Urease-IN-1
Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).Formula:C17H12BrFN4O2SColore e forma:SolidPeso molecolare:435.27Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formula:C22H28N6OColore e forma:SolidPeso molecolare:392.5RNAP-σ interaction inhibitor-1
CAS:RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.Formula:C19H11Cl3N2O6S2Colore e forma:SolidPeso molecolare:533.79AAA-10 formic
AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.Formula:C26H43FO7SColore e forma:SolidPeso molecolare:518.68Bilanafos
CAS:Bilanafos is an agent of Anti-Bacterial.Formula:C11H22N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:323.28DL-2-Aminopimelic Acid
CAS:DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.Formula:C7H13NO4Colore e forma:SolidPeso molecolare:175.18MK-3402
CAS:MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .Formula:C15H19N9O5S2Colore e forma:SolidPeso molecolare:469.50WQ3810
CAS:WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.Formula:C22H22F3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:461.44Palmitanilide
CAS:Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.Formula:C22H37NOColore e forma:SolidPeso molecolare:331.535Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Formula:C18H27N3O2S3Colore e forma:SolidPeso molecolare:413.62FG-2101
CAS:FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Formula:C30H32N5O6PColore e forma:SolidPeso molecolare:589.579Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Formula:C22H27N3OSColore e forma:SolidPeso molecolare:381.53BAR-072
CAS:BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Formula:C18H13N3O6Colore e forma:SolidPeso molecolare:367.312PCTR1
CAS:PCTR1, derived from DHA, hastens inflammation resolution and boosts macrophage function, reducing PGE2, PGD2, and TXB2 in mice.Formula:C32H47N3O9SColore e forma:SolidPeso molecolare:649.8Fabimycin
CAS:Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formula:C23H25ClN4O3Colore e forma:SolidPeso molecolare:440.92Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formula:C27H33Cl2FN4O8Purezza:95% - 99.68%Colore e forma:SolidPeso molecolare:631.48Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formula:C25H36N6O8SPurezza:99.85%Colore e forma:SolidPeso molecolare:580.65LeuRS-IN-1 hydrochloride
CAS:LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Formula:C10H14BCl2NO3Purezza:97.34% - 99.61%Colore e forma:SolidPeso molecolare:277.94Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formula:C12H15N5O9S2Purezza:97.71% - >99.99%Colore e forma:SolidPeso molecolare:437.41Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Formula:C8H10N3NaO6SPurezza:97.01% - 99.03%Colore e forma:SolidPeso molecolare:299.23Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formula:C19H22N2O8Colore e forma:SolidPeso molecolare:406.39
