gsk-3
Gli inibitori di GSK-3 sono composti che prendono di mira la Glicogeno Sintasi Chinasi 3 (GSK-3), un enzima coinvolto in numerosi processi cellulari, tra cui il metabolismo del glicogeno, la trascrizione genica e la proliferazione cellulare. GSK-3 è implicata in varie malattie, come il diabete, i disturbi neurodegenerativi e il cancro. Gli inibitori di GSK-3 sono strumenti importanti per esplorare queste vie e sviluppare potenziali terapie. Presso CymitQuimica, forniamo inibitori di GSK-3 per supportare la tua ricerca nelle malattie metaboliche, nella neurobiologia e nell'oncologia.
Trovati 111 prodotti di "gsk-3"
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GSK-3β inhibitor 10
CAS:GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.Formula:C12H12N2O3SPurezza:98.06%Colore e forma:SolidPeso molecolare:264.3GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurezza:98.86%Colore e forma:SolidPeso molecolare:337.36ALSTERPAULLONE
CAS:Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing EffecFormula:C16H11N3O3Purezza:99.8%Colore e forma:SolidPeso molecolare:293.28AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purezza:97.72% - 99.75%Colore e forma:SolidPeso molecolare:334.37BIO-acetoxime
CAS:<p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>Formula:C18H12BrN3O3Purezza:97.15%Colore e forma:SolidPeso molecolare:398.21CHIR-98014
CAS:<p>CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.</p>Formula:C20H17Cl2N9O2Purezza:97.25% - 99.59%Colore e forma:SolidPeso molecolare:486.31CHIR 98024
CAS:CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.Formula:C20H17Cl2N9O2Purezza:99.45%Colore e forma:SolidPeso molecolare:486.311-Azakenpaullone
CAS:1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.Formula:C15H10BrN3OPurezza:99.73%Colore e forma:Tan SolidPeso molecolare:328.16Aloisine B
CAS:<p>Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.</p>Formula:C15H14ClN3Purezza:95.15%Colore e forma:SolidPeso molecolare:271.74GSK3-IN-2
CAS:<p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>Formula:C17H19N3OSPurezza:98.8%Colore e forma:SolidPeso molecolare:313.42MRT80
CAS:MRT80 is an inhibitor of GSK-3 in vitro. MRT80 de-stabilizes MDM2 and stabilizes p53 protein and E2F-1.Formula:C15H15N5OPurezza:98%Colore e forma:SolidPeso molecolare:281.31TCS 2002
CAS:<p>GSK-3β inhibitor 9b: potent, selective, oral, IC50=35 nM, good pharmacokinetics, BBB-permeable, researched for Alzheimer's.</p>Formula:C18H14N2O3SColore e forma:SolidPeso molecolare:338.38ZDWX-25
CAS:ZDWX-25, a strong GSK-3β & DYRK1A inhibitor, kills SH-SY5Y/HL-7702 cells, may aid Alzheimer's research; IC50: 71 nM for GSK-3β.Formula:C17H15N3O3Colore e forma:SolidPeso molecolare:309.3218BIOder
CAS:18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.Formula:C9H7ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:210.62BRD3731
CAS:BRD3731 selectively inhibits GSK3β with IC50 of 15 nM; it's promising for PTSD, psychiatric issues, diabetes, and neurodegeneration.Formula:C24H31N3OColore e forma:SolidPeso molecolare:377.523F8
CAS:<p>3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in</p>Formula:C15H14N2O4Purezza:98.14% - 98.25%Colore e forma:SolidPeso molecolare:286.28VP3.15
CAS:VP3.15 is an orally bioavailable and CNS-penetrant dual inhibitor of phosphodiesterase (PDE)7- GSK3 (IC50s: 1.59 μM and 0.88 μM for PDE7 and GSK-3).Formula:C20H22N4OSPurezza:98%Colore e forma:SolidPeso molecolare:366.48Cazpaullone
CAS:Cazpaullone inhibits GSK-3 and briefly boosts Pax4 mRNA expression.Formula:C16H10N4OColore e forma:SolidPeso molecolare:274.28TC-G 24
CAS:GSK-3β inhibitorFormula:C15H11ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:330.73BRD1652
CAS:BRD1652 is a highly selective and potent GSK3 inhibitor.Formula:C20H20F3N3OPurezza:98%Colore e forma:SolidPeso molecolare:375.39
