PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 231 prodotti di "PI3K"
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CAL-130
CAS:CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurezza:98%Colore e forma:SolidPeso molecolare:426.47PI3K-IN-38
CAS:PI3K-IN-38: oral PI3K inhibitor, IC50 of 0.541 µM, anticancer, anti-inflammatory, halts tumors in vivo.Formula:C20H24N6O2Purezza:99.89%Colore e forma:SolidPeso molecolare:380.44PI3K-IN-9
CAS:PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).Formula:C19H23N7OPurezza:98%Colore e forma:SolidPeso molecolare:365.43PQR514
CAS:PQR514: more potent pan-PI3K inhibitor than predecessor PQR309, exhibits strong anticancer activity in vitro and in OVCAR-3 model.
Formula:C16H20F2N8O2Purezza:98.77% - 99.19%Colore e forma:SolidPeso molecolare:394.38TGX-115
CAS:TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) & p110δ (IC50=0.63μM), treats various cardiovascular diseases.Formula:C20H20N2O3Purezza:99.48%Colore e forma:SolidPeso molecolare:336.38Ref: TM-T24873
1mg200,00€5mg472,00€10mg645,00€25mg905,00€50mg1.121,00€100mg1.425,00€200mg1.863,00€1mL*10mM (DMSO)389,00€NVP-BAG956
CAS:NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).Formula:C28H21N5Purezza:99.25% - 99.80%Colore e forma:SolidPeso molecolare:427.5Ref: TM-TQ0313
1mg57,00€5mg120,00€10mg210,00€25mg424,00€50mg707,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)133,00€AZ044
CAS:AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).Formula:C24H27N3O3SPurezza:99.5%Colore e forma:SolidPeso molecolare:437.55Ref: TM-T26698
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€200mg1.558,00€1mL*10mM (DMSO)126,00€SRX3207
CAS:SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.Formula:C29H29N7O3SPurezza:99.85%Colore e forma:SolidPeso molecolare:555.65GS-9901
CAS:GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.Formula:C22H17ClFN9OPurezza:98.60% - 99.92%Colore e forma:SolidPeso molecolare:477.88NVP-QAV-572
CAS:NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).Formula:C17H19F2N7O3S2Purezza:98%Colore e forma:SolidPeso molecolare:471.5MSC2360844
CAS:MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).Formula:C26H27FN4O5SPurezza:99.54% - 99.9%Colore e forma:SolidPeso molecolare:526.58Ref: TM-T12115
1mg52,00€5mg116,00€10mg182,00€25mg354,00€50mg568,00€100mg900,00€200mg1.206,00€1mL*10mM (DMSO)135,00€LAS191954
CAS:LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).Formula:C20H15N9OPurezza:98%Colore e forma:SolidPeso molecolare:397.39CAL-130 Racemate
CAS:CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurezza:98%Colore e forma:SolidPeso molecolare:426.47GNE-490
CAS:GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively.Formula:C18H22N6O2SPurezza:99.77%Colore e forma:SolidPeso molecolare:386.47Ref: TM-T22339
1mg85,00€2mg115,00€5mg188,00€10mg321,00€25mg509,00€50mg702,00€100mg932,00€200mg1.283,00€1mL*10mM (DMSO)205,00€PI3Kδ-IN-17
CAS:PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing theFormula:C23H24F3N7O2Purezza:98%Colore e forma:SolidPeso molecolare:487.48Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Formula:C42H70O12Purezza:98.46% - 99.13%Colore e forma:SolidPeso molecolare:767.00PIK-inhibitors
CAS:PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.Formula:C19H17N5O2Purezza:96.98%Colore e forma:SolidPeso molecolare:347.37SAR-260301
CAS:SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM).Formula:C19H22N4O3Purezza:99.74%Colore e forma:SolidPeso molecolare:354.4Ref: TM-T16841
2mg43,00€5mg65,00€10mg87,00€25mg173,00€50mg264,00€100mg371,00€200mg523,00€1mL*10mM (DMSO)71,00€Zandelisib
CAS:Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.Formula:C31H38F2N8OPurezza:99.88%Colore e forma:SolidPeso molecolare:576.68Ref: TM-T13386
1mg85,00€5mg177,00€10mg279,00€25mg487,00€50mg655,00€100mg900,00€1mL*10mM (DMSO)225,00€PI3Kδ-IN-1
CAS:PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).Formula:C22H20F3N7O2Purezza:99.85%Colore e forma:SolidPeso molecolare:471.44
