Antibatterico

Moxifloxacin (Avelox), a 4th-gen fluoroquinolone, fights Gram-positive/negative bacteria and drug-resistant S. pneumoniae.

Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.

<p>Bagougeramine B is an orally active nucleoside antibiotic with antibacterial properties, discovered in Bacillus circulans. It inhibits the growth of both Gram-positive and Gram-negative bacteria, as well as some fungi.</p>

A 83016A is a kinamycin-type antibiotic.

FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs

Maximin 4, an antimicrobial peptide from Bombina maxima skin secretions, exhibits cytotoxic effects on tumor cells and spermicidal properties [1].

Sparsomycin is an antitumor antibiotic. It also inhibits protein synthesis in the 70S and 80S ribosomal systems.

<p>Compound PDK0270, with CAS No. 551-16-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0270 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.

Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd oxidase, acts as an antibiotic against malaria, Plasmodium spp.

Compound 12: potent antimicrobial with 2-8 μg/mL MIC, effective against Gram-positive/negative bacteria; anti-inflammatory.

Sperabillin A (free base) is a potent antibacterial antibiotic in vivo isolated from Pseudomonas fluorescens YK-437.

MMV1578877 is an inhibitor of Mycobacterium ulcerans with an IC50 of 0.37 μM. It is applicable in research related to Buruli ulcer (BU).

Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.

1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.

Amoxicillin + potassium clavulanate (4:1) is a broad-spectrum, well-absorbed oral antibiotic blocking cell wall synthesis.

Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.

Calcimycin (A-23187) is an antibiotic calcium ionophore that raises intracellular Ca2+ to induce cell death.

α-Lipomycin is an acyclic polyene antibiotic isolated from the Gram-positive bacterium Streptomyces aureofaciens Tü117.

Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.