Segnalazione citoscheletrica
Gli inibitori della segnalazione del citoscheletro sono composti che interrompono le vie di segnalazione che regolano il citoscheletro, cruciale per la forma, la motilità, la divisione delle cellule e il trasporto intracellulare. Questi inibitori vengono utilizzati per studiare la dinamica delle proteine del citoscheletro, come actina e tubulina, e il loro ruolo in processi come la migrazione cellulare, l'adesione e la metastasi del cancro. Gli inibitori della segnalazione del citoscheletro sono preziosi nella ricerca sulla biologia cellulare, sul cancro e sulla neurobiologia. Presso CymitQuimica, offriamo una gamma completa di inibitori della segnalazione del citoscheletro di alta qualità per supportare le tue ricerche in questi ambiti.
Trovati 1530 prodotti di "Segnalazione citoscheletrica"
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Spiperone
CAS:Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Formula:C23H26FN3O2Purezza:99.34% - 99.91%Colore e forma:SolidPeso molecolare:395.47Fluorofenidone
CAS:<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Formula:C12H10FNOPurezza:99.85%Colore e forma:SolidPeso molecolare:203.21AC 7739
CAS:<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Formula:C18H22ClNO4Purezza:99.38% - 99.55%Colore e forma:SoildPeso molecolare:351.83DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Formula:C38H54ClN3O10SPurezza:98.15%Colore e forma:SolidPeso molecolare:780.37Tadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Purezza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:47.59 kDaAS1949490
CAS:AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Formula:C20H18ClNO2SPurezza:99.94%Colore e forma:SolidPeso molecolare:371.88Ref: TM-T14327
1mg40,00€2mg52,00€5mg88,00€10mg126,00€25mg250,00€50mg401,00€100mg585,00€1mL*10mM (DMSO)87,00€7-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurezza:91.05%Colore e forma:White Solid PowderPeso molecolare:272.28Elarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purezza:99.08%Colore e forma:SoildPeso molecolare:644.56(+)-Blebbistatin
CAS:<p>(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.</p>Formula:C18H16N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:292.33Danicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formula:C16H20F3N5O4SPurezza:99.38%Colore e forma:SolidPeso molecolare:435.42Ref: TM-T15050
1mg136,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€1mL*10mM (DMSO)303,00€Veltuzumab
CAS:Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.Purezza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.33 kDaDasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:506.03TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purezza:99.4%Colore e forma:SoildPeso molecolare:416.47Ref: TM-T77660
1mg42,00€2mg52,00€5mg87,00€10mg127,00€25mg250,00€50mg373,00€100mg547,00€500mg1.159,00€Nilotinib
CAS:<p>Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.</p>Formula:C28H22F3N7OPurezza:99.89% - >99.99%Colore e forma:Off-White SolidPeso molecolare:529.52Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurezza:99.05%Colore e forma:SolidPeso molecolare:367.85Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formula:C26H26N4O4Purezza:99.27%Colore e forma:SolidPeso molecolare:458.51Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Purezza:>95%Colore e forma:LiquidVedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Purezza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Colore e forma:LiquidPeso molecolare:146.80 kDaAbrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purezza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidCibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purezza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Colore e forma:LiquidPeso molecolare:191.1 kDaTeplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purezza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Colore e forma:LiquidPeso molecolare:145.79 kDaVerubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurezza:98.29% - 99.77%Colore e forma:SolidPeso molecolare:315.8Ref: TM-T13298
5mg50,00€10mg78,00€25mg145,00€50mg210,00€100mg300,00€200mg434,00€1mL*10mM (DMSO)56,00€ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurezza:98% - 99.98%Colore e forma:SolidPeso molecolare:711.67Imatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Formula:C29H31N7O·CH4SO3Purezza:98% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:589.71Adropin (34-76) (human, mouse, rat)
CAS:Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Formula:C190H293N55O68S2Purezza:94.23% - 99.95%Colore e forma:SolidPeso molecolare:4499.82RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurezza:99.09%Colore e forma:SolidPeso molecolare:410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€IMAB027
CAS:<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Purezza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Colore e forma:LiquidSGC-AAK1-1
CAS:<p>SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.</p>Formula:C21H25N5O3SPurezza:99.68%Colore e forma:SolidPeso molecolare:427.52CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurezza:99.01% - 99.04%Colore e forma:SolidPeso molecolare:466.46Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purezza:98.40%Colore e forma:SolidPeso molecolare:439.89Tidutamab
CAS:Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).Purezza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Colore e forma:LiquidOrbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purezza:97.21% - 98.72%Colore e forma:SolidPeso molecolare:475.42Donanemab
CAS:Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Purezza:95%Colore e forma:LiquidGNE 2861
CAS:GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Formula:C22H26N6O2Purezza:97.03%Colore e forma:SolidPeso molecolare:406.48Ref: TM-T16429
1mg43,00€2mg55,00€5mg87,00€10mg131,00€25mg259,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)92,00€Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formula:C14H11NO4Purezza:99.03% - 99.96%Colore e forma:SolidPeso molecolare:257.24Ref: TM-T10860
2mg47,00€5mg70,00€10mg107,00€25mg216,00€50mg350,00€100mg542,00€200mg778,00€500mg1.169,00€1mL*10mM (DMSO)70,00€Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purezza:99.44% - 99.98%Colore e forma:SolidPeso molecolare:429.85GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formula:C17H18N4O2SPurezza:99.49%Colore e forma:SoildPeso molecolare:342.42Xentuzumab
CAS:Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Purezza:95.21% - >95.0% (SDS-PAGE); >95.0% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:143.7 kDaPKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purezza:95.42%Colore e forma:SoildMosunetuzumab
CAS:Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.Purezza:SDS-PAGE:94.4%;SEC-HPLC:96.1%Colore e forma:LiquidPeso molecolare:146.27 kDaBosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purezza:98.98% - 99.9%Colore e forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecolare:530.45IPI-493
CAS:IPI-493 is a bioactive chemical.Formula:C28H39N3O8Purezza:>99.99%Colore e forma:SolidPeso molecolare:545.62Lyn-IN-1
CAS:Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFormula:C30H31F3N8OPurezza:97% - 98.02%Colore e forma:SolidPeso molecolare:576.62Ref: TM-T11916
1mg40,00€2mg52,00€5mg84,00€10mg124,00€25mg250,00€50mg393,00€100mg560,00€200mg812,00€1mL*10mM (DMSO)97,00€Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:144.22 kDa2,3-Butanedione 2-Monoxime
CAS:2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.Formula:C4H7NO2Purezza:98.62%Colore e forma:Physical Description Cream-Colored Powder (Ntp 1992)Peso molecolare:101.1ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formula:C15H18Cl2N2O2SPurezza:99.69%Colore e forma:Crystalline SolidPeso molecolare:361.29Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formula:C22H26ClN7O2SPurezza:99.59% - 99.86%Colore e forma:Pale-Yellow SolidPeso molecolare:488.01Larazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formula:C34H59N9O12Purezza:95.53% - 99.425%Colore e forma:SolidPeso molecolare:785.89Delcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formula:C120H199N45O34S2Purezza:99.96%Colore e forma:SolidPeso molecolare:2880.28Ref: TM-T11740
1mg202,00€5mg512,00€10mg740,00€25mg1.121,00€50mg1.539,00€100mg2.072,00€1mL*10mM (DMSO)1.691,00€Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purezza:> 95% - >95.0% (SDS-PAGE)Colore e forma:LiquidPeso molecolare:145.3 kDaTalquetamab
CAS:Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Colore e forma:LiquidPeso molecolare:144.59 kDaGlofitamab
CAS:<p>Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.</p>Purezza:SDS-PAGE:98.2%;SEC-HPLC:98.0%Colore e forma:LiquidPeso molecolare:170.37 kDaA-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formula:C12H14Cl2N2O2SPurezza:99.32%Colore e forma:SolidPeso molecolare:321.22ADH-1 trifluoroacetate
CAS:ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Formula:C24H35F3N8O8S2Purezza:90.08% - 99.98%Colore e forma:SolidPeso molecolare:684.71Ref: TM-T1608
2mg44,00€5mg65,00€10mg95,00€25mg170,00€50mg240,00€100mg358,00€200mg509,00€1mL*10mM (DMSO)95,00€Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purezza:SDS-PAGE:95% SEC-HPLC:98.77%Colore e forma:LiquidPeso molecolare:146.14 kDaAbciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purezza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Colore e forma:LiquidPeso molecolare:95.18 kDaCC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formula:C22H20ClN5O3SPurezza:99.59%Colore e forma:SolidPeso molecolare:469.94Pamidronate Disodium
CAS:Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Formula:C3H9NNa2O7P2Purezza:99.86% - 99.93%Colore e forma:White CrystalsPeso molecolare:279.03Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formula:C17H31N7O10Purezza:98.14%Colore e forma:SolidPeso molecolare:493.47LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formula:C25H25F3N4O4Purezza:98.3% - 99.92%Colore e forma:SolidPeso molecolare:502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurezza:98.60%Colore e forma:Off-White To Pale-Yellow SolidPeso molecolare:479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurezza:98.27%Colore e forma:SoildPeso molecolare:657.7Ref: TM-T10398L
1mg201,00€5mg497,00€10mg701,00€25mg1.094,00€50mg1.508,00€100mg1.931,00€200mg2.637,00€Foralumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Purezza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidN-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formula:C25H28ClNOPurezza:99.15%Colore e forma:SolidPeso molecolare:393.95Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purezza:>95%Colore e forma:LiquidMeclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formula:C14H10Cl2NNaO2Purezza:98% - 98.96%Colore e forma:SolidPeso molecolare:318.14Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purezza:99.91%Colore e forma:SolidPeso molecolare:245.28Ref: TM-T12359
5mg48,00€10mg62,00€25mg97,00€50mg169,00€100mg250,00€200mg373,00€500mg612,00€1mL*10mM (DMSO)52,00€Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Purezza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Colore e forma:LiquidDarifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formula:C28H31BrN2O2Purezza:99.75% - >99.99%Colore e forma:SolidPeso molecolare:505.45CK-666
CAS:<p>CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.</p>Formula:C18H17FN2OPurezza:99.93%Colore e forma:SolidPeso molecolare:296.34NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purezza:99.84%Colore e forma:SolidPeso molecolare:676.73NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formula:C23H25ClF3N5OPurezza:99.35%Colore e forma:SolidPeso molecolare:479.93Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurezza:98.85% - 98.96%Colore e forma:SolidPeso molecolare:336.79Ref: TM-T13862
1mg46,00€2mg59,00€5mg87,00€10mg119,00€25mg187,00€50mg311,00€100mg502,00€200mg715,00€1mL*10mM (DMSO)105,00€Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Formula:C46H62N4O11Purezza:98.87% - 99.7%Colore e forma:Red-Violet Crystalline PowderPeso molecolare:847Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formula:C24H30F2O6Purezza:99.29% - 99.82%Colore e forma:Crystals From Acetone & Hexane SolidPeso molecolare:452.49Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purezza:97.05% - >99.99%Colore e forma:Blue-Black Solid From Water Ethanol SolidPeso molecolare:517.4Ethoxyquin
CAS:<p>Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.</p>Formula:C14H19NOPurezza:97.15% - 98.73%Colore e forma:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Peso molecolare:217.31BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formula:C24H30N8OPurezza:99.37%Colore e forma:SolidPeso molecolare:446.55AKE-72
CAS:<p>AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.</p>Formula:C30H29F3N6OPurezza:98.3%Colore e forma:SoildPeso molecolare:546.59Ref: TM-T80676
1mg94,00€2mg136,00€5mg224,00€10mg328,00€25mg505,00€50mg677,00€100mg929,00€200mg1.225,00€Akt3 degrader 1
CAS:Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Formula:C53H72N8O4Purezza:98.12% - 99.02%Colore e forma:SolidPeso molecolare:885.19Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purezza:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Colore e forma:LiquidMps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurezza:99.25%Colore e forma:SolidPeso molecolare:537.63Ref: TM-T16130
2mg37,00€5mg57,00€10mg92,00€25mg158,00€50mg269,00€100mg405,00€200mg568,00€1mL*10mM (DMSO)67,00€Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Purezza:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Colore e forma:LiquidBNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purezza:96.57%Colore e forma:SolidPeso molecolare:372.37Ref: TM-T14694
1mg84,00€5mg160,00€10mg226,00€25mg371,00€50mg520,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)170,00€TC113
TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.Formula:C37H50F2N12O13Colore e forma:SolidPeso molecolare:908.86Jatrophone
CAS:Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.Formula:C20H24O3Colore e forma:SolidPeso molecolare:312.4PROTAC BCR-ABL1 ligand 1
CAS:GMB-475 is a PROTAC ligand targeting BCR-ABL1 for degradation via E3 ligase recruitment.Formula:C17H12F3N3O2Colore e forma:SoildPeso molecolare:347.29Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Formula:C36H45ClN6O12Purezza:98%Colore e forma:SolidPeso molecolare:789.23MS170
CAS:MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.Formula:C45H56ClN9O7Colore e forma:SolidPeso molecolare:870.45DSPE-PEG5000-cRGD
DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.Colore e forma:Odour SolidSolidagonic acid
CAS:Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.Formula:C22H34O4Colore e forma:SolidPeso molecolare:362.5DSPE-PEG1000-iRGD
DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.Colore e forma:Odour SolidSQLE-IN-1
CAS:SQLE-IN-1 is a SQLE inhibitor with antitumor activity that inhibits the proliferation of Huh7 and the protein expression of PI3K and AKT.Formula:C24H21F2N5O2SPurezza:99.89%Colore e forma:SoildPeso molecolare:481.52Ref: TM-T83658
1mg92,00€5mg216,00€10mg354,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)47,00€MS21
CAS:MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.Formula:C58H79ClN12O6SColore e forma:SolidPeso molecolare:1107.86Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formula:C18H18Na4O12P2Colore e forma:SolidPeso molecolare:580.24PDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formula:C25H17N3O2SPurezza:99.93%Colore e forma:SoildPeso molecolare:423.4911H-Benzo[a]carbazole
CAS:11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.Formula:C16H11NPurezza:99.14%Colore e forma:SolidPeso molecolare:217.27MAL3-101
CAS:MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).Formula:C54H66N4O10Colore e forma:SolidPeso molecolare:931.12PM050489
CAS:PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Formula:C31H44ClN3O7Colore e forma:SolidPeso molecolare:606.15SNIPER(ABL)-058
CAS:SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL proteinFormula:C62H75N11O9SPurezza:98%Colore e forma:SolidPeso molecolare:1150.3920-O-Demethyl-AP3
CAS:<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Formula:C31H41ClN2O9Colore e forma:SolidPeso molecolare:621.12HSDVHK-NH2
CAS:Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.Formula:C30H48N12O9Purezza:98%Colore e forma:SolidPeso molecolare:720.78RA-PR058
RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.Formula:C11H15ClF3N3OColore e forma:SolidPeso molecolare:297.7Zolbetuximab MMAE
Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.Purezza:99.19% (SEC-HPLC) - 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:150 kDa4,4'-Di-O-methylellagic acid
CAS:4,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences. The catalog number is T125016 and the CAS number is 3374-77-4.Formula:C16H10O8Colore e forma:SolidPeso molecolare:330.248ML 2-23
ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].Formula:C47H53BrCl2N10O7SPurezza:98%Colore e forma:SolidPeso molecolare:1052.86Eudebeiolide B
CAS:Eudebeiolide B, isolated from Salvia plebeia R.Formula:C15H18O4Purezza:98%Colore e forma:SolidPeso molecolare:262.3Protein Kinase C (19-36)
CAS:Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.Formula:C93H159N35O24Purezza:98%Colore e forma:SolidPeso molecolare:2151.48Gamitrinib TPP
CAS:Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formula:C52H65N3O8PPurezza:98%Colore e forma:SolidPeso molecolare:891.078HA15-Biotin
CAS:HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.Formula:C37H45N7O5S3Colore e forma:SolidPeso molecolare:763.99Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS:Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.Formula:C56H110N22O14Purezza:98%Colore e forma:SolidPeso molecolare:1315.61ML-B01
<p>ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.</p>Formula:C24H31Cl2N5OColore e forma:SolidPeso molecolare:476.44Sangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Formula:C12H15N5O5Purezza:99.85%Colore e forma:SolidPeso molecolare:309.28Abl Cytosolic Substrate
CAS:Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).Formula:C64H101N15O16Purezza:98%Colore e forma:SolidPeso molecolare:1336.58Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purezza:99.57%Colore e forma:SolidPeso molecolare:447.48Chaetominine
CAS:Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.Formula:C22H18N4O4Colore e forma:SolidPeso molecolare:402.40Myosin V-IN-1
CAS:<p>Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.</p>Formula:C29H26N6O3SPurezza:98.64% - 98.64%Colore e forma:SolidPeso molecolare:538.62GRGDSP
CAS:Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.Formula:C22H37N9O10Purezza:98%Colore e forma:SolidPeso molecolare:587.58Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Formula:C46H54O16Purezza:98%Colore e forma:SolidPeso molecolare:862.91MS98
CAS:<p>MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.</p>Formula:C58H81ClN10O7SColore e forma:SolidPeso molecolare:1097.86Tubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Formula:C28H25N3O4SColore e forma:SolidPeso molecolare:499.58PKCiota-IN-2
CAS:PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Formula:C24H21N5OPurezza:98.86%Colore e forma:SolidPeso molecolare:395.46Ref: TM-T9863
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€1mL*10mM (DMSO)279,00€DSPE-PEG1000-cRGD
DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.Colore e forma:Odour SolidCatumaxomab
CAS:Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Purezza:95%Colore e forma:LiquidPeso molecolare:146.73 kDaβ-catenin-IN-37
CAS:β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.Formula:C13H9N9OColore e forma:SolidPeso molecolare:307.277Gly-Arg-Gly-Asp-Ser
CAS:Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.Formula:C17H30N8O9Purezza:98%Colore e forma:SolidPeso molecolare:490.47LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurezza:98%Colore e forma:SolidPeso molecolare:1368.53Fibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Formula:C38H64N8O15Purezza:98%Colore e forma:SolidPeso molecolare:872.96Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formula:C83H127N25O34SPurezza:98%Colore e forma:SolidPeso molecolare:2051.11187-1, N-WASP inhibitor
CAS:<p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>Formula:C96H122N18O16Purezza:98%Colore e forma:SolidPeso molecolare:1784.13PKC β pseudosubstrate
CAS:Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).Formula:C177H294N62O38S3Purezza:98%Colore e forma:SolidPeso molecolare:3994.84β-catenin-IN-7
β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, andFormula:C17H13BrN2O2SColore e forma:SolidPeso molecolare:389.27Ac-MRGDH-NH2
Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.Formula:C25H41N11O8SColore e forma:SolidPeso molecolare:655.727Pep2m, myristoylated
CAS:Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.Formula:C63H118N18O14SPurezza:98%Colore e forma:SolidPeso molecolare:1383.8DSPE-PEG2000-iRGD
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.Colore e forma:Odour SolidAB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formula:C137H215IN30O45SColore e forma:SolidPeso molecolare:3161.32AS-605240 potassium
AS-605240 (potassium) is an orally active PI3Kγ inhibitor with an IC50 of 8 nM and a Ki of 7.8 nM. It inhibits MCP-1 and CSF1-induced PKB phosphorylation with IC50 values of 0.181 µM and 0.550 µM, respectively. In mouse models of peritonitis induced by RANTES (CCL5) and thioglycolate, AS-605240 (potassium) reduces neutrophil recruitment, showing EC50 values of 9.1 mg/kg and 10 mg/kg. Additionally, AS-605240 (potassium) ameliorates arthritis induced by αCII-IA in mice.Formula:C12H6KN3O2SColore e forma:SolidPeso molecolare:294.98178Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormula:C17H13ClN6OSColore e forma:SolidPeso molecolare:384.84Akt/SKG Substrate Peptide
CAS:substrate for Akt/PKBFormula:C36H59N13O9Purezza:98%Colore e forma:SolidPeso molecolare:817.94Wortmannin-Rapamycin Conjugate
CAS:Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer.Formula:C88H131N3O23Colore e forma:SolidPeso molecolare:1599.014K34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formula:C26H30ClN3O4Purezza:99.76% - 99.89%Colore e forma:SoildPeso molecolare:483.99Ref: TM-T41151L
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€Chemerin-9 (149-157)
CAS:Chemerin-9, a nonapeptide C-terminal fragment of chemerin, retains full protein's activity as a ChemR23 agonist.Formula:C54H66N10O13Purezza:98%Colore e forma:SolidPeso molecolare:1063.16trans-Dehydrocurvularin
CAS:trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.Formula:C16H18O5Colore e forma:SolidPeso molecolare:290.315PROTAC BCR-ABL Degrader-1
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway andFormula:C43H40N10O6Purezza:98%Colore e forma:SolidPeso molecolare:792.84Ceratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Formula:C17H16Br2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:468.14Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Colore e forma:Odour LiquidVinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formula:C45H54F2N4O8·xC4H6O6Purezza:98%Colore e forma:SolidPeso molecolare:967.02Ref: TM-T6722
2mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)Prezzo su richiestaALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Formula:C47H62Cl2N4O9SPurezza:98%Colore e forma:SolidPeso molecolare:929.99Crosstide
CAS:Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.Formula:C48H77N17O17Purezza:98%Colore e forma:SolidPeso molecolare:1164.23PDI-IN-4
PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.Formula:C17H12F3NO2Colore e forma:SolidPeso molecolare:319.278Hypoglycemic agent 3
Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.Formula:C32H51NO5Colore e forma:SolidPeso molecolare:529.751KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFormula:C24H21NO5Colore e forma:SolidPeso molecolare:403.43Box5 TFA
Box5 TFA, a potent Wnt5a antagonist, impedes Wnt5a signaling, restricts Wnt5a-initiated Ca2+ release, and hampers cell migration, showing promise for melanomaFormula:C32H51F3N6O15S2Colore e forma:SolidPeso molecolare:880.96BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Formula:C45H47Br2N2O3PColore e forma:SolidPeso molecolare:854.65para-amino-Blebbistatin
CAS:<p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>Formula:C18H17N3O2Colore e forma:SolidPeso molecolare:307.353SNIPER(ABL)-047
SNIPER(ABL)-047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels,Formula:C67H82F3N11O9SPurezza:98%Colore e forma:SolidPeso molecolare:1274.5Fuzapladib
CAS:<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formula:C15H20F3N3O3SPurezza:99.87%Colore e forma:SoildPeso molecolare:379.4Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColore e forma:SolidPeso molecolare:356.83MK2-IN-5
CAS:MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway andFormula:C61H113N21O16Purezza:98%Colore e forma:SolidPeso molecolare:1396.68Myelin Basic Protein
CAS:Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.Formula:C60H103N21O17Purezza:98%Colore e forma:SolidPeso molecolare:1390.59Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFormula:C22H25NO6Colore e forma:SolidPeso molecolare:399.447-Epi-10-oxo-docetaxel
CAS:7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Formula:C43H51NO14Purezza:98%Colore e forma:SolidPeso molecolare:805.86Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Purezza:98%Colore e forma:Odour SolidAlvespimycin TFA
Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.Formula:C34H49F3N4O10Colore e forma:SolidPeso molecolare:730.34008Rotigaptide
CAS:Rotigaptide, modulates Cx43 for gap junctions, counteracts uncoupling, and maintains communication under stress.Formula:C28H39N7O9Purezza:98%Colore e forma:SolidPeso molecolare:617.65DynaMin inhibitory peptide, myristoylated
CAS:Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.Formula:C61H107N19O14Purezza:98%Colore e forma:SolidPeso molecolare:1330.64AD57
CAS:<p>AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.</p>Formula:C22H20F3N7OPurezza:99.05%Colore e forma:SoildPeso molecolare:455.44Coronaridine
CAS:<p>Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.</p>Formula:C21H26N2O2Colore e forma:SolidPeso molecolare:338.451NMS-E973
CAS:NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.Formula:C22H22N4O7Purezza:99.84%Colore e forma:SolidPeso molecolare:454.43Ref: TM-T6609
2mg42,00€5mg64,00€10mg97,00€25mg197,00€50mg310,00€100mg442,00€200mg622,00€1mL*10mM (DMSO)70,00€JG-258
CAS:JG-258 is an inactive negative control for Hsp70 inhibitors [1] .Formula:C20H22ClN3OS3Colore e forma:SolidPeso molecolare:452.06α2β1 Integrin Ligand Peptide
CAS:The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellularFormula:C14H22N4O9Purezza:98%Colore e forma:SolidPeso molecolare:390.35AKTide-2T
CAS:Peptide substrate for Akt/PKBFormula:C74H114N28O20Purezza:98%Colore e forma:SolidPeso molecolare:1715.87Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].Formula:C35H39N9O3Colore e forma:SolidPeso molecolare:633.74MS15 TFA
MS15 TFA is a potent, selective AKT PROTAC degrader, effectively inhibiting AKT1, AKT2, and AKT3 with IC50 values of 798 nM, 90 nM, and 544 nM, respectively [1Formula:C66H80F3N11O7SPurezza:98%Colore e forma:SolidPeso molecolare:1228.47TAT-Gap19
CAS:Cx43 blocker, IC50 ~7μM; doesn't affect gap junctions/Panx1. TAT motif enhances effect; works in vivo, brain-penetrant.Formula:C119H212N46O26Purezza:98%Colore e forma:SolidPeso molecolare:2703.28T-808
CAS:T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Formula:C17H19FN4Colore e forma:SolidPeso molecolare:298.36SNIPER(ABL)-050
SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.Formula:C68H84N12O9Purezza:98%Colore e forma:SolidPeso molecolare:1213.47PROTAC HSP90 degrader BP3
CAS:PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.Formula:C32H29ClN8O5Colore e forma:SolidPeso molecolare:641.08Kanosamine hydrochloride
CAS:Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species.Formula:C6H14ClNO5Purezza:98%Colore e forma:SolidPeso molecolare:215.63Ref: TM-T11743
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiestaFoxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purezza:98%Colore e forma:SolidPeso molecolare:694.77SIAIS178
CAS:SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).Formula:C50H62ClN11O6S2Purezza:98.07%Colore e forma:SolidPeso molecolare:1012.68Ref: TM-T12907
1mg160,00€5mg376,00€10mg512,00€25mg938,00€50mg1.510,00€100mg2.167,00€200mg2.822,00€1mL*10mM (DMSO)414,00€SNIPER(ABL)-020
SNIPER(ABL)-020, a Dasatinib-Bestatin conjugate via linker, inhibits ABL and targets IAP, reducing BCR-ABL protein.Formula:C44H59ClN10O8SPurezza:98%Colore e forma:SolidPeso molecolare:923.52Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formula:C12H12O9Colore e forma:SolidPeso molecolare:300.2210-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formula:C43H51NO14Purezza:98%Colore e forma:SolidPeso molecolare:805.874SNIPER(ABL)-019
SNIPER(ABL)-019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting aFormula:C60H77ClN12O9SPurezza:98%Colore e forma:SolidPeso molecolare:1177.852-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.Formula:C12H24ClNO4Colore e forma:SolidPeso molecolare:281.78Epothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formula:C27H41NO7SColore e forma:SolidPeso molecolare:523.68Aberrant tau degrader 2
CAS:Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.Formula:C19H27N7O3SColore e forma:SolidPeso molecolare:433.528KT D606
CAS:<p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>Formula:C59H50N6O10Colore e forma:SolidPeso molecolare:1003.06Pironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purezza:98%Colore e forma:SolidPeso molecolare:324.45hAChE-IN-1
hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.Formula:C22H24N4OColore e forma:SolidPeso molecolare:360.45Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFormula:C24H20FN3O3Colore e forma:SolidPeso molecolare:417.43αVβ8-IN-1
CAS:<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formula:C25H32ClN5O4Colore e forma:SolidPeso molecolare:502.01α-Linolenic Acid (sodium salt)
CAS:<p>α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.</p>Formula:C18H29NaO2Colore e forma:SolidPeso molecolare:300.41Chromeceptin
CAS:Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.Formula:C19H16F3N3OPurezza:99.85%Colore e forma:SoildPeso molecolare:359.35LY 379196
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.Formula:C30H34N4O5SColore e forma:SolidPeso molecolare:562.68st-Ht31
CAS:Ht-31 stearate: Blocks RII subunits of PKA & AKAP interaction in cells; cell-permeable.Formula:C129H217N29O39Purezza:98%Colore e forma:SolidPeso molecolare:2798.27gp96-II
<p>Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.</p>Formula:C200H353N59O53SColore e forma:SolidPeso molecolare:4464.37DSPE-PEG2000-cRGD
DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.Colore e forma:Odour SolidTNIK-IN-7
CAS:TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cellsFormula:C23H22N4O2Purezza:99.87%Colore e forma:SoildPeso molecolare:386.45
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