PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 231 prodotti di "PI3K"
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YS-49
CAS:YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).Formula:C20H20BrNO2Purezza:99.65%Colore e forma:SolidPeso molecolare:386.28Ref: TM-T13376
1mg46,00€2mg58,00€5mg95,00€10mg137,00€25mg260,00€50mg386,00€100mg560,00€500mg1.153,00€1mL*10mM (DMSO)92,00€LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purezza:98% - 99.96%Colore e forma:Pale Yellow SolidPeso molecolare:307.34Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purezza:99.66% - 99.74%Colore e forma:SolidPeso molecolare:696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€1mL*10mM (DMSO)107,00€TGX-221
CAS:TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.Formula:C21H24N4O2Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:364.44LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurezza:99.45%Colore e forma:SolidPeso molecolare:474.91Ref: TM-T4398
2mg34,00€5mg50,00€10mg79,00€25mg130,00€50mg216,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)55,00€PI-3065
CAS:PI-3065 is a novel potent and selective PI3K p110δ inhibitor.Formula:C27H31FN6OSPurezza:99.84% - ≥95%Colore e forma:SolidPeso molecolare:506.64CZC24832
CAS:CZC24832 is a selective inhibitor of PI 3-kinase γ.Formula:C15H17FN6O2SPurezza:99.08% - 99.12%Colore e forma:SolidPeso molecolare:364.4Ref: TM-T1949
1mg48,00€2mg63,00€5mg92,00€10mg138,00€25mg226,00€50mg338,00€100mg497,00€1mL*10mM (DMSO)104,00€Fimepinostat
CAS:Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formula:C23H24N8O4SPurezza:98.27% - 99.87%Colore e forma:SolidPeso molecolare:508.55Ref: TM-T2078
2mg44,00€5mg66,00€10mg92,00€25mg172,00€50mg295,00€100mg485,00€500mg1.035,00€1mL*10mM (DMSO)74,00€TASP0415914
CAS:TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormula:C13H17N5O3SPurezza:98.14%Colore e forma:SolidPeso molecolare:323.37Ref: TM-T7879
1mg52,00€5mg111,00€10mg177,00€25mg299,00€50mg424,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)127,00€PIK-108
CAS:PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).Formula:C22H24N2O3Purezza:98.92%Colore e forma:SolidPeso molecolare:364.44Ref: TM-T28416
1mg40,00€2mg57,00€5mg97,00€10mg156,00€25mg255,00€50mg368,00€100mg510,00€200mg700,00€1mL*10mM (DMSO)105,00€Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purezza:98.63% - 99.54%Colore e forma:SolidPeso molecolare:450.39Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurezza:99.79% - 99.93%Colore e forma:SolidPeso molecolare:505.69ETP-46321
CAS:ETP-46321 is an effective and orally bioavailable PI3Kα/PI3Kδ inhibitor (Ki: 2.3/14.2 nM).Formula:C20H27N9O3SPurezza:99.8%Colore e forma:SolidPeso molecolare:473.55Ref: TM-TQ0229
1mg37,00€5mg82,00€10mg116,00€25mg212,00€50mg298,00€100mg408,00€200mg552,00€1mL*10mM (DMSO)86,00€Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormula:C14H11ClN6O3Purezza:99.25% - 99.41%Colore e forma:SolidPeso molecolare:346.73Ref: TM-T4219
2mg39,00€5mg58,00€10mg88,00€25mg160,00€50mg215,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)66,00€Taselisib
CAS:Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.Formula:C24H28N8O2Purezza:99.62% - 99.79%Colore e forma:SolidPeso molecolare:460.53Ref: TM-T1999
2mg46,00€5mg66,00€10mg92,00€25mg157,00€50mg197,00€100mg350,00€200mg522,00€500mg840,00€1mL*10mM (DMSO)66,00€IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formula:C26H23FN8OPurezza:99.31%Colore e forma:SolidPeso molecolare:482.51Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purezza:98.92%Colore e forma:SolidPeso molecolare:338.35Leniolisib
CAS:Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).
Formula:C21H25F3N6O2Purezza:99.88%Colore e forma:SolidPeso molecolare:450.46Brevianamide F
CAS:Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.
Formula:C16H17N3O2Purezza:97.30% - 98.82%Colore e forma:SolidPeso molecolare:283.33Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purezza:96.66% - 99.93%Colore e forma:SolidPeso molecolare:332.39
