HBV
Gli inibitori dell'HBV sono composti progettati per colpire e inibire varie fasi del ciclo vitale del virus dell'epatite B (HBV). Questi inibitori possono interferire con la replicazione virale, l'assemblaggio o il rilascio, riducendo così la carica virale e contribuendo a gestire le infezioni croniche da HBV. La ricerca sugli inibitori dell'HBV è fondamentale per sviluppare terapie antivirali efficaci per prevenire malattie epatiche e cancro associati all'HBV. Presso CymitQuimica, offriamo una gamma di inibitori dell'HBV per supportare la vostra ricerca in virologia, sviluppo di farmaci antivirali e gestione delle malattie infettive.
Trovati 186 prodotti di "HBV"
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HBV-IN-24
HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.Formula:C23H27NO6Colore e forma:SolidPeso molecolare:413.46TLR7/8 agonist 13
CAS:TLR7/8 agonist 13 is an orally active dual agonist of TLR7 (with a lowest effective concentration (LEC) [hTLR7] of 1.6 μM) and TLR8 (LEC [hTLR8] of 1.6 μM). It acts on human peripheral blood mononuclear cells (hPBMC) with agonistic activity (LEC [hPBMC] = 0.5 μM). In mice and cynomolgus monkeys, TLR7/8 agonist 13 induces endogenous IFNα, activates myeloid dendritic cells and monocytes, promoting their differentiation towards a TH1 phenotype. In chronic AAV-HBV mouse models, it reduces viral load and HBV surface antigen levels. TLR7/8 agonist 13 has the potential to indirectly induce IFNγ, facilitating the response of HBV antigen-specific CD8 T cells. This compound is useful for hepatitis B virus research.Formula:C12H22N4O2Colore e forma:SolidPeso molecolare:254.33CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Formula:C21H17ClF3N3O3SColore e forma:SolidPeso molecolare:483.89HBV-IN-34
CAS:HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA
Formula:C21H19F2N7Purezza:98%Colore e forma:SolidPeso molecolare:407.42Ref: TM-T79469
Prodotto fuori produzioneYhhu6669
CAS:Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in
Formula:C29H28ClFN6O3Purezza:98%Colore e forma:SolidPeso molecolare:563.02Ref: TM-T78756
Prodotto fuori produzioneHBV-IN-38
CAS:HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].
Formula:C18H16F3N5O4S2Purezza:98%Colore e forma:SolidPeso molecolare:487.48
