Composti deuterati

Applications Labelled Diflufenican (D445640). (Pre and post emergence foliar absorbed herbicide for winter weed control in cereal crops; carotenoid biosynthesis inhibitor.
References Conte, E., et al.: J. Agric. Food Chem., 46, 4766 (1998),

Applications Diphenyl-2,2',4,4',6,6'-d6-amine (CAS# 99234-91-0) is a useful isotopically labeled research compound.

Applications Cefepime-D8 sulfate is a labelled analogue of Cefepine sulfate, a cephalosporin that has antibacterial effects against Gram-positive and Gram-negative bacteria. Cefepime sulfate is used to treat mild to severe bacterial infections.
References Neu, H.: Am. J. Med., 100, 68S (1996); Sanders, C.: Clin. Infect. Dis., 17, 369 (1993); Sanders, W., et al.: Clin. Infect. Dis., 23, 454 (1996); Yahav, D., et al.: Lancet Infect. Dis., 7, 338 (2007)

Applications tert-Butyl-d9 4-Nitrophenyl Carbonate (cas# 1190006-35-9) is a compound useful in organic synthesis.

Applications 4-Nitroaniline-2,3,5,6-D4 is a labelled analogue of 4-Nitroaniline (N490770). 4-Nitroaniline is used in the synthesis of photorefractive polymers, as novel chromophores in analytical study. As well, due to the absorption spectrum associated with 4-Nitroaniline, it is used to determine catechol derivatives in syntheses.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nagaraja, P. et al.: J. Pharm. Biomed. Anal., 25, 417 (2001)

Applications Isotope labelled analog of α-D-Galactose 1-Phosphate, the phosphate conjugate of α-D-Galactose (G155260), a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains.
References Sang, J.L., et al.: J. Bacteriol., 190, 7932 (2008);

Applications Emamectin-d3 is deuterium labeled emamectin, a soluble derivative of avermectin and used as parasiticide and insecticide. Emamectin activates glutamate-gated chloride channels.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xu X., et al.: Biochem Biophys Res Commun 473, 795 (2016); Lumaret, J. P., et al.: Curr Pharm Biotechnol. 13, 1004 (2012)

Applications Bisphenol AF-d4 is the isotope labelled analog of Bisphenol AF (2,2-Bis-(4-hydroxyphenyl)hexafluoropropane). 2,2-Bis-(4-hydroxyphenyl)hexafluoropropane (B447290) acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor ERα. It is a full agonist for the estrogen receptor.
References Matsushima, A. et al.: Environ. Health, Perspect. 118, 1267 (2010)

Applications 16alpha-Hydroxy-17beta-estradiol-2,4-d2 (CAS# 53866-32-3) is a useful isotopically labeled research compound.

Applications L-Methionine Sulfoxide 13C1 is a labelled analogue of L-Methionine Sulfoxide ( M260450). L-Methionine Sulfoxide ( M260450) an intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.
References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008);Balog, E., et al.: Biochem., 48, 3005 (2009);

Applications 4-Ethylphenyl-d4 Sulfate Potassium Salt is the isotope labelled analog of 4-Ethylphenyl Sulfate Potassium Salt (E925865); a newly identified uremic substance.
References Kaori, K., et al.: J. Chromatogr. B, 878, 2997 (2010)

Applications 4-(2-(4-Chlorobenz-d4-amido)ethyl)phenyl 4-Chlorobenz-d4-oate is an intermediate in the synthesis of Bezafibrate-d4 (B341002), a labeled antilipemic agent.
References Zimmerman, R., et al.: Atherosclerosis 29, 477 (1978), Monk, J.P., et al.: Drugs, 33, 539 (1987)

Stability Light and temperature Sensitive
Applications 2,2-Dichloroacetic Acid-1-13C is derived from Barium Carbonate-13C (B118672), which is a stable Barium Carbonate isotope used for studies on drug metabolism.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Horie, M. et al.: Yakug. Zas., 97, 805 (1977);

Stability Hygroscopic
Applications Guaiacol-beta-D-glucopyranoside-d3, is a labeled analogue of Guaiacol-beta-D-glucopyranoside (G245565), a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications Medetomidine-d5 (d5-Major) is an intermediate in the synthesis of Dexmedetomidine-d4 L-Tartrate (d4-Major) (D299006). Dexmedetomidine-d4 L-Tartrate is the labeled salt analogue of Dexmedetomidine (D299000), an α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.
References Rajala, R., et al.: Eur. J. Pharm. Sci., 1, 219 (1994); Jalonen, J., et al.: Anesthesiology, 86, 331 (1997); Talke, P., et al.: Anesth. Analg., 85, 1136 (1997); Bhana, N., et al.: Drugs, 59, 263 (2000)

Applications Hexanoic-d11 Acid acts as a reagent in the synthesis of per-deuterated alkyl amines for preparation of deuterated organic pyromellitamide gelators.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yepuri, N. R.; Tetrahedron Lett., 54, 2538 (2013)

Applications Propoxyphenyl-​thiohydroxyhomosilde​nafil-d4 is labelled Propoxyphenyl-thiohydroxyhomosildenafil (P831630), an analogue of Hydroxythiohomo Sildenafil (H963150).
References Balayssac, S., et. al.: J. Pharmaceut. Biomed., 63, 135 (2012)

Applications Glutaric Acid-1,5-13C2 (cas# 1185108-16-0) is a compound useful in organic synthesis.

Stability Light Sensitive
Applications A labelled derivatized of 3-amino-2-oxazolidone (AOZ, A618570), a metabolite of Furazolidone and Nitrofuran.Environmental contaminants; Food contaminants; Heat processing contaminants
References Vroomen, L., et al.: Drug Metab. Rev., 22, 663 (1990), Hoogenboom, L., et al.: Food Chem. Toxicol., 29, 185 (1991), McCracken, R., et al.: Food Addit. Contam., 17, 75 (2000),

Applications Adamantane-d16 is used in the fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. Unlabeled adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, C. et al.: Inorg. Chem. 45, 4769 (2012); Thomas. A. et al.: J. Neurosci., 25, 3312 (2005); Deyde, V. et al.: Exp. Rev. Mol. Diag., 9, 493 (2009);