HBV
Gli inibitori dell'HBV sono composti progettati per colpire e inibire varie fasi del ciclo vitale del virus dell'epatite B (HBV). Questi inibitori possono interferire con la replicazione virale, l'assemblaggio o il rilascio, riducendo così la carica virale e contribuendo a gestire le infezioni croniche da HBV. La ricerca sugli inibitori dell'HBV è fondamentale per sviluppare terapie antivirali efficaci per prevenire malattie epatiche e cancro associati all'HBV. Presso CymitQuimica, offriamo una gamma di inibitori dell'HBV per supportare la vostra ricerca in virologia, sviluppo di farmaci antivirali e gestione delle malattie infettive.
Trovati 187 prodotti di "HBV"
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Ibandronic acid
CAS:Ibandronic acid (Bonviva) is a third-generation amino-bisphosphonate with anti-resorptive and anti-hypercalcemic activities.Formula:C9H23NO7P2Purezza:94.84%Colore e forma:White Semi-SolidPeso molecolare:319.23Taribavirin hydrochloride
CAS:Taribavirin HCl: oral drug targeting HCV in liver, spares red blood cells, aims to reduce anemia risk.Formula:C8H14ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:279.68DVR-01
CAS:<p>DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.</p>Formula:C20H23ClN2O3SPurezza:99.95%Colore e forma:SolidPeso molecolare:406.93L-Fd4A
CAS:L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.Formula:C10H10FN5O2Colore e forma:SolidPeso molecolare:251.22BA-53038B
CAS:BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).Formula:C14H16ClNOColore e forma:SolidPeso molecolare:249.74Taribavirin
CAS:Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.Formula:C8H13N5O4Purezza:98%Colore e forma:SolidPeso molecolare:243.22RIG-1 modulator 1
CAS:RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.Formula:C14H17N5OS2Purezza:98%Colore e forma:SolidPeso molecolare:335.45NVP018
CAS:<p>NVP018 (BC 556) inhibits HBV, HCV, HIV-1 replication, barely affects drug transporters, and resists HCV/HIV-1 resistance development.</p>Formula:C45H62FN5O11Colore e forma:SolidPeso molecolare:868Bentysrepinine
CAS:Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.Formula:C29H35N3O4Purezza:98%Colore e forma:SolidPeso molecolare:489.61(-)-5′-Noraristeromycin
CAS:(-)-5′-Noraristeromycin is an antiviral agent.Formula:C10H13N5O3Colore e forma:SolidPeso molecolare:251.24Alamifovir
CAS:Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.Formula:C19H20F6N5O5PSColore e forma:SolidPeso molecolare:575.42HBV-IN-19
CAS:HBV-IN19 suppresses HBV, cutting HBsAg output, useful for chronic HBV study.Formula:C24H30N2O6Colore e forma:SolidPeso molecolare:442.5trans-ccc_R08
CAS:<p>trans-ccc_R08: potent cccDNA inhibitor, IC50 0.08 µM, may help research HBV.</p>Formula:C22H19ClO6Colore e forma:SolidPeso molecolare:414.84HBV-IN-7
CAS:<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 5 nM).</p>Formula:C18H17ClFN3O5S2Colore e forma:SolidPeso molecolare:473.93HBV-IN-9
CAS:HBV-IN-9 inhibits HBsAg (IC50: 10 nM) and HBV DNA replication (IC50: 0.15 nM) per WO2018001952A1.Formula:C22H24FN7OColore e forma:SolidPeso molecolare:421.47Clevudine triphosphate
CAS:Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate.Formula:C10H16FN2O14P3Purezza:98%Colore e forma:SolidPeso molecolare:500.16BA38017
CAS:BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].Formula:C15H11ClFNO3Colore e forma:SolidPeso molecolare:307.7Helioxanthin 8-1
CAS:Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.Formula:C20H12N2O6Purezza:98%Colore e forma:SolidPeso molecolare:376.32Bay 41-4109 (less active enantiomer)
CAS:Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).Formula:C18H13ClF3N3O2Purezza:98%Colore e forma:SolidPeso molecolare:395.76HBV-IN-6
CAS:HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).Formula:C23H21ClFN3O5S2Colore e forma:SolidPeso molecolare:538.01AB-506
CAS:AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.Formula:C21H18ClF2N5O3Colore e forma:SolidPeso molecolare:461.85(5S,8R)-HBV-IN-10
CAS:'(5S,8R)-HBV-IN-10 is an EC50 0.1-1 μM HBsAg inhibitor, isomer of compound 6 from patent WO2021204258A1.Formula:C23H24FN7OColore e forma:SolidPeso molecolare:433.48HBV-IN-29
CAS:HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.Formula:C22H19ClO6Colore e forma:SolidPeso molecolare:414.84HBV-IN-10
CAS:HBV-IN-10, an isomer of compound 6, inhibits HBsAg with EC50 between 0.1-1 μM (Patent WO2021204258A1).Formula:C23H24FN7OColore e forma:SolidPeso molecolare:433.48HBV-IN-32
CAS:HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.Formula:C22H19ClO5SColore e forma:SolidPeso molecolare:430.9cis-ccc_R08
CAS:cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .Formula:C22H19ClO6Colore e forma:SolidPeso molecolare:414.84HBV-IN-25
CAS:HBV-IN-25: oral HBV cccDNA reducer, anti-HBeAg, anti-HBV (IC50: 0.58/1.15 μM), soluble (>452 μg/mL), non-toxic.Formula:C18H14ClNO4Colore e forma:SolidPeso molecolare:343.76Fosclevudine alafenamide
CAS:Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent that acts against HBV (EC50: 1.71 μM).Formula:C22H29FN3O9PColore e forma:SolidPeso molecolare:529.45Lagociclovir
CAS:Lagociclovir (MIV-210), a nucleoside analogue antiviral, treats HBV by inhibiting its replication in liver cancer cells.Formula:C10H12FN5O3Purezza:99.18% - 99.74%Colore e forma:SolidPeso molecolare:269.23PPT
CAS:PPT is a modulator of water-heme interactions of CYP2C9d and CYP125A1 in low-spin P450 complexes.Formula:C11H13N3Purezza:98%Colore e forma:SolidPeso molecolare:187.24DVR-23
CAS:DVR-23 is a potent inhibitor of HBV virus.Formula:C17H17F3N2O3SColore e forma:SolidPeso molecolare:386.39BAY39-5493
CAS:BAY39-5493 is a hepatitis B virus inhibitor and possess antiviral activity in vitro and in vivo.Formula:C17H15ClFN3O2SColore e forma:SolidPeso molecolare:379.84LP10
CAS:LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.Formula:C24H28N4O2Colore e forma:SolidPeso molecolare:404.5Rolicyprine
CAS:Rolicyprine is an antidepressant.Formula:C14H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:244.29KKJ00626
CAS:KKJ00626, an inhibitor of HBV virus, inhibits HBV replication in transfected Huh7 cells.Formula:C7H8N4SPurezza:98%Colore e forma:SolidPeso molecolare:180.23Inarigivir
CAS:Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.Formula:C20H26N7O10PSPurezza:98%Colore e forma:SolidPeso molecolare:587.5Z060228
CAS:Z060228 is a potent anti-HBV agent, halts HBV DNA replication, and disrupts Cp149 self-assembly.Formula:C20H15ClF4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:426.79Ruzotolimod
CAS:Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections （WO2021130195A1）[1].Formula:C14H18N4O5SColore e forma:SolidPeso molecolare:354.38YZ51
CAS:YZ51, a novel potent inhibitor of ribonucleotide reductase (RR), inhibits hepatitis B virus replication by targeting ribonucleotide reductase M2 protein.Formula:C16H14FNO2Colore e forma:SolidPeso molecolare:271.29Vidarabine phosphate
CAS:Vidarabine phosphate is an adenosine monophosphate analog.Formula:C10H14N5O7PPurezza:99.75%Colore e forma:White Crystalline PowderPeso molecolare:347.22Bay 41-4109
CAS:BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).Formula:C18H13ClF3N3O2Colore e forma:SolidPeso molecolare:395.76Canocapavir
CAS:Canocapavir (ZM-H1505R) is an HBV coat protein modulator with antiviral activity for the treatment of hepatitis B virus.Formula:C27H21BrFN5O3Purezza:98.4% - 98.40%Colore e forma:SolidPeso molecolare:562.39Selgantolimod
CAS:Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.Formula:C14H20FN5OPurezza:98%Colore e forma:SolidPeso molecolare:293.34Helioxanthin derivative 5-4-2
CAS:<p>Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.</p>Formula:C20H13NO5Purezza:99.91% - 99.92%Colore e forma:SolidPeso molecolare:347.32Bersacapavir
CAS:Bersacapavir (JNJ-56136379) is an in vitro modulator of hepatitis B virus capsid assembly that inhibits HBV replication.Formula:C16H14F4N4O3SPurezza:98.53%Colore e forma:SolidPeso molecolare:418.37Pradefovir
CAS:Pradefovir (Remofovir) is a prodrug for chronic HBV, converting to PMEA in the liver with a Km of 60 μM and clearance of 359 ml/min.Formula:C17H19ClN5O4PPurezza:97.50%Colore e forma:SolidPeso molecolare:423.79Besifovir PM
<p>Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B</p>Formula:C11H15N5OPurezza:98.48% - 99.90%Colore e forma:SoildPeso molecolare:233.27Tivicilovir
CAS:Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.Formula:C9H13N5O3Purezza:99.94%Colore e forma:SolidPeso molecolare:239.23Isothiafludine
CAS:Isothiafludine is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells.Formula:C18H18FN3OS2Purezza:99.71%Colore e forma:SolidPeso molecolare:375.48Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFormula:C8H9FN3Na4O12P3SPurezza:98%Colore e forma:SolidPeso molecolare:575.11HBV-IN-41
CAS:HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].Formula:C18H19ClFN5O3Purezza:98%Colore e forma:SolidPeso molecolare:407.83Carbovir
CAS:Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.Formula:C11H13N5O2Colore e forma:SolidPeso molecolare:247.25Tobevibart
CAS:Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].Purezza:98%Colore e forma:LiquidHBV-IN-30
CAS:HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.Formula:C22H18BrClO6Colore e forma:SolidPeso molecolare:493.73Besifovir Dipivoxil maleate
CAS:Besifovir Dipivoxil maleate, an oral HBV prodrug (LB80380), suppresses HBV DNA in naive and lamivudine-resistant CHB cases.Formula:C22H34N5O8PPurezza:98%Colore e forma:SolidPeso molecolare:527.51HBV-IN-8
CAS:HBV-IN-6 is a potent inhibitor of HBV (EC50: 287.9 nM).Formula:C21H25ClFN5O5S2Colore e forma:SolidPeso molecolare:546.04Lagociclovir valactate
CAS:Lagociclovir valactate is a prodrug of Lagociclovir . Lagociclovir valactate is an orally active anti- HBV agent [1] .Formula:C18H25FN6O6Colore e forma:SolidPeso molecolare:440.43Valtorcitabine dihydrochloride
CAS:Valtorcitabine dihydrochloride, a DNA polymerase inhibitor, is used potentially for the treatment of HBV infection.Formula:C14H24Cl2N4O5Colore e forma:SolidPeso molecolare:399.27HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Formula:C16H12Cl2FN5Purezza:98.07% - 99.42%Colore e forma:SolidPeso molecolare:364.2SHR5133
CAS:SHR5133 is a potent, orally active regulator of HBV capsid assembly that reduces HBV DNA (EC50: 26.6 nM).Formula:C19H18F4N6O2Colore e forma:SolidPeso molecolare:438.38HEC72702
CAS:HEC72702: New HBV capsid inhibitor, from GLS4. No CYP1A2, CYP3A4, CYP2B6 induction at 10μM.Formula:C24H26BrFN4O5SColore e forma:SolidPeso molecolare:581.45HBV-IN-17
CAS:<p>HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM).</p>Formula:C17H15F6N5O2Colore e forma:SolidPeso molecolare:435.32Oxynitidine
CAS:Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].Formula:C21H17NO5Purezza:98%Colore e forma:SolidPeso molecolare:363.36HBV-IN-13
CAS:HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).Formula:C22H25NO7Colore e forma:SolidPeso molecolare:415.44IR415
CAS:IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBxFormula:C13H14F2N4SPurezza:99.85%Colore e forma:SolidPeso molecolare:296.34ent-Entecavir
CAS:Ent-Entecavir, an enantiomeric impurity of Entecavir (an oral HBV drug), inhibits HBV replication as a reverse transcriptase inhibitor.Formula:C12H15N5O3Colore e forma:SolidPeso molecolare:277.28AB-836
CAS:AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.Formula:C20H15F3N4O2Colore e forma:SolidPeso molecolare:400.35Tenofovir amibufenamide
CAS:Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。Formula:C22H31N6O5PPurezza:99.19% - 99.87%Colore e forma:SolidPeso molecolare:490.49Linvencorvir
CAS:<p>Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.</p>Formula:C29H35FN6O5SPurezza:99.9% - 99.9%Colore e forma:SolidPeso molecolare:598.69ALG-000184
CAS:<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formula:C23H20FN4Na2O8PColore e forma:SolidPeso molecolare:576.379HBV/HDV-IN-2
CAS:<p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>Formula:C38H44ClN7O5Colore e forma:SolidPeso molecolare:714.25HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Colore e forma:SolidHBV-IN-18
HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).Formula:C17H15F6N5O2Colore e forma:SolidPeso molecolare:435.32HBV-IN-31
CAS:HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.Formula:C23H18ClNO6Colore e forma:SolidPeso molecolare:439.85HBV-IN-11
CAS:HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).Formula:C21H24ClNO6Colore e forma:SolidPeso molecolare:421.87HBV-IN-19 TFA
CAS:HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.Formula:C26H31F3N2O8Colore e forma:SolidPeso molecolare:556.53HBV-IN-12
CAS:HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)Formula:C23H27NO8Colore e forma:SolidPeso molecolare:445.46TLR8 agonist 4
TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.Formula:C28H27N5O5SColore e forma:SolidPeso molecolare:545.61FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formula:C9H11FN6Na3O13P3Colore e forma:SolidPeso molecolare:592.11SAG-524
CAS:SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].Formula:C30H32ClN5O4SColore e forma:SolidPeso molecolare:594.12HBV-IN-48
CAS:HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.Formula:C22H15F4N3O3Colore e forma:SolidPeso molecolare:445.37HBV-IN-24
HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.Formula:C23H27NO6Colore e forma:SolidPeso molecolare:413.46CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Formula:C21H17ClF3N3O3SColore e forma:SolidPeso molecolare:483.89HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Formula:C28H27BrF3N5O3Colore e forma:SolidPeso molecolare:618.44HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Formula:C21H19F2N7Purezza:98%Colore e forma:SolidPeso molecolare:407.42Ref: TM-T79469
Prodotto fuori produzioneHBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Formula:C18H16F3N5O4S2Purezza:98%Colore e forma:SolidPeso molecolare:487.48Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Formula:C29H28ClFN6O3Purezza:98%Colore e forma:SolidPeso molecolare:563.02Ref: TM-T78756
Prodotto fuori produzione
