Composti policiclici

<p>Applications 3,5-Dichloro-4-pyridone-1-acetic acid<br></p>

<p>Applications 1-(4-Chlorobutyl)-7-hydroxyquinolin-2(1H)-one is a useful research chemical.<br></p>

<p>Applications Quinoline derivative as antibacterial agents.<br>References O'Neill, P., et al.: Pharmacol. Ther., 77, 29 (1998), Dorn, C., et al.: Bioorg. Med. Chem. Lett., 11, 259 (2001), Scozzafava, A., et al.: Curr. Med. Chem., 10, 925 (2003),<br></p>

<p>Applications 2-(prop-2-yn-1-yl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 410538-30-6) is a useful research chemical.<br></p>

<p>Applications 2-Chloroquinolin-6-ol can be used for hair dye compositions.<br>References Lagrange, A., et.al., PCT Int. Appl., 87, (2012);<br></p>

<p>Applications 4,7-difluoro-1H-indole-2-carboxylic acid (cas# 247564-67-6) is a useful research chemical.<br></p>

<p>Applications An intermediate in the preparation of Azasetron.<br>References Baker, S., et al.: Bioorg. Med. Chem. Lett., 15, 4727 (2005), Odzak, R., et al.: Bioorg. Chem., 34, 90 (2006), Anand, R., et al.: J. Med. Chem., 52, 1602 (2009),<br></p>

<p>Applications Isotope labelled 6-Bromopurine is a brominated derivative of purine used in various organic syntheses. Used in the synthesis of several benzo-fused scaffolds with purine or pyrimidine moietes which display antitumor and anticancer properties.<br>References Morales, F. et al.: Eur, J. Med. Chem., 76, 118 (2014); Cushing, T. et al.: J. Med. Chem., 58, 480 (2015); Jansen, R., et al.: Clin. Biochem., 38, 362 (2005),<br></p>

<p>Applications 7-Phenoxyquinolin-2(1H)-one is a useful research chemical.<br></p>

<p>Applications 2-Benzyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid (cas# 54329-48-5) is a useful research chemical.<br></p>

<p>Applications Methyl-2-aminoquinoline-6-carboxylate is an organic building block of ester and amine category.<br>References Li, L., et al.: PCT Int. Appl. (2018), WO 2018196823 A1 20181101<br></p>

<p>Applications 3-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)propanoic Acid (cas# 923163-76-2) is a useful research chemical.<br></p>

<p>Applications 5-Fluoro-2-oxindole (cas# 56341-41-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 9,9-Dimethyl-xanthene-3,6-diol has been used in the manufacturing of dihydroxydiaminoxanthenes as monomers for positive-working resists by treatment of dihydroxybenzenes with carbonyl compounds, nitration, and reduction.<br>References Sumitani, N.; et al.: Jpn. Kokai Tokkyo Koho 13 pp. Patent 2004 CODEN:JKXXAF<br></p>

<p>Applications 8-Hydroxyquinoline Copper Salt is used in the formulation of biocide microcapsules towards stabilized iodine-​containing compounds for protection of technical materials from degradation by microorganisms.<br>References Boettcher, A., et al.: PCT Int. Appl. (2012), WO 2012076699 A1 20120614<br></p>

<p>Applications 8-aza-9-boratricyclo[8.4.0.0,2,7]tetradeca-1(14),2,4,6,10,12-hexaen-9-ol (cas# 17012-25-8) is a useful research chemical.<br></p>

<p>Applications methyl 8,8-dioxo-8lambda6-thia-2,3,5,7-tetraazatricyclo[7.4.0.0,2,6]trideca-1(13),3,5,9,11-pentaene-4-carboxylate (cas# 1311315-62-4) is a useful research chemical.<br></p>

<p>Applications octahydro-1H-indole-2-carboxamide (cas# 1105694-34-5) is a useful research chemical.<br></p>

<p>Applications 4-(1-Piperazinyl)-1H-indole Dihydrochloride (cas# 84807-09-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Isoquinolin-4-yl-benzylamine is an analog of amino isoquinolin (A611600). Amino isoquinolin ( A611600) is used for synthesis of Rho kinase inhibitors.<br>References Kimura, K; Science, 273, 245 (1996);Amano, M; J Biol Chem 274, 32418 (1999)Gassel, M; J Mol Biol, 329, 1021 (2003);<br></p>

<p>Applications Quinoline-4-carboxylic acid (cas# 486-74-8) is a useful research chemical.<br></p>

<p>Applications 3-Isocyanato-1H-indole (cas# 57778-78-6) is a useful research chemical.<br></p>

<p>Applications 6-hydroxyquinoline-2-carboxylic acid (cas# 75434-18-3) is a useful research chemical.<br></p>

<p>Applications 1-(2-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline (cas# 1017125-85-7) is a useful research chemical.<br></p>

<p>Applications 6-[N,N-Di(2-hydroxybenzyl)amino]-2-[(3-hydroxypropyl)amino]-9-isopropylpurine (cas# 1076200-04-8) is a compound useful in organic synthesis.<br></p>

<p>Applications (1R,​4S)​-1,​3,​3-​Trimethylbicyclo[2.2.1]​heptan-​2-​one also known more commonly as (-)-Fenchone is a chiral intermediate of Fenchone and is currently being used for studies ranging from inhibitory effects of monoterpenes on human TRPA1 and odorant receptor of the malaria vector Anopheles gambiae.<br>References Rahman, S., et al. J. Biol. Chem., 292, 18916-23 (2017); Takaishi, M., et al.: J Physio. Sci., 64, 47-57 (2014)<br></p>

<p>Applications 2,6-Dimethylphenanthrene have been used in investigating Polycyclic Aromatic Hydrocarbons Profiles in Higher Plants Using Statistical Models.<br>References Sojinu O., et al.: Int. J. Phytoremediat., 15, 439-451 (2013)<br></p>

<p>Applications 2-tert-Butyl-1H-indole (cas# 1805-65-8) is a useful research chemical.<br></p>

<p>Applications 6-Bromo-2-(4-bromophenyl)indole (cas# 28718-96-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-Diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct (cas# 119752-83-9) is a useful research chemical.<br></p>

<p>Applications 5,7-dihydroxy-4-methyl-2H-chromen-2-one (cas# 2107-76-8) is a useful research chemical.<br></p>

<p>Applications Indole derivative, as antiviral and antitumor agent.<br>References Borza, I., et al.: J. Med. Chem., 50, 901 (2007), Lefoix, M., et al.: Bioorg. Med. Chem., 16, 5303 (2008), Frost, J., et al.: J. Med. Chem., 51, 1904 (2008),<br></p>

<p>Applications XANTHENE-9-CARBOXAMIDE (cas# 5813-90-1) is a useful research chemical.<br></p>

<p>Applications 1,2,3,4-Tetrahydroisoquinoline-6,7-diol hydrobromide (cas# 52768-23-7) is a useful research chemical.<br></p>

<p>Applications 6-fluoroquinoline-8-carboxylic acid (cas# 1306605-84-4) is a useful research chemical.<br></p>

<p>Applications (Z)-9-(2-Propen-1-ylidene)-2-(trifluoromethyl)-9H-thioxanthene is an intermediate used in the synthesis of (E/Z)-Flupentixol-d4 Dihydrochloride (F597982), which is a neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.<br>References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),<br></p>

<p>Applications 2-(pyridin-3-yl)pyrido[2,3-d]pyrimidine has been used in the preparation of divalent transition metal aminonicotinaldehyde chloride complexes, antimicrobial, antioxidant and antitumor activities, electrochemical and molecular docking with EGFR protein.<br>References Konakanchi R., et al., Res. Chem. Intermed., 44, 27-53 (2018)<br></p>

<p>Applications 2,3,3-Trimethylindolenine is an indole derivative used in the preparation of cyanine dye labelleing reagents and other imaging agents.<br>References Mujumdar, R. et al.: Cytometry, 10, 3 (1989); Mushkalko, I.L. et al.: Ukr. Khim. Zhur., 52, 509 (1986);<br></p>

<p>Applications 4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 5488-36-8) is a useful research chemical.<br></p>

<p>Applications 5,7-Diazaspiro[3.4]Octane-6,8-Dione (cas# 89691-88-3) is a useful research chemical.<br></p>

<p>Applications 3-(ETHOXYCARBONYL)BICYCLO[1.1.1]PENTANE-1-CARBOXYLIC ACID (cas# 1823373-90-5) is a useful research chemical.<br></p>

<p>Applications 2-Azabicyclo[2.2.2]octan-3-one (cas# 3306-69-2) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.<br>References Fu, Y., Zhongguo Xinyao Zazhi, 22, 26 (2013); Liu, M., Adv. Mat. Res., 396, 1490 (2012); Camp, R., et al.: Cancer, 86, 2259 (1999);<br></p>

<p>Applications 7-Chloro-3-isoquinolinemethanol is an intermediate in the preparation of pyrrolopyrimidinones as P2X3 receptor antagonists.<br>References Bayrakdarian, M., et al.: PCT Int. Appl. (2008), WO 2008136756 A1 20081113;<br></p>

<p>Stability Hygroscopic<br>Applications 2-AMINO-1,2,3,4-TETRAHYDROISOQUINOLINE-1,3-DIONE (cas# 22177-46-4) is a useful research chemical.<br></p>

<p>Applications N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is used in synthesis of an antitumor agent, neratinib (N390090).<br>References Zhang, P., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 355 (2008);<br></p>

<p>Applications 2,2'-Bipyridine-4,4'-dicarboxamide<br></p>