AMPK
Gli inibitori di AMPK sono composti che inibiscono la Proteina Chinasi Attivata da AMP (AMPK), un enzima che svolge un ruolo critico nell'omeostasi energetica cellulare. AMPK si attiva in risposta a bassi livelli di energia nelle cellule e aiuta a regolare processi come l'assorbimento del glucosio, l'ossidazione degli acidi grassi e la biogenesi mitocondriale. Inibire AMPK è importante per studiare il suo ruolo nelle malattie metaboliche, nel cancro e nell'invecchiamento. Presso CymitQuimica, offriamo una gamma di inibitori di AMPK per supportare la tua ricerca in metabolismo, oncologia e malattie legate all'età.
Trovati 171 prodotti di "AMPK"
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Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formula:C23H30O7Colore e forma:SolidPeso molecolare:418.486TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Formula:C21H32O6Purezza:99.21%Colore e forma:SolidPeso molecolare:380.48Ref: TM-T13173
1mg80,00€5mg167,00€10mg274,00€25mg465,00€50mg655,00€100mg1.017,00€1mL*10mM (DMSO)170,00€AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Formula:C23H24BrNO2Purezza:99.55%Colore e forma:SolidPeso molecolare:426.35ML753286
CAS:ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formula:C20H25N3O3Purezza:98%Colore e forma:SolidPeso molecolare:355.43ULK1-IN-2
CAS:ULK1-IN-2, a potent anticancer agent, inhibits ULK1, induces apoptosis, blocks autophagy, and shows high cytotoxicity with an IC50 of 1.94 μM in A549 cells.Formula:C19H16BrFN4O6Purezza:99.07% - 99.97%Colore e forma:SolidPeso molecolare:495.26JJO-1
CAS:JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formula:C19H13N3Colore e forma:SolidPeso molecolare:283.33AMPK activator
CAS:AMPK activatorFormula:C22H21FO4Purezza:98%Colore e forma:SolidPeso molecolare:368.4AMPK activator 8
CAS:AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.Formula:C25H21ClN2O6Colore e forma:SolidPeso molecolare:480.9PF-07899895
CAS:PF-07899895 is an inhibitor of SIK. The IC50 values for SIK1, SIK2 and SIK3 are 1.2 nM, 0.9 nM and 1.8 nM respectively.Formula:C23H23N5OSPeso molecolare:417.53Ref: TM-T200199
1mg464,00€5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiestaSMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurezza:98%Colore e forma:SolidPeso molecolare:718.02IND 1316
CAS:IND 1316 is an activator of AMP-activated protein kinase (AMPK).Formula:C22H17NO3Colore e forma:SolidPeso molecolare:343.38AMDE-1
CAS:<p>AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.</p>Formula:C18H8ClF6N3Purezza:90%Colore e forma:SolidPeso molecolare:415.72OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Formula:C25H24F3N3O6S2Colore e forma:SolidPeso molecolare:583.6AMPK activator 4
CAS:Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.Formula:C24H21ClN2O3Purezza:99.97% - 99.99%Colore e forma:SolidPeso molecolare:420.89Ref: TM-T62238
1mg90,00€5mg183,00€10mg354,00€25mg595,00€50mg847,00€100mg1.159,00€500mg2.308,00€1mL*10mM (DMSO)215,00€AMPK activator 1
CAS:AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Formula:C32H33F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:578.62GL-V9
CAS:GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.Formula:C24H27NO5Colore e forma:SolidPeso molecolare:409.47Galegine hydrochloride
CAS:Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.Formula:C6H14ClN3Colore e forma:SolidPeso molecolare:163.65HL271
CAS:HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Formula:C13H17ClF3N5OPurezza:98%Colore e forma:SolidPeso molecolare:351.76LRRK2/NUAK1/TYK2-IN-1
CAS:LRRK2/NUAK1/TYK2-IN-1 inhibits LRRK2, TYK2, NUAK1 with IC50 < 10 nM, useful in autoimmune research.Formula:C20H11F3N6Colore e forma:SolidPeso molecolare:392.34MARK-IN-4
CAS:MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.Formula:C21H23N7OSColore e forma:SolidPeso molecolare:421.52
