AMPK
Gli inibitori di AMPK sono composti che inibiscono la Proteina Chinasi Attivata da AMP (AMPK), un enzima che svolge un ruolo critico nell'omeostasi energetica cellulare. AMPK si attiva in risposta a bassi livelli di energia nelle cellule e aiuta a regolare processi come l'assorbimento del glucosio, l'ossidazione degli acidi grassi e la biogenesi mitocondriale. Inibire AMPK è importante per studiare il suo ruolo nelle malattie metaboliche, nel cancro e nell'invecchiamento. Presso CymitQuimica, offriamo una gamma di inibitori di AMPK per supportare la tua ricerca in metabolismo, oncologia e malattie legate all'età.
Trovati 168 prodotti di "AMPK"
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AMPK activator 6
CAS:<p>AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.</p>Formula:C25H28O5Colore e forma:SolidPeso molecolare:408.49XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Formula:C21H24N8OPurezza:99.04%Colore e forma:SoildPeso molecolare:404.47PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Formula:C23H23ClN2O5Purezza:98%Colore e forma:SolidPeso molecolare:442.89YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Formula:C21H21FN2OPurezza:98%Colore e forma:SolidPeso molecolare:336.4DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurezza:99.63%Colore e forma:SolidPeso molecolare:407.7YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Formula:C29H20ClNO3Purezza:97.74%Colore e forma:SolidPeso molecolare:465.93PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Formula:C17H16ClN3O3Purezza:97.01%Colore e forma:SolidPeso molecolare:345.78MRT199665
CAS:MRT199665, a selective MARK/SIK/AMPK inhibitor, blocks SIK CRTC3 S370 phosphorylation and triggers apoptosis in AML cells.Formula:C28H31N5O2Colore e forma:SolidPeso molecolare:469.58Butylate
CAS:Butylate is a herbicide of thiocarbamate.Formula:C11H23NOSColore e forma:Less Liquid Which Darkens Upon Exposure To Light Air And Moisture Colorless Liquid Which Darkens Upon Exposure To Light Air And MoisturePeso molecolare:217.37ZLN024
CAS:<p>ZLN024 is an activator of AMPK allosteric.</p>Formula:C13H13BrN2OSPurezza:99.751%Colore e forma:SolidPeso molecolare:325.22MARK-IN-1
CAS:MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor, (IC50<0.25 nM).Formula:C22H23F2N7OSPurezza:98%Colore e forma:SolidPeso molecolare:471.53AMPK-α1β1γ1 activator 1
CAS:AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1Formula:C25H24ClNO9Purezza:98%Colore e forma:SolidPeso molecolare:517.91Demethyleneberberine chloride
CAS:Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-Formula:C19H18ClNO4Purezza:98%Colore e forma:SolidPeso molecolare:359.8Ampkinone
CAS:Ampkinone is an indirect AMPK activator.Formula:C31H23NO6Purezza:98%Colore e forma:SolidPeso molecolare:505.52MARK-IN-2
CAS:MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor,(IC50:5 nM).Formula:C18H18ClF2N5OSPurezza:98%Colore e forma:SolidPeso molecolare:425.88PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Formula:C20H17F2NO3Purezza:98%Colore e forma:SolidPeso molecolare:357.35AMPK-IN-1
CAS:AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM.Formula:C24H18ClN3O3Colore e forma:SolidPeso molecolare:431.8710Z-Hymenialdisine
CAS:Pan kinase inhibitorFormula:C11H10BrN5O2Purezza:98%Colore e forma:Light Yellow SolidPeso molecolare:324.13MK-0626
CAS:MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor enhancing AMP, restoring the expression of GLP-1R. promoting neoangiogenesis.Formula:C22H24F2N6O2Purezza:99.47% - >99.99%Colore e forma:SolidPeso molecolare:442.46AMPK activator 7
CAS:<p>AMPK activator 7 (I-3-24, EC50: 8.8 nM) targets AMPK-related disorders like type 2 diabetes and obesity.</p>Formula:C23H22F3N3O5Colore e forma:SolidPeso molecolare:477.43
