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HBV

HBV

Gli inibitori dell'HBV sono composti progettati per colpire e inibire varie fasi del ciclo vitale del virus dell'epatite B (HBV). Questi inibitori possono interferire con la replicazione virale, l'assemblaggio o il rilascio, riducendo così la carica virale e contribuendo a gestire le infezioni croniche da HBV. La ricerca sugli inibitori dell'HBV è fondamentale per sviluppare terapie antivirali efficaci per prevenire malattie epatiche e cancro associati all'HBV. Presso CymitQuimica, offriamo una gamma di inibitori dell'HBV per supportare la vostra ricerca in virologia, sviluppo di farmaci antivirali e gestione delle malattie infettive.

Trovati 187 prodotti di "HBV"

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  • HBV-IN-41
    Targetmol
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    HBV-IN-41

    CAS:
    HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].
    Formula:C18H19ClFN5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:407.83

    Ref: TM-T79767

  • Carbovir
    Targetmol
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    Carbovir

    CAS:
    Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.
    Formula:C11H13N5O2
    Colore e forma:Solid
    Peso molecolare:247.25

    Ref: TM-T71241

  • Logo CymitQuimica
    Targetmol
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    Tobevibart

    CAS:
    Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].
    Purezza:98%
    Colore e forma:Liquid

    Ref: TM-T80970

  • HBV-IN-30
    Targetmol
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    HBV-IN-30

    CAS:
    HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.
    Formula:C22H18BrClO6
    Colore e forma:Solid
    Peso molecolare:493.73

    Ref: TM-T73281

  • Besifovir Dipivoxil maleate
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    Besifovir Dipivoxil maleate

    CAS:
    Besifovir Dipivoxil maleate, an oral HBV prodrug (LB80380), suppresses HBV DNA in naive and lamivudine-resistant CHB cases.
    Formula:C22H34N5O8P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:527.51

    Ref: TM-T13574

  • HBV-IN-8
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    HBV-IN-8

    CAS:
    HBV-IN-6 is a potent inhibitor of HBV (EC50: 287.9 nM).
    Formula:C21H25ClFN5O5S2
    Colore e forma:Solid
    Peso molecolare:546.04

    Ref: TM-T63852

  • Lagociclovir valactate
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    Lagociclovir valactate

    CAS:
    Lagociclovir valactate is a prodrug of Lagociclovir . Lagociclovir valactate is an orally active anti- HBV agent [1] .
    Formula:C18H25FN6O6
    Colore e forma:Solid
    Peso molecolare:440.43

    Ref: TM-T72324

  • Valtorcitabine dihydrochloride
    Targetmol
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    Valtorcitabine dihydrochloride

    CAS:
    Valtorcitabine dihydrochloride, a DNA polymerase inhibitor, is used potentially for the treatment of HBV infection.
    Formula:C14H24Cl2N4O5
    Colore e forma:Solid
    Peso molecolare:399.27

    Ref: TM-T29095

  • HBF-0259
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    HBF-0259

    CAS:
    HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.
    Formula:C16H12Cl2FN5
    Purezza:98.07% - 99.42%
    Colore e forma:Solid
    Peso molecolare:364.2

    Ref: TM-T27527

  • SHR5133
    Targetmol
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    SHR5133

    CAS:
    SHR5133 is a potent, orally active regulator of HBV capsid assembly that reduces HBV DNA (EC50: 26.6 nM).
    Formula:C19H18F4N6O2
    Colore e forma:Solid
    Peso molecolare:438.38

    Ref: TM-T62505

  • HEC72702
    Targetmol
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    HEC72702

    CAS:
    HEC72702: New HBV capsid inhibitor, from GLS4. No CYP1A2, CYP3A4, CYP2B6 induction at 10μM.
    Formula:C24H26BrFN4O5S
    Colore e forma:Solid
    Peso molecolare:581.45

    Ref: TM-T24135

  • HBV-IN-17
    Targetmol
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    HBV-IN-17

    CAS:
    <p>HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM).</p>
    Formula:C17H15F6N5O2
    Colore e forma:Solid
    Peso molecolare:435.32

    Ref: TM-T62466

  • Oxynitidine
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    Oxynitidine

    CAS:
    Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].
    Formula:C21H17NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:363.36

    Ref: TM-T80649

  • HBV-IN-13
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    HBV-IN-13

    CAS:
    HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).
    Formula:C22H25NO7
    Colore e forma:Solid
    Peso molecolare:415.44

    Ref: TM-T62144

  • IR415
    Targetmol
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    IR415

    CAS:
    IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx
    Formula:C13H14F2N4S
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:296.34

    Ref: TM-T11669

  • ent-Entecavir
    Targetmol
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    ent-Entecavir

    CAS:
    Ent-Entecavir, an enantiomeric impurity of Entecavir (an oral HBV drug), inhibits HBV replication as a reverse transcriptase inhibitor.
    Formula:C12H15N5O3
    Colore e forma:Solid
    Peso molecolare:277.28

    Ref: TM-T70092

  • AB-836
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    AB-836

    CAS:
    AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.
    Formula:C20H15F3N4O2
    Colore e forma:Solid
    Peso molecolare:400.35

    Ref: TM-T73492

  • Tenofovir amibufenamide
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    Tenofovir amibufenamide

    CAS:
    Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。
    Formula:C22H31N6O5P
    Purezza:99.19% - 99.87%
    Colore e forma:Solid
    Peso molecolare:490.49

    Ref: TM-T39043

  • Linvencorvir
    Targetmol
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    Linvencorvir

    CAS:
    <p>Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.</p>
    Formula:C29H35FN6O5S
    Purezza:99.9% - 99.9%
    Colore e forma:Solid
    Peso molecolare:598.69

    Ref: TM-T64221

  • ALG-000184
    Targetmol
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    ALG-000184

    CAS:
    <p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>
    Formula:C23H20FN4Na2O8P
    Colore e forma:Solid
    Peso molecolare:576.379

    Ref: TM-T204624

  • HBV/HDV-IN-2
    Targetmol
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    HBV/HDV-IN-2

    CAS:
    <p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>
    Formula:C38H44ClN7O5
    Colore e forma:Solid
    Peso molecolare:714.25

    Ref: TM-T88316

  • Logo CymitQuimica
    Targetmol
    + Info

    HBV-IN-20

    HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).
    Colore e forma:Solid

    Ref: TM-T64260

  • Logo CymitQuimica
    Targetmol
    + Info

    HBV-IN-18

    HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).
    Formula:C17H15F6N5O2
    Colore e forma:Solid
    Peso molecolare:435.32

    Ref: TM-T62467

  • HBV-IN-31
    Targetmol
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    HBV-IN-31

    CAS:
    HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.
    Formula:C23H18ClNO6
    Colore e forma:Solid
    Peso molecolare:439.85

    Ref: TM-T73282

  • HBV-IN-11
    Targetmol
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    HBV-IN-11

    CAS:
    HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).
    Formula:C21H24ClNO6
    Colore e forma:Solid
    Peso molecolare:421.87

    Ref: TM-T62256

  • HBV-IN-19 TFA
    Targetmol
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    HBV-IN-19 TFA

    CAS:
    HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.
    Formula:C26H31F3N2O8
    Colore e forma:Solid
    Peso molecolare:556.53

    Ref: TM-T63937

  • HBV-IN-12
    Targetmol
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    HBV-IN-12

    CAS:
    HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)
    Formula:C23H27NO8
    Colore e forma:Solid
    Peso molecolare:445.46

    Ref: TM-T62626

  • Logo CymitQuimica
    Targetmol
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    TLR8 agonist 4

    TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.
    Formula:C28H27N5O5S
    Colore e forma:Solid
    Peso molecolare:545.61

    Ref: TM-T63848

  • Logo CymitQuimica
    Targetmol
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    FNC-TP trisodium

    <p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>
    Formula:C9H11FN6Na3O13P3
    Colore e forma:Solid
    Peso molecolare:592.11

    Ref: TM-T64188

  • SAG-524
    Targetmol
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    SAG-524

    CAS:
    SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].
    Formula:C30H32ClN5O4S
    Colore e forma:Solid
    Peso molecolare:594.12

    Ref: TM-T87352

  • HBV-IN-48
    Targetmol
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    HBV-IN-48

    CAS:
    HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.
    Formula:C22H15F4N3O3
    Colore e forma:Solid
    Peso molecolare:445.37

    Ref: TM-T200299

  • Logo CymitQuimica
    Targetmol
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    HBV-IN-24

    HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.
    Formula:C23H27NO6
    Colore e forma:Solid
    Peso molecolare:413.46

    Ref: TM-T62115

  • CCC-0975
    Targetmol
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    CCC-0975

    CAS:
    CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.
    Formula:C21H17ClF3N3O3S
    Colore e forma:Solid
    Peso molecolare:483.89

    Ref: TM-T210630

  • HBV/HDV-IN-3
    Targetmol
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    HBV/HDV-IN-3

    CAS:
    <p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>
    Formula:C28H27BrF3N5O3
    Colore e forma:Solid
    Peso molecolare:618.44

    Ref: TM-T88050

  • HBV-IN-34
    Targetmol
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    HBV-IN-34

    CAS:
    <p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>
    Formula:C21H19F2N7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:407.42

    Ref: TM-T79469

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  • HBV-IN-38
    Targetmol
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    HBV-IN-38

    CAS:
    <p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>
    Formula:C18H16F3N5O4S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:487.48

    Ref: TM-T79879

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  • Yhhu6669
    Targetmol
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    Yhhu6669

    CAS:
    <p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>
    Formula:C29H28ClFN6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:563.02

    Ref: TM-T78756

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