Antibatterico

CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and

Ro-23-9424, a cephalosporin with fleroxacin at 3' and aminothiazolylmethoxyimino at 7, exhibits strong broad-spectrum antibacterial effects.

LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide, a growth hormone-releasing peptide antagonist, and a GHS-R1a inverse agonist

Antibacterial agent 43 from patent WO2013030735A1 shows strong activity against infections and has research potential.

C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.

(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].

Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.

Framycetin is an aminoglycoside antibiotic and it also inhibits hammerhead ribozyme (Ki: 13.5 μM).

Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.

Adipic dihydrazide (ADH) is a dihydrazide a bifunctional cross-linking agent for water-in-oil emulsions and a curing agent for epoxy resins.

Isepamicin (Sch 21420) is a strong aminoglycoside antibiotic, effective on Enterobacteriaceae and staphylococci, less so on other bacteria.

Arylomycin B4 is a lipidic hexapeptide antibiotic (antibiotic) targeting Gram-positive bacteria.

Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.

Oxiran-2-ylmethanol exhibits antibacterial activity against Escherichia coli and can be used in related research in the field of life sciences.

Amoxycillin arginine salt is a bioactive chemical.

Omadacycline: an aminomethylcycline antibiotic, cidal against four Streptococcus pneumoniae strains.

Albocycline, a macrolide antibiotic from S. bruneogriseus MCRL-0129, targets staph including resistant strains.

Deacetylnomilin is a useful organic compound for research related to life sciences. The catalog number is T125039 and the CAS number is 3264-90-2.

Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.

Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.

Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.

Aibellin is a peptide antibiotic and serves as an effective and beneficial modulator of rumen fermentation.

Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.

4-Methoxycoumarine has antitumour effects.

Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria.

FPI-1523 inhibits β-lactamase (Kd: CTX-M-15 = 4 nM, OXA-48 = 34 nM), blocks PBP2 (IC50 = 3.2 μM), and has strong antimicrobial effects.

PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.

Tuberculosis inhibitor 9 (compound 3d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and

Antituberculosis agent-7: active against P. mirabilis (MIC 31.25μM), A. niger (MIC 62.5μM), and M. tuberculosis (MIC 3.41μM).

Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.

Gepotidacin S enantiomer is an S enantionmer of gepotidacin.

Azidocillin, a semi-synthetic oral β-lactam antibiotic, treats various bacterial infections including osteitis and septicemia.

Maximin 15, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with

N-3-oxo-hexadecanoyl-L-homoserine lactone, a C16 AHL, aids bacterial quorum sensing and primes plant systemic resistance.

Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.

Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.

XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.

Allolactose is a disaccharide used as an inducer of the lac operon in Escherichia coli and many other enteric bacteria.

D13-9001, an antibiotic, inhibits AcrB and MexB with KDs of 1.15μM in E. coli and 3.57μM in P. aeruginosa.

Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.

6-C-Methylquercetin-3,4'-dimethyl ether is a flavonol derivative extracted from Bauhinia thonningii Schum leaves, displaying antibacterial effects on Gram-

Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory

Ledaborbactam etzadroxil (VNRX-7145) is an orally active inhibitor of Ambler class A, C, and D β-lactamase enzymes.

GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.

Brilliant green: dye for silk/wool, inhibits mold, parasites, fungus, and kills Gram-positive bacteria.

Desacetylcefotaxime, a Cefotaxime metabolite, has strong antimicrobial effects against various bacteria.

Picromycin is a macrolide antibiotic and PREP inhibitor effective against gram-positive bacteria, including mycobacteria.

Antibacterial agent 150 (compound 5g) exhibits potent activity against a wide range of bacteria, including both Gram-positive and Gram-negative species, with

LBM-415 is a peptide deformylase (PDF) inhibitor.