gsk-3
Gli inibitori di GSK-3 sono composti che prendono di mira la Glicogeno Sintasi Chinasi 3 (GSK-3), un enzima coinvolto in numerosi processi cellulari, tra cui il metabolismo del glicogeno, la trascrizione genica e la proliferazione cellulare. GSK-3 è implicata in varie malattie, come il diabete, i disturbi neurodegenerativi e il cancro. Gli inibitori di GSK-3 sono strumenti importanti per esplorare queste vie e sviluppare potenziali terapie. Presso CymitQuimica, forniamo inibitori di GSK-3 per supportare la tua ricerca nelle malattie metaboliche, nella neurobiologia e nell'oncologia.
Trovati 110 prodotti per "gsk-3".
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9-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purezza:99.28% - 99.32%Colore e forma:SolidPeso molecolare:404.3474Indazole
CAS:Indazole, a heterocyclic compound, offers diverse biological activities.Formula:C7H6N2Purezza:99.59% - 99.85%Colore e forma:White SolidPeso molecolare:118.1359Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purezza:99.4% - 99.95%Colore e forma:White SolidPeso molecolare:512.33BRD0705
CAS:BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Formula:C20H23N3OPurezza:99.01%Colore e forma:SolidPeso molecolare:321.4161CHIR-98023
CAS:CHIR-98023 is a bio-active chemical.Formula:C20H16Cl2N8O2Colore e forma:SolidPeso molecolare:471.30PROTAC GSK-3β Degrader-1
PROTACGSK-3β Degrader-1 (compound 1) is a degrader targeting GSK-3β with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3β inhibitor), a PEG linker, and CRBN (E3 ligase ligand). It reduces neurotoxicity induced by Aβ25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.Formula:C43H42Cl2N6O9Colore e forma:SolidPeso molecolare:856.23903GSK3-IN-1
CAS:GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.Formula:C14H10ClN3OSPurezza:99.99%Colore e forma:SolidPeso molecolare:303.767GSK-3β inhibitor 21
GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.Colore e forma:Odour SolidPhospho-Glycogen Synthase Peptide-2(substrate)
CAS:Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Formula:C123H191N40O48PColore e forma:SolidPeso molecolare:3029.087GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formula:C15H12N4O2SColore e forma:SolidPeso molecolare:312.35MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purezza:99.64%Colore e forma:SolidPeso molecolare:370.2GSK-3 Inhibitor 5
CAS:4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.Formula:C9H6BrNOPurezza:99.9%Colore e forma:SolidPeso molecolare:224.054GSK3β/mTOR modulator 1
GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.Formula:C19H28O5Colore e forma:SolidPeso molecolare:336.19367FRATide
CAS:FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.Formula:C55H102N2O2Colore e forma:SolidPeso molecolare:823.433GSK-3β/HDAC-IN-2
GSK-3β/HDAC-IN-2 is a potent inhibitor of GSK-3β (IC50 = 0.04 μM), HDAC2 (IC50 = 1.05 μM, Ki = 0.070 μM), and HDAC6 (IC50 = 1.52 μM, Ki = 0.017 μM). It effectively inhibits HDAC2 and HDAC6 activities and prevents the hyperphosphorylation of tau protein. GSK-3β/HDAC-IN-2 demonstrates neuroprotective properties without significant toxicity and is useful for Alzheimer's disease research.Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Colore e forma:Odour SolidGSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Formula:C18H15N5O3Colore e forma:SolidPeso molecolare:349.352B-(SP)
CAS:Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)Formula:C71H123N26O29PPurezza:98%Colore e forma:SolidPeso molecolare:1835.87BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.Formula:C21H16N2O6Colore e forma:SolidPeso molecolare:392.36GSK-3β inhibitor 1
CAS:GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurezza:99.40%Colore e forma:SolidPeso molecolare:222.24
